Heat inactivation curves for the WT SULT1A1 protein and the 5C2, 5F8 and D249G SULT1A1 mutants. by Ilana Berger (198531)

“…The decrease in stability of the 5F8 mutant, relative to 1E8, and the D249G mutant, relative to the WT protein, highlight the trade-off between thermostability and the acquisition of new catalytic properties (see text for details).…”

CD43^-/- septic mice exhibit decreased frequencies of apoptotic CD4⁺ and CD8⁺ naïve T cells as compared to WT septic mice. by Katherine T. Fay (2576998)

“…D) CD43^-/- mice exhibited a decreased frequency of apoptotic naïve CD4⁺ T cells, defined as 7-AAD⁺ Annexin V⁺ CD44^LO CD62L^HI CD8⁺ cells, compared to WT mice after sepsis induction (7.2±1.1 vs 14.8±2.2, p = 0.02). …”

Comparison of the histopathological changes after KA/E2 treatment in WT and TLR2 KO mice. by Mi-Kyung Park (56053)

Mice with a decrease in α7 expression show no behavioral preference to a conditioned odor. by Jennifer L. Hellier (326477)

ENaC activity is decreased in oocytes expressing wild type S protein. by Germán Ricardo Magaña-Ávila (18446799)

DICER protein expression is significantly decreased in the absence of MOV10 and FMRP. by Monica C. Lannom (11772729)

Loss of <i>SLC4A11</i> expression and CHED-associated <i>SLC4A11</i> mutations in hCEnC lead to decreased cell viability during tBH-induced oxidative stress. by Doug D. Chung (3611387)

Heterozygous TIN2-R282H mutation decreases the frequency of telomere extension by telomerase. by Amanda K. Frank (778017)

CHAPb Tg mice show decrease cardiac performance. by Willemijn van Eldik (4662955)

Phosphosite mutations in Hcm1 decrease fitness in stress. by Michelle M. Conti (13514386)

Klf5 deficiency in mouse VSMCs leads to mitochondrial fission. by Dong Ma (584680)

Subjects:

Comparison of the Th2 cytokine expression level after treatment with KA/E2 in WT and TLR2 KO mice. by Mi-Kyung Park (56053)

eIF5a interacts with Mfn1 and preserves mitochondrial integrity. by Dong Ma (584680)

Subjects:

Klf5 deficiency leads to mitochondrial dyfunction in VSMCs. by Dong Ma (584680)

Subjects:

The correlation of the mitochondrial dynamics–related genes with Klf5 in mouse VSMCs. by Dong Ma (584680)

Subjects:

Bone mass and formation are decreased in Akt1-/- mice. by Naohiro Kawamura (33999)

Decreased Notch signaling in the retinoid-deficient spinal cord. by Marie Paschaki (179823)

Paxillin expression is decreased in CD45 KO BMDM. by Joëlle St-Pierre (439950)

“…Paxillin levels were decreased in both immunoprecipitates and total lysates of CD45 KO BMDM compared to WT. …”

PARP inhibition causes a decrease in Alt-EJ that is enhanced by Ku70 loss. by Sean M. Howard (687174)

“…Also shown is the cell cycle profile of siCTRL treated U2OS cells incubated with 5μM Olaparib (Olap), or mock treated (UN) prior to BrdU labeling and PI staining as in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004943#pgen.1004943.g002" target="_blank">Fig. 2C</a>. …”

Loss of ALS2 results in decreased levels of the lysosome-dependent degradation of LC3 in fibroblasts. by Shinji Hadano (251529)

“…It is notable that a 6 hr of starvation leads to decreased levels of the LC3- and p62-immunoreactive signals in WT cells, but not in <i>Als2</i>^−/− cells. …”