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point decrease » point increase (Expand Search)
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72041
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72043
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72044
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72045
<em>C. elegans</em> VANG-1 Modulates Life Span via Insulin/IGF-1-Like Signaling
Published 2012“…We show that two alleles of <em>vang-1</em> and depletion of the protein by RNAi cause an increase of mean life span up to 40%. …”
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72046
Effects of common genetic variants of human uridine diphosphate glucuronosyltransferase subfamilies on irinotecan glucuronidation
Published 2022“…Furthermore, the variants of these isoforms showed decreased SN-38 glucuronidation activity. In our study, we compared the different variants of <i>UGT1A</i>s, such as <i>UGT1A1.6</i>, <i>UGT1A1.7, UGT1A1.27, UGT1A1.35, UGT1A7.3, UGT1A8.4, UGT1A10M59I</i>, and <i>UGT1A10T202I</i>, to determine the differences in the reduction of glucuronidation. …”
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72047
Heterogeneous response of SCN cells to the increasing concentration of fluo-4 AM in rat slice cultures of SCN:
Published 2010“…<p>The dependency of spontaneous [Ca<sup>2+</sup>]<sub>c</sub> spiking activity on the concentration (0.5–10 µM) of fluo-4 AM was examined. The mean frequency of calcium spikes was gradually increased in about 49% (A–B) of the active populations, had no systematic change in 35% (C–D), and decreased in 16% (E–F). …”
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72048
pri–miRNA abundance and Pol II occupancy at <i>MIR</i> genes in <i>pwr-1</i> and <i>pwr-2</i>.
Published 2013“…(C) Real-time RT-PCR analysis of other pri-miRNAs. A general decrease was observed in pri-miRNA transcript levels in both <i>pwr</i> alleles. …”
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72049
Model Studies of Methacrylate Chain Transfer Polymerization Mediated by Cationic Zirconocene <i>tert</i>-Butyl Enolate
Published 2005“…In this case, a moderate decrease in the molecular weight of the PMMAs is observed. …”
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72050
Data_Sheet_1_Estrogen Regulates Glucose Metabolism in Cattle Neutrophils Through Autophagy.ZIP
Published 2021“…<p>Hypoglycemia resulting from a negative energy balance (NEB) in periparturient cattle is the major reason for a reduced glycogen content in polymorphonuclear neutrophils (PMNs). …”
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72051
Data_Sheet_1_Hesperetin but not ellagic acid increases myosin heavy chain expression and cell fusion in C2C12 myoblasts in the presence of oxidative stress.docx
Published 2024“…An oxidative stress-induced decrease in differentiation capacity of muscle satellite cells is a key factor in this process. …”
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72052
RER1 expression significantly reduces αSyn levels.
Published 2017“…(B) Wild type RER1 expression significantly decreased αSyn levels (mean, 87.8 ±7.1%), but expression of RER1Δ25 resulted in significantly smaller effects on levels of αSyn (mean, 24.3 ±10.6%) (*p<0.05, **p<0.01; F<sub>2,6</sub> = 17.31, p = 0.0032) (n = 5/control, n = 7/RER1, n = 3/ RER1Δ25) in HEK293. …”
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72053
RT-qPCR quantification of the expression of <i>Lin28B</i> in peripheral blood monoculear cells.
Published 2013“…(Bar: mean; Black dot: undetectable) (<b>A</b>). Patients with recurrent HCC had significantly higher expression levels of <i>Lin28B</i> than patients without recurrent HCC. …”
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72054
H3K27me3 levels show differences across SMN differentiation in <i>Suz12GT</i> cells compared to wt cells.
Published 2014“…Day 0 (ESC) is at top, while day 5 SMN is shown at bottom. (<b>E</b>) H3K27me3 and H3K4me3 ChIP-seq tracks for <i>Gata6</i> promoter (left); <i>Bmp2</i> promoter (middle); and the <i>HoxA</i> cluster (right) show that H3K27me3 levels change (increase, decrease, or stay the same, depending upon locus) in <i>Suz12<sup>GT</sup></i> cells upon differentiation. …”
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72055
DataSheet_1_Pressurized intraperitoneal aerosolized chemotherapy (PIPAC) experience in patients with recurrent low grade serous ovarian carcinoma (LGSOC): sub-cohort report of phas...
Published 2024“…This analysis describes the outcomes of a sub-cohort of four LGSOC patients treated with IP cisplatin 10.5 mg/m<sup>2</sup>, doxorubicin 2.1 mg/m<sup>2</sup> PIPAC q4-6 weeks. …”
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72056
Example of staircases leading to threshold calculation.
Published 2013“…Each point represents the distance, in u′v′ units, between the chromaticity points that define the target and background. …”
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72057
Macrophages facilitate reactivation by the secretion of extracellular vesicles (EVs).
Published 2023“…However, M1 cells promote non-lytic exocytosis of VBNC cells without triggering extracellular reactivation, thereby prophylactically depleting a reservoir of dormant cells. It remains to be elucidated how the phagolysosome counteracts the capacity of B5/derivs. to reactivate intracellular VBNC cells and how M1 cells inhibit reactivation of extracellular VBNC cells (question marks).…”
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72058
Effect of <i>LipB</i> Disruption on Lipoic Acid Levels and PDH-E2 Lipoylation
Published 2007“…<div><p>(A) WT 3D7 and <i>LipB</i>KO mutants were analysed for their LA content. …”
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72059
DataSheet2_PK-PD integration of enrofloxacin and cefquinome alone and in combination against Klebsiella pneumoniae using an in vitro dynamic model.ZIP
Published 2023“…The dynamic time-kill curves indicated that enrofloxacin and cefquinome had bactericidal and bacteriostatic activities, respectively at ≥1.5 mg/L (single-dose) and 4 mg/L (8 h split-dose) causing a decrease in bacterial counts of ≥4.45 and >2 log<sub>10</sub> CFU/mL. …”
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72060
DataSheet1_PK-PD integration of enrofloxacin and cefquinome alone and in combination against Klebsiella pneumoniae using an in vitro dynamic model.ZIP
Published 2023“…The dynamic time-kill curves indicated that enrofloxacin and cefquinome had bactericidal and bacteriostatic activities, respectively at ≥1.5 mg/L (single-dose) and 4 mg/L (8 h split-dose) causing a decrease in bacterial counts of ≥4.45 and >2 log<sub>10</sub> CFU/mL. …”