Image_4_Bioactive metabolites of Streptomyces misakiensis display broad-spectrum antimicrobial activity against multidrug-resistant bacteria and fungi.jpeg by Rewan Abdelaziz (12961639)

“…Lung tissue in the pneumonia model showed a 2.20 log CFU/g significant decrease in the ursolic acid methyl ester-treated group in comparison to the control group. …”

Degradation Pathways of Ataxin-3-Induced Neurodegeneration by Julide Bilen (35807)

“…Genotypes (B) <i>EP1384; gmr-GAL4 UAS-SCA3trQ78 /+; UAS-DTS5/+</i> and (C) <i>w; gmr-GAL4 UAS-SCA3trQ78/+; UAS-DTS5/E213-1A.…”

Bufalin exhibited strong anti-osteosarcoma activity <i>in vivo</i>. by Xian-biao Xie (302694)

“…(B) A significantly decreased tumor weight at study termination, as compared to control or MTX-treated mice, was observed. …”

Metformin shows radioprotective effects <i>in vitro</i>. by Silvia Siteni (10344070)

“…Metformin 0.5 mM pre-treatment decreases the number of γH2AX foci in irradiated cells, compared to irradiated only controls. …”

Assessment of participation bias in cohort studies: systematic review and meta-regression analysis by Sérgio Henrique Almeida da Silva Junior (12739578)

“…Among the 2,964 initially identified, 50 were selected. The average proportion of participation was 64.7%. …”

Effect of acceptor membrane concentration on 12AS transfer from EgFABP1 to EPC/NBD-PC SUVs. by Jorge L. Porfido (118928)

“…Fatty acid transfer rates were directly monitored by the time-dependent decrease in anthroyloxy group fluorescence, as described in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0001893#s2" target="_blank">Materials and Methods</a>. …”

Histograms showing natural genetic variation of life history traits using adjusted means. by Marilyne Debieu (415078)

“…(b) Secondary dormancy (% of germination decrease per day): measured by the reduction in germination rate of fully after-ripened seed after a 6-week long exposure to 4°C in darkness. …”

Lack of ABCB1 or ABCC1 expression leads to impaired exploratory activity. by Toni Schumacher (325416)

“…Plotting the animals' course in the Y-maze, the running distance reveals a significant decrease in ABCB1- (−13%) and ABCC1- (−17%) deficient animals (A), while this parameter was only slightly, non-significantly decreased in ABCG2-deficient mice. …”

Effect of synergistic antimicrobial combinations on growth kinetics of MDR pathogens. by Amber Farooqui (315564)

“…Control organisms were grown in MH broth only. A 2Log₁₀ decrease at any time point from original CFU was considered as significant. …”

Scatter-plots representing the relative expression levels of 21 miRNAs. by Patrícia M. Pereira (156295)

“…<p>The relative expression of the 21 miRNAs that were deregulated are represented for normal cervix (red), CINI-cervical intraepithelial lesion grade I (green), CINIII-cervical intraepithelial lesion grade III (blue) and squamous cervical carcinoma (black) samples. <b>A</b>) 8 miRNAs that showed relative decrease in expression in the transition from normal cervix through premalignant dysplasia to cancer. …”

Percent changes (Δ-values) in regulator levels of Separase proteolytic activity after IM treatment when compared to the corresponding untreated cells.¹ by Wiltrud Haaß (312818)

“…1<p>for representative corresponding immunostained Western blots see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042863#pone-0042863-g005" target="_blank">Figure 5</a> panels B and C.…”

Increased spleen weight in myrAkt1 overexpressing animals is due to increased erythropoiesis. by Rebekah K. O’Donnell (286522)

“…The total number of TER119^hi cells in the bone marrow remained constant (<b>E</b>), but myrAkt1 animals displayed an increase in stages I and II with a complementary decrease in III (<b>F</b>) p<0.007.…”

CSF cytokine/chemokine levels that were more elevated in ADEM compared to EVE and anti-NMDAR E. by Kavitha Kothur (2502691)

“…<p>Th17 (IL-21, IL-17A) and Th2 (CCL17, and IL-4) related cytokine/chemokines showed statistically significant elevation in ADEM compared to both EVE and anti-NMDAR E. …”

Selection of EHEC proteins differentially abundant in the hemoglobin-positive (HB+) group versus the hemoglobin-negative (HB-) in vivo group. by Rembert Pieper (197697)

“…The statistical significance of the in vivo vs. the in vitro change and an observed increase ↑or decrease ↓ are also provided. Details are provided in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0066462#pone.0066462.s003" target="_blank">Dataset S2</a>.…”

Evidence that RA fails to regulate in an opposite fashion CER synthesis and SK activity in cells lacking endogenous RARα. by Giulia Somenzi (79002)

“…<p>A) Lack of endogenous RARα signaling (left) is demonstrated by lack of RA-induced transcription of the RARα target <i>RARβ2</i> (right). …”

Association between measures of metabolic traits and the rs6232 G-allele and the rs6235 C-allele of <i>PCSK1</i> among 6,039 treatment-naïve Danes. by Anette P. Gjesing (205277)

“…<p>Data are presented as mean ± SD and as effect sizes (95% CI) for traits following a normal distribution. Remaining traits are presented as median (inter-quartile range) and their effect sizes are presented as increase/decrease in percentage pr. allele in relation to the value of the major homozygous genotype. …”

Binaphthoquinones inhibit yeast respiratory growth by depolarizing the mitochondrial membrane. by Ashkan Emadi (248270)

“…The wild type yeast was treated at IC₅₀ concentrations of binaphthoquinones (1, 5 and 5µM of BiQ7, BiQ11 and BiQ3 respectively) for 2h and then incubated with rhodamine 123. The peak shift toward the left represents a decrease of fluorescence signal of rhodamine 123 in the yeast, indicating the loss of mitochondrial membrane potential in the presence of BiQs as compared to no drug (DMSO) control.…”

Patterns of species richness from range overlap raster data from 10,446 species. by Jonnell C. Sanciangco (152156)

“…<p>Each change in color represents an increase or decrease of 82 species (40 total classes or a 2.5% change per class). …”

The SPR analysis of SECRET-CX3CL1 interaction in the presence of heparin. by Xiaoguang Xue (211883)

“…<p>(A) Sensorgrams of passing CX3CL1 pre-incubated with an increased concentration of heparin (sodium salt, molecular weight ∼15 KD) (0, 0.125, 0.25, 0.5, 1, 2, and 4 mg/ml) through the CM5 chip surface immobilized with the SECRET domain. …”

Total number of exacerbations per year in each class of exacerbation the year before and the year after Ig treatment. by Juthaporn Cowan (825122)

“…The overall decrease in number of exacerbations ignoring the clustering of events among patients was an 84.9% reduction in moderate AECOPD events, 91.7% in severe AECOPD events and 86.2% in moderate or severe AECOPD.…”