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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes
منشور في 2021"…</p><h3>Conclusions</h3><p dir="ltr">Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Mutation of the two residues in NLuc revealed a decreased but stable activity of the R162A, but not Q32A, mutant NLuc in live cell and in vitro assays performed using lysates prepared from cells expressing the proteins and with the furimazine substrate. …"
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
منشور في 2021"…This study aims to investigate the inhibitory effect of metformin on VISTA via AHR in melanoma cells (CHL-1, B16) and animal models. VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. …"
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Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis
منشور في 2019"…<h3>Background</h3><p dir="ltr">Brief intervention is a critical method for identifying patients with problematic substance use in primary care settings and for motivating them to consider treatment options. …"
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The Pros and Cons of Use of Handheld Electronic Devices During Ward Rounds and the Impact of the COVID-19 Pandemic
منشور في 2023"…The COVID-19 pandemic led to a decrease in the use of HEDs by both faculty [38(64%)] and PGTs [42(60%)].…"
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The impact of COVID‐19 pandemic lockdown on smoking habits and lifestyle: A cross‐sectional study
منشور في 2023"…</p><h3>Methods</h3><p dir="ltr">A cross‐sectional online survey was designed using the Google Forms service and distributed by social media platforms. …"
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Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar
منشور في 2024"…This study investigates the impact of land use and land cover changes on summer and winter LSTs in Doha and Al Dayeen municipalities of Qatar, spanning from the years 2000 to 2023, using remote sensing techniques and Geographic Information Systems (GIS). …"
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Evidence-based safety education and training for traffic injury prevention
منشور في 2015"…Bicycle skill training for children and youth may increase their safety knowledge, but not necessarily improve their behavior or decrease their injury rates. Non-legislative interventions were found effective for increasing observed helmet use among bicyclists. …"
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An Experimental Investigation of the Effects of Dressing and Grinding Parameters on Sustainable Grinding of Inconel 738 Used for Automated Manufacturing
منشور في 2023"…In other words, increasing the dressing feed rate during dressing of the grinding wheel using a multipoint dresser makes a finer wheel surface topography and as a result decreases the surface roughness of the ground workpiece compared to a single-edge dresser. …"
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The Triple “S” Impact of COVID-19: Nationwide Evidence of the Impact of the Stress Associated With Restrictive Measures on Substance Use, Sleep, and Social Connectedness in Qatar...
منشور في 2023"…Of tobacco users in our sample, 36% reported increased tobacco use since the start of home confinement, while 41.6% of alcohol users reported decreased alcohol use. …"
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Use of Carbide Derived Carbon in Water Treatment and Thermal Fluids Applications
منشور في 2021"…More than 26% enhancement in thermal conductivity of thermal fluids was obtained by using 0.3 wt% CDC. These findings indicate a promising potential of using CDC for heat transfer applications such as heat exchangers and district cooling units.…"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …"
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Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar
منشور في 2024"…This study investigates the impact of land use and land cover changes on summer and winter LSTs in Doha and Al Dayeen municipalities of Qatar, spanning from the years 2000 to 2023, using remote sensing techniques and Geographic Information Systems (GIS). …"
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Psychological inoculation against problematic social media use among adolescents: An experimental study
منشور في 2025"…A mixed ANCOVA was employed to test the intervention's impact on PSMU, post‐intervention attitude changes, and post‐inoculation talk (PIT) about excessive technology use. Results indicated a significant decrease in PSMU levels following active inoculation, particularly in withdrawal, persistence, displacement, and deception symptoms. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Here, we dissect the mechanism underlying the increased binding affinity of the N501Y mutant for ACE2 using molecular dynamics (MD) simulations of the available ACE2-S1-RBD complex structure (6M0J) and show a prolonged and stable interfacial interaction of the N501Y mutant S1-RBD with ACE2 compared to the wild type S1-RBD. …"
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Intracellular Ionic Strength Sensing Using NanoLuc
منشور في 2021"…Biochemical experiments using a recombinantly purified protein showed that NanoLuc bioluminescence is dependent on the ionic strength of the reaction buffer for a wide range of ionic strength conditions. …"
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Efficacy and safety of using Etelcalcetide for controlling secondary hyperparathyroidism
منشور في 2024"…</p><h3>Results</h3><p dir="ltr">Patients within the PTH target range of 150 to 500pg/ml improved from 8% in June 2021 (on Cinacalcet) to 54% in June 2023 (on Etelcalcetide) (p=0 .0032) while patients with PTH above 1,000pg/ml decreased from 50% to 4% during the same period (p=0.00001) (Figure 2). …"
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Luspatercept's use in a patient with transfusion‐dependent beta‐thalassemia and intrathoracic extramedullary hematopoiesis (EMH)
منشور في 2024"…While also highlighting the benefits of using luspatercept regarding decreasing the iron overload and improving hemoglobin levels and examining how it was used safely to manage a transfusion‐dependent thalassemia patient with an extramedullary hematopoiesis mass with no adverse events of note.…"