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    The effects of oxygen concentration on in vitro output of prostaglandin E2 and interleukin-6 from human fetal membranes. حسب Al-Asmakh, Maha

    منشور في 2007
    "…In this study, we have investigated the effect of oxygen tension on fetal membrane biology, as a reconsideration of the literature suggests that fetal membranes are normally exposed to approximately 3% O(2) (approximately 20 mmHg) in vivo, rather than the 20% O(2) (150 mmHg) used for in vitro culture. The output of prostaglandin E(2) from non-activated fetal membranes in response to IL-1beta was decreased by approximately 80% at 16 and 24 h of culture, whereas the inhibition of IL-6 production was time-dependent, reaching 90% after 16 h and 50% after 24 h. …"
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