Search alternatives:
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), awd decreased (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
16 mean » 16 men (Expand Search), 19 means (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), awd decreased (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
16 mean » 16 men (Expand Search), 19 means (Expand Search)
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GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age.
Published 2021“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver.
Published 2021“…(A-B) GCase levels as assessed by the CBE/4-MU method are significantly decreased in the het <i>GBA1</i> D409V KI mice at 5 months of age in both brain (A) and liver (B). …”
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FTY720 treatment decreased tumor growth in a xenograft model of hepatoblastoma.
Published 2019“…<p>(A) HuH6 cells (2.5 x 10<sup>6</sup> cells in 25% Matrigel) were injected subcutaneously into the right flank of 6-week-old female athymic nude mice. …”
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Decreased activity of FASII favors the cold growth of the <i>ΔcshA</i> strain.
Published 2020“…<i>fapR</i> mRNA levels were quantified by RT-qPCR using 16S rRNA as reference gene on total RNAs extracted from <i>wt</i> strain (PR01), <i>ΔcshA</i> strain (PR01-ΔcshA), and suppressor strains <i>ΔcshA/accC</i><sup><i>M385V</i></sup> (C51), <i>ΔcshA/accC</i><sup><i>T183I</i></sup> (sup30), <i>ΔcshA/accD</i><sup><i>F253V</i></sup> (sup17), <i>ΔcshA/accD</i><sup><i>A164V</i></sup> (sup16), <i>ΔcshA/birA</i><sup><i>D320F-FsX28</i></sup> (C58), <i>ΔcshA/birA</i><sup><i>R280stop</i></sup> (sup1) and <i>ΔcshA/bioY</i><sup><i>P123R-FsX1</i></sup> (C66), all at exponential growth phase in MH medium at 25°C. n = 5 for <i>ΔcshA</i>, <i>4 for wt</i> and 3 for all others. …”
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