Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection? by Abu Saleh Md Moin (6189512)

“…The Renin-Angiotensin System (RAS) is activated in type 2 diabetes (T2D); therefore, the aim of this study was to determine if hypoglycaemia-induced stress in T2D would potentiate serum NRP1(sNRP1) levels, reflecting an increased risk for SARS-CoV-2 infection.</p><h3>Methods</h3><p dir="ltr">A case-control study of aged-matched T2D (n = 23) and control (n = 23) subjects who underwent a hyperinsulinemic clamp over 1-hour to hypoglycemia(<40mg/dl) with subsequent timecourse of 4-hours and 24-hours. …”

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
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The emergence of new SARS-CoV-2 variant (Omicron) and increasing calls for COVID-19 vaccine boosters-The debate continues by Naushad Ahmad Khan (6406973)

“…The Delta variant was reported to have increased transmissibility, higher viral load [4] and high rates of reinfection [5]. …”

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”

Increased complications of COVID-19 in people with cardiovascular disease: Role of the renin–angiotensin-aldosterone system (RAAS) dysregulation by Robin Augustine (3976964)

SARS-CoV-2 Variants in Lebanon by Al Kodsi, Ibrahim

“…Variants of concern (VOC) included Alpha, Beta, Delta, Gamma, and most recently Omicron. Co-infections of SARS-CoV-2 with influenza viruses were detected and led to increased infectivity and SARS-CoV-2 viral load. …”
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Polarimetric SAR Speckle Reduction by Hybrid Iterative Filtering by Yahia, Mohamed

“…Speckle filtering in synthetic aperture radar polarimetry (PolSAR) is essential for the extraction of significant information. …”
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Polarimetric SAR Image Filtering by Infinite Number of Looks Prediction Technique by Yahia, Mohamed

“…Speckle filtering in synthetic aperture radar (SAR) and polarimetric SAR (PolSAR) images is indispensable before the extraction of the useful information. …”
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Addressing bias in the definition of SARS-CoV-2 reinfection: implications for underestimation by Hiam Chemaitelly (439114)

“…<h3>Introduction</h3><p dir="ltr">Reinfections are increasingly becoming a feature in the epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. …”

SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs by Raed Shalaby (3756112)

SARS-CoV-2 Infection and Smoking: What is the association? A brief review by Ishita, Gupta

“…Smoking has been shown to enhance the expression of the angiotensin-converting enzyme-2 (ACE-2) and transmembrane serine protease 2 (TMPRSS2) key entry genes utilized by SARS-CoV-2 to infect cells and induce a ‘cytokine storm’, which further increases the severity of COVID-19 clinical course. …”
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Decreased phosphodiesterase activities in cardiac hypertrophy by Abi-Gerges, A.

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Vulnerabilities of the SARS-CoV-2 Virus to Proteotoxicity—Opportunity for Repurposed Chemotherapy of COVID-19 Infection by Maryam S. Al-Motawa (9501818)

“…A strategy for improved drug therapy is to increase levels of endogenous reactive metabolites for selective toxicity to SARS-CoV-2 by preferential damage to the viral proteome. …”

A genetically encoded BRET-based SARS-CoV-2 Mpro protease activity sensor by Anupriya M. Geethakumari (17052375)

“…<p dir="ltr">The main protease, M^pro, is critical for SARS-CoV-2 replication and an appealing target for designing anti-SARS-CoV-2 agents. …”

YOLO-SAIL: Attention-Enhanced YOLOv5 With Optimized Bi-FPN for Ship Target Detection in SAR Images by Prabu Selvam (22330264)

“…It has recently become increasingly popular to apply deep learning algorithms to the identification of ships in SAR images. …”

Food purchase and eating behavior during the COVID-19 pandemic: A cross-sectional survey of Russian adults by Tarek Ben Hassen (15742605)

“…Indeed, the survey results suggested (i) a change in the modality of acquiring food, consumers reduced the number of shopping trips and buying more on each trip to minimize store visits; (ii) a surge of stockpiling of non-perishable food items; (iii) a shift toward healthier diets; (iv) an increase in culinary capabilities; (v) a decrease of food waste. …”

A multi-targeted approach to identify potential flavonoids against three targets in the SARS-CoV-2 life cycle by Sanjay Kumar (8853)

“…To identify the most promising bioactive flavonoids against the SARS-CoV-2, this article screened a virtual library of 46 bioactive flavonoids against three promising targets in the SARS-CoV-2 life cycle: human TMPRSS2 protein, 3CLpro, and PLpro. …”

SARS‐CoV‐2 infection and effects of age, sex, comorbidity, and vaccination among older individuals: A national cohort study by Mai A. Mahmoud (9620657)

“…Risk of infection varied minimally by age and sex but increased significantly with coexisting conditions. …”

SARS‐CoV‐2 omicron variant may present with severe sickle cell painful crisis: A report of two cases by Elrazi Ali (14777284)

“…Patients with sickle cell disease infected with SARS-CoV-2 are reported to have increased risk for hospitalization, thrombosis, and other complications compared with non-sickle cell patients. …”

Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 Cohort by Muneerah Smith (12542939)

“…As expected, patients with severe disease showed significantly higher antibody titers and interestingly also had significantly broader epitope coverage. A significant increase in antibody titer and epitope coverage was observed with increasing age, in both mild and severe disease, which is promising for vaccine efficacy in older individuals. …”