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Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart
Published 2022“…Aim: The influence of the physiochemical properties of dendrimer nanoparticles on cardiac contractility and hemodynamics are not known. Herein, we investigated (a) the effect of polyamidoamine (PAMAM) dendrimer generation (G7, G6, G5, G4 and G3) and surface chemistry (-NH2, -COOH and -OH) on cardiac function in mammalian hearts following ischemia-reperfusion (I/R) injury, and (b) determined if any PAMAM-induced cardiotoxicity could be mitigated by Angiotensin-(1-7) (Ang-(1-7), a cardioprotective agent. …”
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322
Investigation Into the Effects of Non-Linear Loading of Domestic Power Network on Home Appliances
Published 2016“…The motor is rated for 110V rms, 1500 rpm and 0.5 HP. The reference of the converter is generated by adding 3rd and 5th harmonic component to the fundamental component. …”
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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2...
Published 2024“…Estimates reported represent the mean value across 500 draws from the estimate's distribution, with 95% uncertainty intervals (UIs) calculated as the 2·5th and 97·5th percentile values across the draws. …”
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Methylmercury, Trace Metals, Organotins and Their Effects on the Qatari Mangrove Shrimp, Palaemon khori
Published 2022“…Aneuploidy was reported in all treatments and control ranging from 5% to 19% at week four and from 7% to 21% at week eight. …”
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Algal-algal bioflocculation enhances the recovery efficiency of Picochlorum sp. QUCCCM130 with low auto-settling capacity
Published 2023“…QUCCCM50 presenting a cell size of ?2 ?m, ?5 ?m, and ?15 ?m, respectively, were selected to be subjected to the harvesting optimisation experiments. …”
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327
The response of culturally important plants to experimental warming and clipping in Pakistan Himalayas
Published 2021“…The relative effects of climate warming with grazing on medicinally important plants are not fully understood in Hindukush-Himalaya (HKH) region. Therefore, we combined the indigenous knowledge about culturally important therapeutic plants and climate change with experimental warming (open-top chambers) and manual clipping (simulated grazing effect) and compared the relative difference on aboveground biomass and percent cover of plant species at five alpine meadow sites on an elevation gradient (4696 m-3346 m) from 2016- 2018. …”
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328
Algal-algal bioflocculation enhances the recovery efficiency of Picochlorum sp. QUCCCM130 with low auto-settling capacity
Published 2023“…QUCCCM50 presenting a cell size of ∼2 μm, ∼5 μm, and ∼15 μm, respectively, were selected to be subjected to the harvesting optimisation experiments. …”
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329
Location privacy preservation in secure crowdsourcing-based cooperative spectrum sensing
Published 2016“…In this paper, we focus on two major problems. The first problem is the localization preservation of the secondary users. …”
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Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
Published 2024“…In cardiac muscle, CaM modulates directly or indirectly the activity of several proteins that play a key role in excitation-contraction coupling (ECC), such as ryanodine receptor type 2 (RyR2), l-type Ca2+ (Cav1.2), sodium (NaV1.5) and potassium (KV7.1) channels. Many recent clinical and genetic studies have reported a series of CaM mutations in patients with life-threatening arrhythmogenic syndromes, such as long QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CPVT). …”
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Sorption of benzene and naphthalene on (semi)-arid coastal soil as a function of salinity and temperature
Published 2018“…The sorption of naphthalene was not affected by the change in salinity but increased by 18% when the temperature decreased from 35 to 5 �C. A sorption kinetic model was also applied to define the sorption behavior of benzene and naphthalene for the coastal soil collected in Qatar and the best fits were achieved with the Langmuir sorption isotherm.…”
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Therapeutic outcomes and biodistribution of gold nanoparticles in collagen-induced arthritis animal model
Published 2022“…CIA rats were then divided into five groups: CIA model (positive control), AuNPs treated- (sphere shape with size: 5, 25, and 75 nm), and methotrexate (MTX)-treated-rats. …”
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Burden of disease attributable to suboptimal diet, metabolic risks and low physical activity in Ethiopia and comparison with Eastern sub-Saharan African countries, 1990-2015: findi...
Published 2018“…While the age-adjusted proportion of all-cause mortality attributable to CMU decreased significantly between 1990 and 2015, it increased from 10.8% [95% UI: 8.8-13.3] to 14.5% [95% UI: 11.7-18.0] for dietary risks and from 17.0% [95% UI: 15.4-18.7] to 24.2% [95% UI: 22.2-26.1] for metabolic risks. …”
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Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells.
Published 2024“…We assessed the impact of insulin resistance (IR) on metabolic pathways, focusing on genes linked to branched-chain amino acid metabolism, detoxification, and chemotaxis. …”
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Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
Published 2024“…For adults, we report the individual and combined prevalence of underweight (BMI <18·5 kg/m2) and obesity (BMI ≥30 kg/m2). …”
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