Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity by Jinxin Che (791250)

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity by Jinxin Che (791250)

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity by Jinxin Che (791250)

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity by Jinxin Che (791250)

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity by Jinxin Che (791250)

Chemical Inhibition of eEF1A-1 Peptide Elongation Activity Decreases Palmitate-Induced Cell Death. by Alexandra M. Stoianov (759321)

G9a decreases Rhox5 expression. by Mayumi Sugimoto (151133)

Image_1_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif by Marzia Spagnardi (9330602)

“…When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previously, we observed differential gene expression between the two populations, suggesting that colon tumors from AA patients display a decreased antitumor immune response and an increased expression of genes encoding proteins involved in inflammatory processes, such as Interleukin-1β (IL-1β). …”

Acute exercise decreased plasma insulin and glucose. by Mirian A. Kurauti (3146271)

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Decrease in apoptosis in the ischemic myocardium. by Laura A. Scrimgeour (9367459)

“…<p>There is an increase seen in JNK, pBAD, and pBAD/BAD with a decrease in pBCL-2, pBCL-2/BCL-2, and Caspase 3. …”

G9a decreases Rhox5 expression. by Mayumi Sugimoto (151133)

Decrease of cell viability and alterations of cell membrane permeability by infection with rotavirus isolates. by Carlos A. Guerrero (1264551)