STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS by AL-SADEQ, DUAA WALID

“…In contrast, all the other CBS mutation studies did not fully retain heme and, when compared to the wild-type enzyme, exhibited more significant impairments in both the canonical cystathionine synthesis and the alternative H2S-producing reactions. This reduced activity is consistent with both in vitro and in silico evidence, which indicates that the studied CBS mutations, except p.K72I, significantly decrease the overall protein's stability, which may represent the underlying cause of their pathogenicity. …”
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Effect of hyperlipidemia on ketoconazole-midazolam drug-drug interaction in rat by Hamdy, D. A.

“…Normolipidemic and hyperlipidemic rats were administered a single intravenous dose of MDZ (5 mg/kg) with or without a single oral dose of racemic KTZ (40 mg/kg). …”
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Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy... by Hmwe Hmwe, Kyu

“…FindingsIn 2021, diarrhoeal diseases caused an estimated 1·17 million (95% uncertainty interval 0·793–1·62) deaths globally, representing a 60·3% (50·6–69·0) decrease since 1990 (2·93 million [2·31–3·73] deaths). …”
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Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021 by Sirota, Sarah Brooke

“…The mortality rate of URIs in 2021 was 0·2 per 100 000 (0·1 to 0·5), a decrease of 64·2% (–84·6 to –43·4) from 1990, when the mortality rate was 0·7 per 100 000 (0·2 to 1·1). …”
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The Effects of Class IV Hemorrhagic Hypotensive Shock and Its Resuscitation with Fluids and Adjuvant Vasopressors or Cellular Energy Replenishment on the Splanchnic Microcirculatio... by Zakaria, El Rasheid

“…This was followed by phase-2 of uncontrolled hemorrhage as induced by transection of the splenic parenchyma at the two ends of the organ and severing one of the branches of the splenic artery. …”
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USING EMBEDDED MACHINE LEARNING IN THE PHYSICAL WORLD TO DETECT TOXICITY IN SPOKEN LANGUAGE by ABU NADA, AHLAM HUSNI

“…In our study, quantization demonstrated a significant reduction in model size by almost fourfold and a 3.3-fold decrease in RAM usage. The marginal average F1 score decrease was limited to only 1%. …”
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Low electro-synthesis potentials improve permselectivity of polymerized natural phenols in biosensor applications by Monti, Patrizia

“…Polymers were obtained by means of constant potential amperometry, instead of cyclic voltammetry, in order to achieve multiple polymerizations, hence decreasing the time of realization and variability. …”
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The status of forward osmosis technology implementation by Awad, Abdelrahman M.

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Radiofrequency Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation: Meta-analysis of Safety and Efficacy by Yi F.

“…Random effect summary estimates were calculated as standardized mean differences and odds ratios with 95% confidence intervals for continuous and binary outcomes. …”
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Modeling the influence of daily temperature and precipitation extreme indices on vegetation dynamics in Katsina State using statistical downscaling model (SDM) by Mohammad, Hadi Ahmad

“…The results indicate that the statistical downscaling model (SDSM) is performing satisfactorily in predicting maximum and minimum temperatures, along with precipitation, for the time horizon of the simulation. Mean precipitation of 1.98 mm (RCP2.6), 2.03 mm (RCP4.5), and 2.07 mm (RCP8.5) was revealed in the study area. …”
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Enhanced boron removal by electricity generation in a microbial fuel cell by Ping, Qingyun

“…In the post-treatment mode, the MFC removed 80–90% of boron and decreased the boron concentration from 20 to 2 mg L− 1 or from 5 to 1 mg L− 1, which meets the irrigation water requirement. …”
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Flight Scheduling in the Airspace by Msakni, Mohamed Kais

“…If this condition could not be satisfied, one of the flight will be delayed. This solution is undesirable for many reasons such as missing the connecting flight, decrease in the passengers' satisfaction, etc. …”
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Caffeine use or napping to enhance repeated sprint performance after partial sleep deprivation: Why not both? by Romdhani, Mohamed

“…CAF+N increased Pmax (P < .001, d = 1.5; d = 0.94), Pmin (P < .001, d = 2.79; d = 2.6), and Pmean (P < .001, d = 1.93; d = 1.79) compared with placebo and CAF, respectively. …”
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Box-Behnken approach for optimization of Cr(III) removal from a real tanning effluent using powdered marble by Boujelben, R.

“…The results showed that the maximum uptake (> 99%) was obtained at a chromium initial concentration of 0.758�g/L, pH = 5.0 and using 6% (w:v) of powdered marble. Adsorption isotherm was satisfactorily described by Langmuir model. …”
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A disease-modifying treatment for Alzheimer's disease: Focus on the trans-sulfuration pathway by Berry, Thomas

“…With the dysregulation of iron-sulfur cluster formation ACO1 will convert to IRP1 which will decrease the 2-oxglutarate synthesis dysregulating the citric acid cycle and also dysregulating iron metabolism. …”
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Modeling the influence of daily temperature and precipitation extreme indices on vegetation dynamics in Katsina State using statistical downscaling model (SDM) by Mohammad, Hadi Ahmad

“…The results indicate that the statistical downscaling model (SDSM) is performing satisfactorily in predicting maximum and minimum temperatures, along with precipitation, for the time horizon of the simulation. Mean precipitation of 1.98 mm (RCP2.6), 2.03 mm (RCP4.5), and 2.07 mm (RCP8.5) was revealed in the study area. …”
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Consumption of some food groups is associated with the risk of cardiovascular disease among Jordanians by Tayyem, Reema

“…Mean age of participants was 56.2+0.55 and 57.2+0.82 for males and females respectively. …”
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A Reverse MultipleChoice Based mLearning System by Karkar, AbdelGhani

“…For the multiple-choice questions, we start with the familiar multiple-choice format [1], which we call "Reverse Multiple-Choice Method" (RMCM). …”
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Effect of left atrial ligation-driven altered inflow hemodynamics on embryonic heart development: clues for prenatal progression of hypoplastic left heart syndrome. by Salman, Huseyin Enes

“…According to our CFD analysis, LAL results in an immediate decrease in the left AV canal WSS levels for 3.5-day (HH21) pre-septated hearts. …”
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Effect of outdoor temperature on the power-conversion efficiency of newly synthesized organic photosensitizer based dye-sensitized solar cells by Mehmood U.

“…The results indicate that DSSC shows power conversion efficiency of 2.58% at 25 °C under air mass (AM) 1.5 G illumination at 100 mW/cm2. …”
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