MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels. حسب Gomes da Silva, Isaura Isabelle Fonseca

"…Rheumatoid arthritis (RA) is a well-known chronic inflammatory disorder. Two molecular players act in the inflammation balance of the disease: MyD88 (Myeloid differentiation primary response 88) is related to TLR (Toll-like receptors) response and promotes the formation of myddosome complex resulting in increased inflammation; IRAK3 (Interleukin-1 receptor associated kinase 3) acts suppressing the myddosome complex thus decreasing inflammation. …"
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Prospects Of Amino Acids And Ionic Liquids As Natural Gas Hydrate Inhibitors For Offshore Flow Assurance حسب Qureshi, M. Fahed Aziz

"…The results show that the selected amino acids and ionic liquids exhibit dual functional behaviour by providing the temperature shift of around 1.5-2.3 oC and delaying the hydrate formation time from 0.5-1.5 hr. …"
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Abnormal brain structure and behavior in MyD88-deficient mice. حسب Schroeder, Patricia

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Temporal cross talk between endoplasmic reticulum and mitochondria regulates oxidative stress and mediates microparticle-induced endothelial dysfunction حسب Safiedeen, Zainab

"…Results: Here, we show that both types of MPs increased expression of endoplasmic reticulum (ER) stress markers XBP-1, p-eIF2alpha and CHOP and nuclear translocation of ATF6 on human aortic endothelial cells. …"
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Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021 حسب Comfort, Haley

"…The global neonatal mortality rate in 2021 was 17·1 (14·8–19·9) per 1000 livebirths, corresponding to 2·19 million (1·90–2·55) neonatal deaths. The estimated number of stillbirths occurring at 20 weeks' gestation or longer decreased from 5·08 million (95% UI 4·07–6·35) in 1990 to 3·04 million (2·61–3·62) in 2021, corresponding to a 39·8% (31·8–48·0) reduction, which lagged behind a global improvement in neonatal deaths of 45·6% (36·3–53·1) for the same period (down from 4·03 million [3·86–4·22] neonatal deaths in 1990). …"
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Bioactive Components from Ginger, Tea and Apple Prevent Protein Glycation by Trapping Methylglyoxal with Potential in Alleviation of Diabetic Complications حسب Sang, Shengmin

"…In diabetes, formation of AGEs occurs at a higher rate when compared to non-diabetic normal individuals. …"
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Changing Paradigm in The Global LNG Market: Opportunities And Risks For Major Suppliers in The Gulf Region حسب Sung, Jinsok

"…At the same time, share of Japan and South Korea, two of the largest LNG importers in the global LNG market is decreasing. …"
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The Expression of TBC1 Domain Family, Member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane حسب Rizk, Nasser M

"…Sulforaphane (SFN) has been suggested as a new potential anti-diabetic compound acting by reducing blood glucose levels through mechanisms not fully understood (1). …"
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Synthesis and Pharmacological Evaluation of Different Piperine Analogs for Therapeutic Potential to Prevent ER Stress حسب Hammad, Ayat Samir

"…Our findings indicate that exposure to tunicamycin (0.5 µg/mL) for 2 hours induces the expression of GRP78 and CHOP, and causes a significant reduction in renal cell viability. …"
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Simulation-Based Parametric Study for the Hybrid Superplastic Forming of AZ31 حسب Al-Abtaha, Fatima Ghassan

"…A two-dimensional finite element model is used to simulate the process. …"
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Dysregulated Metabolic Pathways in Subjects with Obesity and Metabolic Syndrome حسب Mir, Fayaz Ahmad

"…We measured 1069 serum metabolites and correlated them to clinical features. Results: A total of 83 metabolites, mostly lipids, were significantly different (p < 0.05) between the two groups. …"
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Radiation-free imaging for distal hole targeting in Intramedullary nailing حسب Abu-Gaoud, Monther Ghafel

"…The first two problems are resolved by using a contrast agent, Copper (II) Sulfate (CuSO4), which decreases the relaxation time by 6-7 times. …"
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Salinity inhibits seed germination of perennial halophytes Limonium stocksii and Suaeda fruticosa by reducing water uptake and ascorbate dependent antioxidant system حسب Hameed, Abdul

"…Germination and hydration of the seeds of both species decreased with increases in NaCl concentration. CAT and GPX activities were higher while APX, AsA and GSH decreased in salt stressed seeds compared to water-imbibed seeds. …"
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STANDARDIZATION OF AN IN VITRO MODEL OF DIABETIC NEPHROPATHY IN RENAL TUBULAR CELLS AND INVESTIGATION OF THE ROLE OF ALDOSE REDUCTASE PATHWAY IN HIGH GLUCOSE-INDUCED RENAL CELL INJ... حسب El Gamal, Heba

"…The expression of aldose reductase, markers of ER stress such as GRP78 and CHOP, and activation of Akt and ERK1/2 signaling has been measured using western blotting. …"
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Changes in plant composition and diversity in an alpine heath and meadow after 18 years of experimental warming حسب Alatalo, Juha M.

"…A potential driver for the changes in the meadow may be decreased soil moisture caused by long-term warming.…"
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Short-term effects of warming treatment and precipitation manipulation on the ecophysiological responses of pinus densiflora seedlings حسب Yun, Soon Jin

"…The aim of this study was to investigate the short-term effects of warming treatment and precipitation manipulation on the growth, photosynthetic rate, and chlorophyll content of Pinus densiflora seedlings based on a climate change scenario in Korea. Two year old P. densiflora seedlings were planted in a nursery in April 2013. …"
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Impact of outdated CSI on the secrecy performance of dual-hop networks using cooperative jamming حسب Mallat, Walid

"…We study the secrecy performance of partial relay selection with outdated channel state information (CSI). We propose a system secrecy where two sources and destination simultaneously transmit the legitimate and the jamming signal respectively. …"
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Metabolic consequences of obesity on the hypercoagulable state of polycystic ovary syndrome. حسب Moin, Abu Saleh Md

"…Eight pro-coagulation proteins were elevated in PCOS: plasminogen activator inhibitor-1 (p < 0.0001), fibrinogen (p < 0.01), fibrinogen gamma chain (p < 0.0001), fibronectin (p < 0.01), von Willebrand factor (p < 0.05), D-dimer (p < 0.0001), P-selectin (p < 0.05), and plasma kallikrein (p < 0.001). However, two anticoagulant proteins, vitamin K-dependent protein-S (p < 0.0001) and heparin cofactor-II (p < 0.001) were elevated and prothrombin was decreased (p < 0.05). …"
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Event-triggered fault detection for discrete-time LPV systems حسب Golabi, Arash

"…It is shown that through two event-triggered data transmission mechanisms, the amount of data sent to the fault detection module is decreased significantly. …"
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Predicting Contemporary Volume with Historic Volume at Differential Price Level: Prospect Theory vs. Regret Aversion حسب El Khouri, Ritab

"…Regret aversion, on the other hand, explains why investors may have difficulty in realising gains as well as losses. A new methodology is used to examine the relationship between volume at a given point in time and volume that took place in the past at different stock price level. …"
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