Apocynin and catalase prevent hypertension and kidney injury in Cyclosporine A-induced nephrotoxicity in rats. by Tan, Yong Chia

“…There is enhanced expression of nicotinamide adenine dinucleotide (NADPH oxidase) and therefore production of hydrogen peroxide (H2O2) during renal disease progression. This study investigated the effect of apocynin, an NADPH oxidase inhibitor and catalase, an H2O2 scavenger on Cyclosporine A (CsA) nephrotoxicity in Wistar-Kyoto rats. …”
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The effect of acute ophiobolin A treatment on HO-mediated inflammatory processes by Posa, Aniko

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Involvement of caveolae in hyperglycemia-induced changes in adiponectin and leptin expressions in vascular smooth muscle cells by Ola, El Atab

“…Rat aorta organ culture was used to investigate the effect of hyperglycemia on APN and leptin protein expression in vascular smooth muscle cells (VSMCs) using Western blot analysis and immunohistochemistry. Hyperglycemia lead to a significant increase in APN synthesis in VSMCs, mainly through caveolae, but this increase failed to provide vascular protection because of the decreased expression of APN receptors, especially AdipoR2, which was assessed by qPCR. …”
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Molecular properties prediction, anticancer and anti-inflammatory activities of some pyrimido[1,2-b]pyridazin-2-one derivatives by Zeiz, Ali

“…Introduction: The anticancer and anti-inflammatory activities of a novel series of eleven pyrimido[1,2-b]pyridazin-2-one analogues substituted at position 7 were assessed in the current study. …”
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Food purchase and eating behavior during the COVID-19 pandemic: A cross-sectional survey of Russian adults by Ben Hassen, Tarek

“…Indeed, the survey results suggested (i) a change in the modality of acquiring food, consumers reduced the number of shopping trips and buying more on each trip to minimize store visits; (ii) a surge of stockpiling of non-perishable food items; (iii) a shift toward healthier diets; (iv) an increase in culinary capabilities; (v) a decrease of food waste. …”
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Trends of use of SGLT2 inhibitors in Qatar by Zaghloul, Nancy

“…Background: Type 2 diabetes mellitus (T2DM) represents a growing health challenge in Qatar and worldwide. …”
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CD146, a novel target of CD44-signaling, suppresses breast tumor cell invasion. by Ouhtit, Allal

“…Our results revealed that CD44 activation could cause a substantial decrease of CD146 expression with an equally notable converse effect upon CD44-siRNA inhibition. …”
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Anticoagulant activity of cellulose nanocrystals from isora plant fibers assembled on cellulose and sio2 substrates via a layer-by-layer approach by Mohan T.

“…In this study, we report the isolation of cellulose nanocrystals (CNCs) from Isora plant fibers by sulfuric acid hydrolysis and their assembly on hydrophilic cellulose and silicon-di-oxide (SiO2) surfaces via a layer-by-layer (LBL) deposition method. …”
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Thermodynamic analysis of solar-driven chemical looping steam methane reforming over Cr2O3/Cr redox pair by Bhosale, Rahul

“…For this study, two process configurations are considered: a) CS process - Cr2O3/Cr based MR open process, and b) CSH process- Cr2O3/Cr based MR and WS semi-open process. …”
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Effects of covid-19 lockdown on physical activity, sedentary behavior, and satisfaction with life in Qatar: A preliminary study by Hermassi, Souhail

“…Life satisfaction decreased, with the score for “I am satisfied with my life” (ηp2 = 0.76, p < 0.001) decreasing from 28.1 ± 4.81 to 14.2 ± 6.41 arbitrary units (AU). …”
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Sol-gel derived CeO2-Fe2O3 nanoparticles: Synthesis, characterization and solar thermochemical application by Bhosale, Rahul R.

“…For the synthesis of CeO2-Fe2O3, cerium nitrate hexahydrate and iron nitrate nonahydrate were first dissolved in ethanol and then PO was added to this mixture as a proton scavenger to achieve the gel formation. …”
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Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus by Dimitrios, Patoulias

“…They have demonstrated1 that empagliflozin treatment resulted in a significant decrease in pulse pressure (PP), mean arterial pressure (MAP) and cardiac workload, compared with placebo; at week 12, placebo-adjusted mean changes from baseline were − 2.5 mmHg for PP, − 2.2 mmHg for MAP and − 315 mmHg x beats per minute (bpm) for cardiac workload (p < 0.0001 for all). …”
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Comparative skull analysis suggests species-specific captivity-related malformation in lions (Panthera leo) by Saragusty, Joseph

“…Lion (Panthera leo) populations have dramatically decreased worldwide with a surviving population estimated at 32,000 across the African savannah. …”
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Effects of gamma radiation on the activity of the mosquito culex pipiens L. II. Effects on the sexual vitality of the mosquito by El Banby, M. A. [محمد البنبي]

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Structural and mechanical characterization of stir cast Al–Al2O3–TiO2 hybrid metal matrix composites by Ahamad, N.

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Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach by P., Sneha

“…Two arginine residues (131 and 203) in the HNF1A protein are highly conserved residues and contribute to the function of the protein. …”
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Absorption of CO2 in aqueous blend of methyldiethanolamine and arginine by Talkhan, Ahmed Gomaa

“…However, for CO2 partial pressure of above 20 kPa, the addition of Arg caused a decrease in the solubility of CO2. …”
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Effect of Bariatric Surgery on Serum Amyloid A Protein: a Systematic Review and Meta-analysis by Jamialahamdi, Tannaz

“…Results: Meta-analysis of 11 clinical studies (n = 394 individuals) confirmed a significant reduction in SAA following bariatric surgery (SMD: − 0.971, 95% CI: − 2.721, 0.779, p < 0.001). …”
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Heat-stress-induced changes in enzymatic antioxidant activities and biochemical processes in bell pepper (Capsicum annuum L.) seedlings by Bello, Adewale Suraj

“…At 40 and 32 °C, HS led to a decrease in chlorophyll a (4.327 mg g–1 FW), b (1.710 mg g–1 FW), total chlorophyll (5.202 mg g–1 FW), and total carotene (1.092 mg g–1 FW) compared to the control at 25 °C (chlorophyll a 5.383 mg g–1 FW, chlorophyll b 2.358 mg g–1 FW, total chlorophyll 6.692 mg g–1 FW, and total carotene 1.817 mg g–1 FW). …”
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Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation by El Hasasna, Hussain

“…Furthermore, we found that while both autophagy inhibitors abolished p38 phosphorylation, only CQ led to significant decrease in pERK1/2. Finally, RCE induced DNA damage and reduced mutant p53, two events that preceded autophagy. …”
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