Inactivation of NatB destabilized Drk, which mediated activated EGFR-induced MAPK activation. by Zhentao Sheng (107495)

DataSheet1_Ground Demonstration of the Use of Limnospira indica for Air Revitalization in a Bioregenerative Life-Support System Setup: Effect of Non-Nitrified Urine–Derived Nitroge... by Neha Sachdeva (11247690)

“…We observed that while the system could meet the desired oxygen levels of 20.3% under the nitrate and urea regime, it could only reach a maximum O₂ level of 19.5% under the ammonium regime.…”

DataSheet1_Efficacy and safety of Abelmoschus manihot capsule combined with ACEI/ARB on diabetic kidney disease: a systematic review and meta analysis.ZIP by Ying Tan (346135)

“…According to the subgroup analyses, the combination of AM and ARB seems to be more effective in reducing UAER than the combination of ACEI, and the addition of AM may achieve a more significant clinical effect on decreasing Scr for DKD patients with 24h-UTP>2 g or Scr>110–133 μmol/L and >133 μmol/L. …”

FIGURE 6 from Genome-wide CRISPR Screen Reveals RAB10 as a Synthetic Lethal Gene in Colorectal and Pancreatic Cancers Carrying SMAD4 Loss by Hélène Erasimus (15410643)

“…<b>A,</b> RAB10 expression assessed with Western blot analysis in the HT29_C4, SW620_C4, DLD1_C5 and MIAPaCa-2_C17 clones expressing Cas9 and infected with sgRNA against RAB10 (sgRNA #13 and sgRNA #14) and control nontargeting sgRNA (sgRNA #NT). …”

Knockdown NAA20 did not affect Drk mRNA level and Knockdown E3 ubiquitin ligase Ubr1 did not restore Drk protein level in <i>psid</i> mutant clones. by Zhentao Sheng (107495)

ShakB RNAi driven in the GF alters transmission at its output synapses. by Adeline P. Pézier (2600692)

Z-stack through a mouse kidney in vivo, showing typical renal structures like glomeruli (g), proximal tubules (pt) and extraglomerular capillaries (arrows). by Ina Maria Schießl (288061)

“…Proximal tubules (pt) showed green autofluorescence. a, left column: Z-stack without adjusted laser power, which was set at 15% of 3.2 W for best imaging conditions of the kidney surface. …”

Comparison of uracil-DNA mediated BER in extracts from WT and WRN KD cells by Jeanine A. Harrigan (14466)

“…The dotted line represents the average decrease in LP BER as a function of WRN down-regulation.…”

Image_1_Innovative breakthroughs facilitated by single-cell multi-omics: manipulating natural killer cell functionality correlates with a novel subcategory of melanoma cells.tif by Zhijie Zhao (686645)

“…A total of 10137 melanoma cells were further grouped into seven subtypes, i.e., C0 Melanoma BIRC7, C1 Melanoma CDH19, C2 Melanoma EDNRB, C3 Melanoma BIRC5, C4 Melanoma CORO1A, C5 Melanoma MAGEA4, and C6 Melanoma GJB2. …”

Table_1_Innovative breakthroughs facilitated by single-cell multi-omics: manipulating natural killer cell functionality correlates with a novel subcategory of melanoma cells.docx by Zhijie Zhao (686645)

“…A total of 10137 melanoma cells were further grouped into seven subtypes, i.e., C0 Melanoma BIRC7, C1 Melanoma CDH19, C2 Melanoma EDNRB, C3 Melanoma BIRC5, C4 Melanoma CORO1A, C5 Melanoma MAGEA4, and C6 Melanoma GJB2. …”

Data_Sheet_1_Soil Aggregates as a Source of Dissolved Organic Carbon to Streams: An Experimental Study on the Effect of Solution Chemistry on Water Extractable Carbon.docx by Malayika M. Cincotta (7829054)

Synthesis and Structure of 3,3-Dimethylindoline Squaraine Rotaxanes by Tia S. Jarvis (4039019)

“…Here we describe two rotaxanes that encapsulate a 3,3-dimethylindoline squaraine inside a tetralactam with anthracene sidewalls. …”

The proliferation curve of A549, H460 and 293T cell lines after pargyline treatment and transfection of Flag-LSD1 or LSD1 siRNA. by Tangfeng Lv (327103)

“…<p>The series of curves represent cell proliferation at 0 h to 48 h after exposure to different concentrations of pargyline treatment and transfection with the different plasmids. (A) The LSD1 inhibitor, pargyline (from top to bottom: 1mM, 2mM, 3mM and 4mM), and LSD1 siRNA inhibited proliferation of the A549 cell line. …”

MiR-34a and miR-34c overexpression or PDGFR-α/β silencing increases the response of NSCLC cells to TRAIL-induced apoptosis. by Michela Garofalo (276614)

“…MiR-34a or miR-34c and not miR-34b forced expression decreases PDGFRβ expression levels and reduces the activation of the ERK1/2. …”

R code and data for the publication "Predators minimize energy costs, rather than maximize energy gains under warming: Evidence from a microcosm feeding experiment" by Matthew Meehan (9754787)

“…We conclude that selection of prey based on body size changes with temperature as a trade-off for predators to balance increased metabolic demands.  …”

Child-directed speech in noise (Smith et al., 2024) by Nicholas A. Smith (17458706)

“…</p><p dir="ltr"><b>Supplemental Material S5.</b> First formant (<i>F</i>₁) mean.…”

DataSheet1_Pharmacogenetic association of the NR1H3 promoter variant with antihypertensive response among patients with hypertension: A longitudinal study.docx by Yu Chen (29959)

“…Therefore, this study aims to identify the associations between variants and antihypertensive drug response.</p><p>Methods: A longitudinal study including 1837 hypertensive patients was conducted in Northern China and followed up for a median 2.24 years. …”

Table1_Anti-inflammatory and protective effects of Pimpinella candolleana on ulcerative colitis in rats: a comprehensive study of quality, chemical composition, and molecular mecha... by Xiaoqi Liu (45630)

“…Pimpinella candolleana also modulated the levels of IL-2 and IL-6 in UC rats, reduced the expression of pro-inflammatory cytokines such as IL-6, MAPK8, TNF-α, CHUK, and IKBKB mRNA, and decreased the expression of TNF, IKBKB, JUN, and CHUK proteins in the colon of UC rats, thereby reducing inflammation and alleviating UC symptoms.…”

CD11b⁺-cells from cKO mice affect cancer cells in a direction opposite to EDA-FN exposure in vitro. by Stephanie Rossnagl (553093)

“…<p>(A) For the isolation of CD11b⁺-cells, two methods were used: isolation with antibody-coated Dynabeads and flow cytometry-based sorting. …”

Hippocampal CA3 cell loss and downregulation of cell proliferation. by Sandra A. Acosta (106213)

“…Ki67, a cell proliferation marker, revealed a significant chronic TBI-related decrease in the SVZ of cell proliferation only in the ipsilateral side relative to contralateral side and sham control animals (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0053376#pone-0053376-g003" target="_blank">Figure 3B</a>). …”