Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

“…This study aims to investigate the inhibitory effect of metformin on VISTA via AHR in melanoma cells (CHL-1, B16) and animal models. VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. …”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

“…This study aims to investigate the inhibitory effect of metformin on VISTA via AHR in melanoma cells (CHL-1, B16) and animal models. VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. …”
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Oral PTCTS (Particulated Transialidase) Removes Serum Microparticles and Decreases Inflammation in Atherosclerotic Plaques of Rabbits by Garavelo, Sherrira M.

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Thiostrepton inhibits growth and induces apoptosis by targeting FoxM1/SKP2/MTH1 axis in B-precursor acute lymphoblastic leukemia cells by Kuttikrishnan, Shilpa

“…In the current study, we showed that the downregulation of FoxM1 by its inhibitor thiostrepton inhibited cell viability and induced caspase-dependent apoptosis in a panel of B-pre-ALL cell lines. Thiostrepton led downregulation of FoxM1 accompanied by decreased expression of Aurora kinase A, B, matrix metalloproteinases, and oncogene SKP2 as well as MTH1. …”
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Opportunities, challenges and trade-offs with decreasing avoidable food waste in the UK by Patel, Shivalee

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Decreased soil moisture due to warming drives phylogenetic diversity and community transitions in the tundra by Scharn, Ruud

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Hyperhydration-induced decrease in urinary luteinizing hormone concentrations of Male athletes in doping control analysis by Athanasiadou, Ioanna

“…A comparison of the measured LH values for both hyperhydration phases (Phase A: 4.24 � 5.60 IU/L and Phase B: 4.74 � 4.72 IU/L) with the baseline (''normal'') values showed significant differences (Phase A: p < .001 and Phase B: p < .001), suggesting the clear effect of urine dilution due to hyperhydration. …”
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Decreased weight gain and enhanced serum biochemical parameters in rats after vitamin D and Ca supplementation by Subih H.

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Evidence of two mechanisms involved in Bacillus thuringiensis israelensis decreased toxicity against mosquito larvae: Genome dynamic and toxins stability by Elleuch, Jihen

“…The obtained results describe two main reasons of the decrease of B. thuringiensis israelensis insecticidal activity. …”
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Decreasing the use of edible oils in China using WeChat and theories of behavior change: study protocol for a randomized controlled trial. by Zhu, Rui

“…A total of 200 participants will be selected and randomly assigned to two equal-sized groups: group A (the intervention group) and group B (the control group). Group A will receive health education regarding edible oils for four consecutive weeks, whereas group B will be treated as the blank control. …”
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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes. by Ramanjaneya, Manjunath

“…Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …”
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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Improvement in properties of Ni-B coatings by the addition of mixed oxide nanoparticles by Bahgat Radwan, A.

“…Similarly, corrosion inhibition efficiency of binary Ni-B coatings is considerably improved which can be presumably regarded as the effect of formation of dense structure and decrease in active area of Ni-B matrix due to incorporation of mixed inactive nanoparticles. …”
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Profiling of intestinal microbiota in patients infected with respiratory influenza a and b viruses by Al Khatib, Hebah A.

“…Overall, infected patients experienced an increased abundance of Bacteroidetes and a corresponding decrease in Firmicutes. Differential abundance testing illustrated that differences in gut microbiota composition were influenza type-dependent, identifying ten differentially abun-dant operational taxonomic units (OTUs) between influenza A-and influenza B-infected patients. …”
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Using B4C nanoparticles to enhance thermal and mechanical response of aluminum by Ubaid, Fareeha

“…It was observed that the density decreased and porosity increased with an increase in B4C content in aluminum matrix. …”
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Aluminum nitride (AlN) reinforced electrodeposited Ni-B nanocomposite coatings by Radwan, A. Bahgat

“…The incorporation of AlN nanospecies into the Ni–B matrix coating decreased the porosity of the cauliflower-like structure and improved the mechanical properties including hardness and wear. …”
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Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes), Supplementation Alters Gut Microbiome and Corrects Dyslipidemia in Rats. by Anwar, Haseeb

“…Wistar rats were offered a chow maintenance diet (CMD; CON group) or the same CMD ration with cholesterol (1.5% w/w) and cholic acid (0.5% w/w) added to induce hypercholesterolemia (day 1 to day 24). …”
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Magneto-Mechanical and Thermal Properties of Nd-Fe-B-Epoxy-Bonded Composite Materials by Grujić, Aleksandar

“…The results show that impact toughness decreases, while magnetic properties increase, along with increasing content of Nd-Fe-B. …”
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Anticancer activity of Neosetophomone B, A Fungal Secondary Metabolite, against Hematological Malignancies by Kuttikrishnan, Shilpa

“…We tested a panel of leukemic cell lines with different doses of NSP-B. Cell viability decreased in a concentration-dependent manner in K562 and U937 cell lines. …”
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Heme Oxygenase Isoform 1 Regresses Cardiomyocyte Hypertrophy Through Regressing Sodium Proton Exchanger Isoform 1 Activity by Sobh, Ahmed

“…Results: Our results showed a significant decrease in HO-1 mRNA expression in cardiomyocytes expressing active NHE1 (74.84 ± 9.19 % vs. 100 % normal NHE1 expression, p<0.05). …”
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