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Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on β-Adrenergic cAMP Signals
Published 2009“…The inotropic response to maximal β-adrenergic stimulation was reduced by ≈54% in isolated hypertrophied hearts, along with a ≈32% decrease in subsarcolemmal cAMP levels in hypertrophied myocytes. …”
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Decreased phosphodiesterase activities in cardiac hypertrophy
Published 2007“…Cyclic nucleotide-gated (CNG) channels were used to monitor cAMP. The whole cell patch-clamp technique was used to record the associated CNG current (ICNG) and ICa,L. …”
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Analysis of Diabetes Apps to Assess Privacy-Related Permissions: Systematic Search of Apps
Published 2021“…Accordingly, the availability of mobile apps for diabetes has been steadily increasing. Most of the previous reviews of diabetes apps have focused on the apps’ features and their alignment with clinical guidelines. …”
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Content Analysis of Apps for Growth Monitoring and Growth Hormone Treatment: Systematic Search in the Android App Store
Published 2020“…The increased demand for and availability of mobile health apps highlights the importance of regular publication of reviews to identify potential areas of unmet needs and concern. …”
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Predictors of mortality and morbidity in critically ill COVID‐19 patients: An experience from a low mortality country
Published 2022“…<h3>Background and Aims</h3><p dir="ltr">Clinical characteristics and factors associated with mortality in patients admitted to the intensive care unit (ICU) in countries with low case fatality rates (CFR) are unknown. We sought to determine these in a large cohort of critically ill COVID-19 patients in Qatar and explore the early mortality predictors. …”
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Can "Whatsapp" be the new luxury "app"? (c2018)
Published 2018“…This movement came complementary to the increase in the number of active WhatsApp users especially in the MENA region. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”
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Who Uses Mhealth? User Archetypes for Physical and Mental Health Apps
Published 2023“…Further, with these findings, apps can be tailored to optimize user experience and satisfaction which may help to increase user retention. …”
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Subsarcolemmal cAMP signals monitored by cyclic nucleotide gated channels in hypertrophied cardiac myocytes
Published 2005“…Cumulative concentrationresponse curve to the non-selective E-adrenergic agonist isoprenaline (Iso) indicated a 33% decrease of the maximal cAMP accumulation produced by Iso while the effect of the hydrosoluble forskolin analog, L-858051 at a saturating concentration (100 µM) was unchanged between the two groups. …”
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A review of mobile chatbot apps for anxiety and depression and their self-care features
Published 2021“…Anxiety and depression chatbot apps have the potential to increase the capacity of mental health self-care providing much needed low-cost assistance to professionals.…”
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Deep Learning for Aspect-Based Sentiment Analysis of Government Mobile Apps Reviews
Published 2018“…The number of smartphone users in the United Arab Emirates (UAE) has increased by 25% in the last four years (Statista.Com 2018c). …”
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A case of cat-scratch disease with unusual ophthalmic manifestations
Published 2012“…We report a case of cat-scratch disease with unusual posterior segment manifestations. …”
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Forecast of the outbreak of COVID-19 using artificial neural network: Case study Qatar, Spain, and Italy
Published 2021“…The model sensitivity was analyzed using the root mean square error (RMSE), the mean absolute percentage error and the regression coefficient index R2, which yielded highly accurate values of the predicted correlation for the infected and dead cases of 0.99 for the dates considered. The verified and validated growth model of COVID-19 for these countries showed the effects of the measures taken by the government and medical sectors to alleviate the pandemic effect and the effort to decrease the spread of the virus in order to reduce the death rate. …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). …”
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Fanconi–Bickel Syndrome: A Review of the Mechanisms That Lead to Dysglycaemia
Published 2020“…Missense, nonsense, frame-shift (fs), in-frame indels, splice site, and compound heterozygous variants have all been identified in SLC2A2 gene of FBS cases. Approximately 144 FBS cases with 70 different SLC2A2 gene variants have been reported so far. …”
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