Gradual increase in the extent of γ-secretase saturation with its substrate leads to gradual changes from the biphasic to the standard dose-response curves. by Željko M. Svedružić (105215)

“…A gradual increase in cDNAwtC99 results in a gradual increase in the enzyme activity at the lowest DAPT concentrations, and a decrease in the extent of enzyme activation by DAPT (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0050759#pone-0050759-t002" target="_blank">Table 2</a>). …”

Actin flow regains velocity after passing confined TCR clusters. by Cheng-han Yu (244912)

“…The velocity decrease between region 1 and 2 confirms our previous result. …”

Edible coatings with avocado oil on the quality of ‘Tommy Atkins’ mangoes by Saúl Dussán Sarria (16562287)

“…The results indicated that the combined effect of 2.52% avocado oil coating and refrigerated storage at 15 °C ±2°C and 80% ±5% RH led to a decrease in water loss (by 20%) at the end of the storage period, delayed mango senescence, inhibited microbial growth (indicated by the absence of molds and Escherichia coli), and did not influence sensory attributes of the fruit. …”

Comparisons of Clinical and Radiographic Outcomes. by Shunzhi Yu (460154)

“…</p>▴<p>Decrease rate of ROM: P = 0.005 (2-level and 3-level groups); P = 0.000(2-level and 4-level groups); P = 0.000 (3-level and 4-level groups) by Nemenyi test.…”

Metabolite profile of benzoic acid biotransformation with hippuric acid as outcome. by Cindy Irwin (3373793)

“…Enzyme nomenclature (names accepted by the IUBMB): EC 1.4.1.2: glutamate dehydrogenase; EC 2.1.1.2: guanidinoacetate N-methyltransferase; EC 2.1.2.1: glycine hydroxymethyltransferase (alt.: serine hydroxymethyltransferase); EC 2.1.2.10: aminomethyltransferase (a glycine synthetase); EC 2.1.3.3: ornithine carbamoyltransferase; EC 2.1.4.1: glycine amidinotransferase; EC 2.3.1.1: amino-acid N-acetyltransferase; EC 2.3.1.71: glycine N-benzoyltransferase (a GLYAT); EC 2.7.3.2: creatine kinase; EC 3.5.3.1: arginase; EC 4.3.2.1: argininosuccinate lyase; EC 6.2.1.2: butyrate-CoA ligase (a medium-chain acyl-CoA ligase); EC 6.3.4.5: argininosuccinate synthase; EC 6.3.5.5: carbamoyl-phosphate synthase (glutamine-hydrolyzing)</p>…”

The specificity of the funneling phenotype in <i>ptc</i> mutant embryos. by Krishna Moorthi Bhat (451722)

“…(B): Embryos were stained for the expression of Repo, a glial marker. A decrease in glial number is not evident in the mutant. …”

Loss of the capacity to induce IL-8 in <i>H. pylori</i> recovered from rhesus monkeys is associated with changes in the gene encoding CagY, an essential protein in the T4SS. by Roberto M. Barrozo (383765)

“…<p>(A–E) <i>H. pylori</i> was isolated from five rhesus macaques up to 14 months after experimental infection with <i>H. pylori</i> WT J166. …”

Actin dynamics within single dendritic spine under different conditions. by Jian-Hua Chen (373793)

“…At least this decrease is not nearly as significant as the increase observed in the less dynamic filament number, N₁ (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0128241#pone.0128241.g002" target="_blank">Fig 2F</a>, p = 0.0014), and the dynamics of the less dynamic filaments, τ₂ (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0128241#pone.0128241.g002" target="_blank">Fig 2D</a>, p = 0.0008), of those spines that exhibited significant growth after TEA. …”

The Merkel Cell Polyomavirus Minor Capsid Protein by Rachel M. Schowalter (121719)

“…Consistent with this observation, we show that VP3 is not detectable in MCV-infected cells, VP3 is not found in native MCV virions, and mutation of possible alternative VP3-initiating methionine codons did not significantly affect MCV infectivity in culture. In contrast, VP2 knockout resulted in a >100-fold decrease in native MCV infectivity, despite normal virion assembly, viral DNA packaging, and cell attachment. …”

Supplementary Material for: Dupilumab for chronic prurigo: case series on effectiveness, safety, and quality of life by Richter C. (4156546)

“…Results were reported up to two years after treatment with dupilumab. The response variables for DLQI, ItchyQoL, NRS and PAS analyses showed a statistically significant decrease over time (DLQI: (p = < 0.0001, [-0.84; -1.27]), ItchyQoL: (p = < 0.0001, [-9.89; -18.69], NRS maximum and average: p = < 0.0001, [-0.52; -0.86] and p = < 0.0001; [-0.55; -0.94] and PAS number of lesions: p = 0.0005; [-1.70; -5.28]). …”

Data_Sheet_1_Constant-Moderate and High-Intensity Interval Training Have Differential Benefits on Insulin Sensitive Tissues in High-Fat Fed Mice.PDF by Sergio F. Martinez-Huenchullan (6632717)

“…<p>In a mouse model of diet-induced obesity, this study determined if two exercise prescriptions with equivalent time and distance covered, [constant-moderate endurance (END) and high intensity interval training (HIIT)], exert differential metabolic benefits on insulin sensitive tissues. …”

Data_Sheet_1_Lifestyle Risk Factors and the Population Attributable Fractions for Overweight and Obesity in Chinese Students of Zhejiang Province.docx by Fang Gu (400554)

“…Based on the calculated PAFs, the predicted prevalence of overweight/obesity would decline moderately if lifestyle factors were modified, with the magnitudes of decrease vary by sex, age and residence. Generally, a larger reduction was estimated if the sleeping time was increased and TV time was reduced, with the prevalence of overweight/obesity decreased by 1.1% (95% CI: 0.7, 1.5%) and 0.9% (95% CI: 0.6, 1.2%), respectively.…”

Image_3_GPR37 Signaling Modulates Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Cells in Mice.JPEG by Hassan Saadi (5591228)

“…Signaling via GPR37 also perturbed OEC movement, resulting in a decrease in the olfactory bulb nerve layer in vivo. …”

Supplementary Material for: Dietary Protein and Fiber Affect Gut Microbiome and Treg/Th17 Commitment in Chronic Kidney Disease Mice by Serrano M. (4141276)

“…There was an 87% decrease in percentage of CD4+ Th17 + cells in spleen and an 85% decrease in peripheral blood, respectively, in LP-HF mice compared to the HP-LF mice. …”

Raw data for the forest soil properties. by Ananya Popradit (12520915)

“…<div><p>In a national park in Northeast Thailand, agricultural land has been converted from natural forest by small-scale farmers for cassava agriculture. …”

Raw data for the farmland soil properties. by Ananya Popradit (12520915)

“…<div><p>In a national park in Northeast Thailand, agricultural land has been converted from natural forest by small-scale farmers for cassava agriculture. …”

Image_1_GPR37 Signaling Modulates Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Cells in Mice.JPEG by Hassan Saadi (5591228)

“…Signaling via GPR37 also perturbed OEC movement, resulting in a decrease in the olfactory bulb nerve layer in vivo. …”

Changes in osteoblast differentiation and function of 4 week-old <i>Lmna</i>^−/− mice. by Wei Li (7081)

“…(<b>C</b>) Sections of plastic embedded proximal tibiae (secondary spongiosa) from <i>Lmna</i>^−/− mice and WT controls (n = 10 per group) were stained sequentially with toluidine blue (upper panels, Magnification ×40) for osteoblasts (black arrows) and osteocytes (red arrows) and ALP (lower panels, Magnification ×20) for osteoblasts (arrows). (<b>D</b>) A significant decrease (−47%) in the number of ALP expressing osteoblasts (N.Ob) and a significant decrease in osteocyte number (N.Ot) (−50%) were seen in <i>Lmna</i>^−/− mice compared with WT^+/+ mice. …”

Colonic Inflammation in Mice Is Improved by Cigarette Smoke through iNKT Cells Recruitment by Muriel Montbarbon (407341)

“…Using the InExpose® System, a smoking device accurately reproducing human smoking habit, we pre-exposed C57BL/6 mice for 2 weeks to CS, and then we induced colitis by administration of dextran sodium sulfate (DSS). …”

DataSheet1_Peptide Based Inhibitors of Protein Binding to the Mitogen-Activated Protein Kinase Docking Groove.docx by Anita Alexa (11057919)

“…These new constructs bound better to ERK2 and p38 kinases than the original peptide and they showed markedly increased cellular uptake. …”