Table_2_Sub-MIC antibiotics increased the fitness cost of CRISPR-Cas in Acinetobacter baumannii.docx by Ting Yu (156230)

“…Type I-Fb and Type I-Fa are two subtypes of CRISPR-Cas systems that were found in A. baumannii, and the I-Fb CRISPR-Cas system regulates antibiotic resistance in A. baumannii. …”

Induction of miR-96 by Dietary Saturated Fatty Acids Exacerbates Hepatic Insulin Resistance through the Suppression of INSR and IRS-1 by Won-Mo Yang (3609002)

“…Diets rich in saturated fatty acids (SFA) exacerbate obesity and hepatic steatosis, which increase the risk of hepatic insulin resistance and type 2 diabetes (T2DM). Although microRNAs (miRNAs) play an important role in a range of biological processes, the implications of SFA-induced miRNAs in metabolic dysregulation, particularly in the pathogenesis of hepatic insulin resistance, are not well understood. …”

Copy-the-majority of instances or individuals? Two approaches to the majority and their consequences for conformist decision-making - Fig 1 by Thomas J. H. Morgan (6265379)

“…(B) The probability that two observers who count individuals and instances, respectively, will disagree over which behaviour is in the majority is minimized when <i>r</i> = 1, but as <i>r</i> increases or decreases, the probability rapidly increases, slowing down as it reaches a maximum value of 1. …”

Image 2_PRP pre-treatment of the implantation zone improves the survival rate of fat autograft.jpeg by Ilona Pak (21074279)

Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria by Al-Sadeq, Duaa W.

“…In this study, we present the clinical and biochemical characterization of two novel CBS missense mutations that do not respond to pyridoxine treatment, namely c.689T > A (L230Q) and 215A > T (K72I), identified in a Chinese patient. …”
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Image_2_l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain.JPEG by Remon Soliman (10014386)

BRAF inhibition is associated with changes in BCL2 family member expression in tumors of patients with metastatic melanoma. by Dennie T. Frederick (591073)

“…<p>mRNA levels of <i>BIM</i>, <i>BCL2-XL</i>, <i>BCL2-W</i>, <i>BID</i> increased in patients with metastatic melanoma undergoing treatment with a selective inhibitor of BRAF^V600E while mRNA levels of <i>MCL-1</i> decreased; <i>BCL2</i> levels did not change significantly across patients. …”

Induction of ER stress does not lead to a MG phenotype. by Vangelis Kondylis (229490)

“…<p>(A–B) S2 cells were treated with vehicle (0.1% DMSO), 10 µg/ml tunicamycin (TUN), 1 µM thapsigargin (THA) and 5 mM DTT for 24 h, fixed and processed for IF. …”

Glibenclamide and quinine differentially modulate the intercellular synchronization of glucose-induced Ca²⁺ oscillations. by Sabine Bavamian (148288)

Image_2_The Candidate Schizophrenia Risk Gene Tmem108 Regulates Glucose Metabolism Homeostasis.jpeg by Jianbo Yu (415571)

“…</p>Conclusions<p>Hyperglycemia occurs more often in SCZ patients than in control, implying that these two diseases share common biological mechanisms, here we demonstrate that the Tmem108 mutant may represent such a comorbid mechanism.…”

ACT-induced Ca²⁺ influx triggers the toxin uptake by the different target cells. by Kepa B. Uribe (229307)

“…<p>(<b>A</b>) Pre-incubation of the different cells with nifedipine (10 µM), which was previously shown to effectively block the ACT-induced Ca²⁺ influx <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0074248#pone.0074248-Martn1" target="_blank">[18]</a>, very importantly decreased the toxin uptake by either CHO-K1 cells, as CR3⁺CHO-K1 cells or by J774A.1 and CR3<b>⁻</b>J774A.1 cells, hence suggesting that Ca²⁺ influx induced by ACT is a common master denominator in the different endocytosis routes used by the different cells to take the toxin. …”

Image2_Honokiol Induces Ferroptosis by Upregulating HMOX1 in Acute Myeloid Leukemia Cells.pdf by Xingrong Lai (12526789)

Image_2_Immune Monitoring Assay for Extracorporeal Photopheresis Treatment Optimization After Heart Transplantation.pdf by Maja-Theresa Dieterlen (6254165)

“…</p>Results<p>All BDCA⁺ DC subsets (BDCA1⁺ DCs: p < 0.01, BDCA2⁺ DCs: p < 0.01, BDCA3⁺ DCs: p < 0.01, BDCA4⁺ DCs: p < 0.01) as well as total T_regs(p < 0.01) and CD39⁺ T_regs(p < 0.01) increased during ECP treatment, while CD62L⁺ T_regs decreased (p < 0.01). …”

Table_2_Immune Monitoring Assay for Extracorporeal Photopheresis Treatment Optimization After Heart Transplantation.docx by Maja-Theresa Dieterlen (6254165)

“…</p>Results<p>All BDCA⁺ DC subsets (BDCA1⁺ DCs: p < 0.01, BDCA2⁺ DCs: p < 0.01, BDCA3⁺ DCs: p < 0.01, BDCA4⁺ DCs: p < 0.01) as well as total T_regs(p < 0.01) and CD39⁺ T_regs(p < 0.01) increased during ECP treatment, while CD62L⁺ T_regs decreased (p < 0.01). …”

Image_2_Effect of Restricted Feeding on Metabolic Health and Sleep-Wake Rhythms in Aging Mice.TIF by Yong-Xia Xu (11400785)

“…However, the potential of RF to improve metabolic health and sleep quality in older adults who are known to show a tendency toward increased weight gain and decreased sleep is unknown. …”

Flow chart of study selection. by Xu Han (141301)

“…GCA (WMD = 0.83μmol/L, 95%CI = 0.06; 1.6) and TCA (WMD = 0.51μmol/L; 95%CI = 0.18; 0.85) were both increased in serum sample; TCDCA (WMD = 2.64mmol/L, 95%CI = 0.16; 5.12) was rising, however GCDCA (WMD = -13.82mmol/L, 95%CI = -21.86; -5.78) was falling in bile sample of GSD patients. …”

Strain-Dependent Differences in Bone Development, Myeloid Hyperplasia, Morbidity and Mortality in Ptpn2-Deficient Mice by Florian Wiede (166231)

“…At 14 days of age, bone development was delayed in <em>Ptpn2^−/−</em> (BALB/c) mice. This was associated with increased trabecular bone mass and decreased bone remodeling, a phenotype that was not evident in <em>Ptpn2^{ex2−/ex2−}</em> mice. …”

Tet2 and Tet3 function upstream of the Notch and Wnt pathways during RGC differentiation and morphogenesis. by Pawat Seritrakul (4445662)

“…(I-L) Wnt signaling was upregulated by exposing wild-type embryos from 24hpf to 72hpf with 2μM BIO, a GSK3β inhibitor. (I,J) BIO-treated wild-type embryos showed reduced lamination, (K) a decreased percentage of <i>isl2b</i>:GFP⁺ RGCs per retina, and (L) decreased optic nerve diameter relative to DMSO-treated controls, (p = 0.00236 and p<0.0001). …”

Serp-2 reduces plaque growth in Apolipoprotein E deficient (ApoE^−/−) mice. by Kasinath Viswanathan (132259)

“…<p>Hyperlipidemic ApoE^−/− mice were infused with a bolus of Serp-2, CrmA or control saline after carotid cuff compression injury. …”

Table_1_Modes of Selection in Tumors as Reflected by Two Mathematical Models and Site Frequency Spectra.XLSX by Monika K. Kurpas (13183437)

“…The tumor-based SFS are better reproduced by Model A, pointing out a possible selection pattern of HER2+ tumor evolution. …”