Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies حسب Fawaz E., Alanazi

"…This study aims to investigate the inhibitory effect of metformin on VISTA via AHR in melanoma cells (CHL-1, B16) and animal models. VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"

Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis حسب George Nitzburg (18614989)

Drying Studies of Purple Non-Sulphur Bacterial Biomass and Application as a Single-Cell Protein Feed for <i>Litopenaeus vannamei</i> حسب Asifa Anwar (20884229)

"…The Ameri model fitted the best in cases of 60℃ and 80℃ in all of the considered thickness of biomass, while the Midilli-Kucuk model performed better at 100℃ and 120℃ for the majority of the thicknesses (with the exception of Page model in case of 2 mm at 100℃ and 4 mm at 120℃) where temperature gradients across the biomass become more pronounced. …"

Anabolic steroids-induced delirium حسب Mohamed Adil Shah Khoodoruth (14589828)

"…Psychiatric aspects are of particular importance and include psychosis, delirium, mania, depression, and aggression. We describe the case of a young gentleman who was managed as a case of androgenic steroid induced delirium.…"

Old subjects with sepsis in the emergency department: trend analysis of case fatality rate حسب Andrea Fabbri (356760)

"…We aimed to assess the case fatality rate (CFR) and its predictors in subjects with sepsis admitted to a general Italian hospital from 2009 to 2016, stratified by risk score.…"

Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes حسب Maryam Aghadi (17128819)

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 حسب Olfa Khalifa (10914452)

"…Furthermore, confocal microscopy analysis of BODIPY-stained untreated, steatotic, and Ex-4-treated steatotic cells showed that Ex-4 significantly decreases the number of lipid droplets. Fatty acid uptake and transport genes were also affected by MALAT1 knockdown. …"

A dramatized method for teaching undergraduate students responsible research conduct حسب Kuei-Chiu Chen (14108854)

The Pros and Cons of Use of Handheld Electronic Devices During Ward Rounds and the Impact of the COVID-19 Pandemic حسب Shireen Suliman (13554986)

Non-diabetic ketoacidosis secondary to primary hyperthyroidism حسب Abdulrahman F. Al-Mashdali (17148316)

"…To the best of our knowledge, our case is the third report of NDKA related to thyrotoxicosis.…"

Light chain amyloidosis presenting with autoimmune hepatitis-primary sclerosing cholangitis overlap syndrome حسب Hammad Shabir Chaudhry (20376378)

"…Primary biliary cirrhosis or primary sclerosing cholangitis (PSC) with autoimmune hepatitis (AIH) overlap syndrome is a very unusual presentation of systemic amyloidosis and to the best of our knowledge, not reported before. We present a rare case of a 46-years-old female with systemic amyloidosis secondary to AL amyloidosis manifesting primarily as nephrotic syndrome and AIH-PSC overlap syndrome.…"

Predictors of mortality and morbidity in critically ill COVID‐19 patients: An experience from a low mortality country حسب Mohamad Y. Khatib (11659459)

"…Factors independently associated with mortality included older age ([OR]; 2.3 [95% CI; 1.92–2.75] for each 10-year increase in age, <i>p</i> < 0.001), chronic kidney disease (OR; 1.9 [95% CI; 1.02–3.54], <i>p</i> = 0.04), active malignancy (OR; 6.15 [95% CI; 1.79–21.12], <i>p</i> = 0.004), lower platelet count at ICU admission (OR; 1.41 [95% CI; 1.13–1.75] for each 100 × 103/µl decrease, <i>p</i> = 0.002), higher neutrophil-to-lymphocyte ratio at admission (OR; 1.01 [95% CI; 1–1.02] for each 1- point increase, <i>p</i> = 0.016), higher serum ferritin level at admission (OR; 1.05 [(95% CI; 1.02–1.08] for each 500 µg/L increase, <i>p</i> = 0.002), and higher serum bilirubin level at admission (OR; 1.19 [95% CI; 1.04–1.36] for each 10 μmol/L increase, <i>p</i> = 0.01). …"

Providing Health Care in Armed Conflict Countries: The Case of Yemen حسب Esraa Ali Sayed Ali (20741327)

Hypertension as an Unusual Cause of Proliferative Retinopathy: Case Report and Literature Review حسب Rami Hasan Saleem Abu Sbeit (16444658)

"…<p>Malignant hypertensive retinopathy is associated with characteristic fundus findings that typically do not include proliferative retinal vascular changes. We present the case of a 34-year-old patient who had bilateral decreased vision and was found to have malignant hypertension with hypertensive retinopathy changes along with unforeseen bilateral neovascularization and vitreous hemorrhage. …"

Influence of temperature on tire-pavement noise in hot climates: Qatar case حسب Okan, Sirin

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Influence of temperature on tire-pavement noise in hot climates: Qatar case حسب Okan Sirin (14603304)

"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"

Acute spasticity in malignant MCA stroke: a case report and review of literature حسب Muhammad Faizan (12710607)

"…However, an acute onset of spasticity at presentation is extremely rare. We report a case of a 40-year-old male patient who presented with spasticity accompanied by aphasia and decreased consciousness. …"

A Case Study to Identify the Hindrances to Widespread Adoption of Electric Vehicles in Qatar حسب Amith Khandakar (14151981)

A Severe Case of Overlap of Morphea and Eosinophilic Fasciitis after Burn Injuries حسب Hania Sami (21436013)

"…The coexistence of the two is extremely rare and has a poorer prognosis. Our case report is one of the first to report burn injuries as a trigger factor for EF and generalized morphea overlap. …"