Stability parameters for SpGrx3 WT and mutants. by Trang Van Tran (16913946)

“…The R47F mutant, which formed dimers and exhibited the highest β-strand content, showed increased conformational flexibility and a significant decrease in catalytic rate due to the disturbance of β1-α2 interactions. …”

Kinetic parameters of SpGrx3 WT and mutants. by Trang Van Tran (16913946)

“…The R47F mutant, which formed dimers and exhibited the highest β-strand content, showed increased conformational flexibility and a significant decrease in catalytic rate due to the disturbance of β1-α2 interactions. …”

Impact of MK2-deficiency on adipose tissue inflammation. by Jan Freark de Boer (631340)

M^pro confers a significant reduction in growth in yeast caused by decreases in a variety of cellular proteins. by Jin Ou (16914305)

Kinetic and equilibrium constants for binding of WT and mutant FVIII-C2 proteins to BO2C11. by Jasper C. Lin (685807)

“…^†These substitutions resulted in a k_d >4X that of WT-FVIII-C2 for BO2C11 or abrogated binding to BO2C11. …”

RNF5 loss decreases ERK and Akt activation, CDK1 and Smo expression and KSHV lytic replication in PEL cells. by Xiaojuan Li (351842)

Serotonin deficiency decreases calcium transporters expression in the mammary gland on d 10 of lactation. by Jimena Laporta (383836)

Lack of PD-L1 expression by host tissues increases numbers of activated donor T cells but decreases donor Tregs in spleen. by Mohammad S. Hossain (415643)

AMPK phosphorylation and AC5 and AC6 gene expression in hearts from WT and AMPKα2-/- mice following TAC. by Anne Garnier (130125)

Subjects:

The recruitment of MYD88 to TLR2 and IRAK-4 phosphorylation are decreased in β3-integrin–silenced cells. by Tatiana Gianni (499634)

Three variants lower the rheobase and increase firing frequency of Ca_V3.3, while the A398V variant shows the opposite effect. by Yousra El Ghaleb (22075892)

Subjects:

Treatment with rVP1 decreases NF-κB activation that modulates CCL2 production. by Tai-An Chen (211390)

Su(H) and RBPJ AOS variants decrease DNA binding. by Ellen K. Gagliani (11478756)

Increased accumulation of mutant huntingtin aggregates and decreased mobility of autophagosomes in the axon of AP-4 ε KO hippocampal neurons. by Raffaella De Pace (5147120)

HIV-1 CA mutations selected during passage in rhTRIM5α-expressing cells decrease sensitivity to rhTRIM5α. by Steven J. Soll (270043)

Western blot analysis of LET-60 levels in WT and <i>let-60</i> mutants. by Maximilian Kramer-Drauberg (8981141)

Western blot analysis of MPK-1 levels in WT and <i>let-60</i> mutants. by Maximilian Kramer-Drauberg (8981141)

Increased ROS level decreases RLS in respiratory-deficient cells. by Dae-Gwan Yi (5410298)

HO-1 overexpression decreases Nox4 activity in C-20/A4 chondrocytes. by Francis Rousset (424375)

Decreased proliferation, but not apoptosis, is responsible for reduction of growth plate height. by Marco Cardelli (494637)