<b>The loss of insulin-positive cell clusters precedes the decrease of islet frequency and beta cell area in type 1 diabetes</b> by Denise M. Drotar (21679539)

“…The majority of functional beta cell mass is typically lost within months to years of disease diagnosis, but the timing and nature of this loss, particularly in early disease stages, remain unclear. We developed a whole-slide scanned image (WSI) analysis pipeline for semi-automated quantitation of endocrine areas, islet frequencies, inter-islet distances, and endocrine object size distribution in 145 human pancreata from 60 non-diabetic (ND), 19 single autoantibody positive (sAAb+), 10 multiple autoantibody positive (mAAb+), 16 recent-onset (0-1 year duration), 23 medium-duration (1-7 years), and 17 long-duration type 1 diabetes (7+ years) donors. …”

Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio by Jani Luukkonen (4339744)

“…The TRAcP 5B/5A ratio was decreased in RA and correlated negatively with the amount of phospho-OPN (p<0.05). …”

Table_2_Decrease of Clone Diversity in IgM Repertoires of HBV Chronically Infected Individuals With High Level of Viral Replication.pdf by Binbin Hong (9989819)

“…To investigate the characteristics of antibody repertoires in patients with chronic HBV infection, we performed Illumina sequencing and IMGT/HighV-QUEST analysis of B lymphocytes from healthy adults and the HBV carriers with high or low level of viral replication. …”

Table_4_Decrease of Clone Diversity in IgM Repertoires of HBV Chronically Infected Individuals With High Level of Viral Replication.pdf by Binbin Hong (9989819)

“…To investigate the characteristics of antibody repertoires in patients with chronic HBV infection, we performed Illumina sequencing and IMGT/HighV-QUEST analysis of B lymphocytes from healthy adults and the HBV carriers with high or low level of viral replication. …”

Table_3_Decrease of Clone Diversity in IgM Repertoires of HBV Chronically Infected Individuals With High Level of Viral Replication.pdf by Binbin Hong (9989819)

“…To investigate the characteristics of antibody repertoires in patients with chronic HBV infection, we performed Illumina sequencing and IMGT/HighV-QUEST analysis of B lymphocytes from healthy adults and the HBV carriers with high or low level of viral replication. …”

24 h fasting decreases mARC protein levels and <i>N</i>-reductive activity in mice. by Heyka H. Jakobs (619421)

rVλ6Wil fibrils cause a decrease in cardiomyocytes MTT reduction without inducing cell death. by Helen P. McWilliams-Koeppen (116503)

“…(C) Cell number, quantified using crystal violet (black) did not decrease over 72 h of incubation with 1 μM rVλ6Wil fibrils despite a decrease in MMT reduction (grey; n = 3 samples per time point). …”

Transcriptional and translational markers of syncytialization and biochemical differentiation are significantly decreased by rotenone. by O’Llenecia S. Walker (8486163)

RUE decreases the level of alcohol-induced liver damage markers. by Jeong Hoon Pan (844624)

<i>Cdkl5</i> -/Y mice show an increased freezing time and a decreased distance traveled during the pretone period in the altered context. by Kosuke Okuda (5150393)

“…<i>Cdkl5</i> -/Y mice show a significantly decreased distance traveled in response to the first footshock (p = 0.0158) compared with control mice. …”

Removal of the A-B linker did not decrease PIP₂ affinity. <i>A.-</i> by Paloma Aivar (124885)

Stromal Expression of Decorin, Semaphorin6D, SPARC, Sprouty1 and Tsukushi in Developing Prostate and Decreased Levels of Decorin in Prostate Cancer by Alexander Henke (145303)

“…In embryonic and perinatal rats Decorin, Semaphorin6D, SPARC, Spry-1 and Tsukushi were expressed with varying distribution patterns throughout the mesenchyme at E17.5, E19.5, P0.5 and P6.5. In P28 and adult prostates there was either a decrease in the expression (Semaphorin6D) or a switch to epithelial expression of SPARC, and Spry-1, whereas Decorin and Tsukushi were specific to mesenchyme/stroma at all ages. …”

S1 File - by Yonghui Zhang (279832)

Subjects:

Experiment 1: Comparison of effort and delay discounting. by Miriam C. Klein-Flügge (713481)

“…The sigmoidal model was included because it fulfills two particular features: it can obtain initially concave shapes, in line with work showing that the sense of effort increases as a power function of the target force with decreasing sensitivity at lower effort levels; and it entails a turning point after which effort discounting becomes progressively less steep. …”

The BMP pathway decreases the ability of colonocytes to grow without anchoring. by Jacques Dupuy (6670244)

Decreased neutrophil levels in HIF^C mice correlates to decreased production of CXCL1 and not migration defects. by Kelly M. Shepardson (404375)

Supplementary Material for: Decreased Blood Flow after Sorafenib Administration Is an Imaging Biomarker to Predict Overall Survival in Patients with Advanced Hepatocellular Carcino... by Arizumi T. (3588833)

“…<b><i>Results:</i></b> Statistically significant differences in OS were observed among the three groups (p < 0.001). A decrease or disappearance of arterial enhancement was significantly associated with improved OS compared to patients with no change in arterial enhancement; the median OS was 19.9 months (95% confidence interval, CI, 16.4-24.5 months) and 6.0 months (95% CI, 4.0-8.8 months), respectively (p < 0.001). …”

(R+S) and (R)-albuterol decrease NF-κB activity by Marcela A Ferrada (41716)

“…After transfection, (R)-albuterol (R), (S)-albuterol (S), or racemic albuterol (R+ S) were added to cells pre-activated with (ConA, 5 μg/ml) and (PMA, 100 ng/ml) (CP) and then treated with (R)-, (S)-, or (R+S)-albuterol (Fig. 6). …”

Surveillance of HIV Transmitted Drug Resistance in Latin America and the Caribbean: A Systematic Review and Meta-Analysis by Santiago Avila-Rios (3160959)

Subjects:

Video5_Aging, not Parkinson’s disease, decreases a recalibration of body ownership caused by vision-respiratory interaction.MP4 by Daiki Shoji (18283906)