Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Behavioral data. by Charmaine Y. Pietersen (37545)

“…Fear conditioning affects almost all of the behaviors including a decrease in resting duration (p = 0.0064; A), and increases in rearing duration (p = 0.0262; A), resting frequency (p<0.0001; B), and freezing duration (p = 0.0001; A) and frequency (p<0.0001; B). …”

Data_Sheet_1_Prednisolone in Dogs—Plasma Exposure and White Blood Cell Response.PDF by Carl Ekstrand (10944231)

“…The objective of this study was to quantitatively characterize the concentration-effect relationship for prednisolone in dogs on neutrophil and lymphocyte trafficking and cortisol suppression. Nine beagles, 2–12 years old and part of a group for teaching/research were used in a 4-way crossover experiment including two treatments, active or placebo, administered either per os (PO) or intravenously (IV). …”

Frequency distributions of the <i>γ</i> values for the parameter sets that yield circadian oscillation. by Kazuhiro Maeda (182174)

“…<i>γ</i> is the quantitative balance of the <i>X</i> and <i>Y</i> feedback loops, which is defined by: , where [<i>X</i>(<i>nuc</i>)]<i>_mean</i> indicates the mean concentration for <i>X</i> in nucleus and [<i>Y</i>(<i>nuc</i>)]<i>_mean</i> that for <i>Y</i> in nucleus. …”

The strength of the signal at binding sites depends on the free energy of repressor binding. by Rosalind Wenshan Pan (17174817)

“…Δ<i>ε</i>_pd is fixed at -5 <i>k</i>_<i>B</i><i>T</i>, RNAP copy number is fixed at 1000, and repressor copy number is fixed at 10. …”

Evolutionary Conservation and Diversification of Puf RNA Binding Proteins and Their mRNA Targets by Gregory J. Hogan (160970)

“…Focusing on Puf proteins and their targets across 80 fungi, we constructed a parsimonious model for their evolutionary history. …”

DataSheet1_Characteristics of adverse reactions of three anti-glioma drugs in WHO-VigiAccess.ZIP by Huadong Ke (19937268)

“…The analysis revealed that the ten most frequently reported AEs included bone marrow suppression, myalgia, leukopenia, thrombocytopenia, nausea, vomiting, death, rhabdomyolysis, disease progression, and a decrease in neutrophil count. The five most common categories of AEs related to anti-glioma drugs were blood and lymphatic system diseases (20,233 cases, 15.2%), general disorders and administration site conditions (26,973 cases, 20.3%), gastrointestinal dysfunction (22,061 cases, 16.7%), necessitating further investigations (18,285 cases, 13.8%), and musculoskeletal and connective tissue diseases (30,695 cases, 23.1%). …”

Genome-Wide CRISPRi-Based Identification of Targets for Decoupling Growth from Production by Songyuan Li (6163535)

“…In total, we identify 1332 sgRNAs that simultaneously decrease growth and maintain or increase accumulation of GFP. …”

Integrated double signal amplification systems with ELISA assay for sensitive detection of tylosin in food by Shan Shan (396787)

“…Additionally, the established double signal amplification Bio-SA-HCR-ELISA was used for detecting TYL in milk and honey, the LOD of this method were 4.9 and 2.5 ng/mL, respectively.</p>…”

Roles of Cochaperones HOP and CHIP in KCNQ4 Biosynthesis. by Yanhong Gao (244711)

“…Over-expression of cochaperone HOP led to a significant increase, whereas over-expression of CHIP resulted in a marked decrease in total KCNQ4 level. <i>E. & F. Effects of siRNA knockdown of HOP or CHIP on total KCNQ4 level</i> HEK293T cells were transfected with 0.4 µg of pCMV6-XL5-HA-KCNQ4 (+) and various amount of siRNA as indicated. …”