DataSheet1_Vitamin D Deficiency Impacts Exposure and Response of Pravastatin in Male Rats by Altering Hepatic OATPs.docx by Jinfu Peng (11087103)

“…VD deficiency decreased the Oatp1a1 and Oatp2b1 expression in the liver, but not in the small intestine. …”

DataSheet1_Paeoniae Radix Rubra can enhance fatty acid β-oxidation and alleviate gut microbiota disorder in α-naphthyl isothiocyanate induced cholestatic model rats.docx by Jing-Jing Xu (769628)

“…Pathway analysis revealed that PRR significantly alleviated eight pathways (β-alanine metabolism). Furthermore, we found that PRR significantly reversed the decrease of Cpt1a, Hadha, Ppara, and Slc25a20 (four genes relevant to fatty acid β-oxidation) mRNAs caused by ANIT, and PRR conspicuously decreased nine acylcarnitines (the forms of fatty acids into mitochondria for β-oxidation) that increased in model rats. …”

DataSheet1_Methylmercury content in soil and litter from the Amazonian rainforest and its potential fate during forest fires.PDF by Anne Helene Fostier (12654831)

“…Hence, the aim of this work was to determine the total mercury [THg] and methylmercury [MeHg] concentrations in litter and surface soil, MeHg deposition via litterfall, and the MeHg fate during a forest fire in the Amazonian rainforest. Sampling of litter, soil (0–1, 1–2, and 2–5 cm), and ash was carried out before (BB) and after (AB) a prescribed forest fire. …”

DataSheet1_Methylmercury content in soil and litter from the Amazonian rainforest and its potential fate during forest fires.PDF by Anne Helene Fostier (12654831)

“…Hence, the aim of this work was to determine the total mercury [THg] and methylmercury [MeHg] concentrations in litter and surface soil, MeHg deposition via litterfall, and the MeHg fate during a forest fire in the Amazonian rainforest. Sampling of litter, soil (0–1, 1–2, and 2–5 cm), and ash was carried out before (BB) and after (AB) a prescribed forest fire. …”

Repression of <i>hmsT</i> by Fur. by Fengjun Sun (113206)

“…</b> The radioactively labeled promoter-proximal DNA fragment of <i>hmsT</i> was incubated with increasing amounts of purified His-Fur protein, and then subjected to 4% (w/v) polyacrylamide gel electrophoresis; with the increasing amounts of His-Fur, the band of free target DNA disappeared, and a retarded DNA band with decreased mobility turned up, which presumably represented the protein-DNA complex. …”

Response of plant communities to herbivory. by Arjun B. Potter (6445646)

“…<p>On average, the presence of large mammalian herbivores led to an increase (as shown by the log-response ratio of control-exclosure comparisons, <i>y</i>-axis) in plant-community richness, a decrease in evenness, and a decrease in biomass per quadrat relative to exclosures by the end of the growing season. …”

Transient inhibition of excitatory synaptic inputs in granule cell after TBI. by Xiang Gao (4077)

“…The traces in A2 were averaged from 150–260 events. (B), summary data showing the decrease of mEPSCs frequency, but not amplitude, rising time, and decay time constant. *, <i>P</i><0.01.…”

RKIP is required to inhibit STAT3 activation and breast tumor xenograft growth. by Saad Yousuf (541082)

“…Tumors were measured using calipers twice weekly, and volumes were calculated using the formula: weight (mg)  =  [width (mm)² × length (mm)]/2. A paired t-test was performed indicating the decrease of RKIP *(p<0.002) or increase of **(p<0.008) si175RKIP, ***(p<0.002) STAT3 of tumor growth when compared to EV. …”

Reduced ERG amplitudes in NaIO₃-treated αB crystallin knockout (αB-/-) mice. by Peng Zhou (116747)

“…<p>Three weeks after tail vein injection of 20/kg body weight NaIO₃, mesopic ERG responses were recorded in PBS-treated WT, NaIO₃-treated WT, PBS-treated αB-/-, and NaIO₃-treated αB-/- mice (representative ERGs shown in A). …”

The effects of Nodal on proliferation and apoptosis are dependent on activation of the type 1 receptor (ALK4/7). by Daniela F. Quail (123286)

“…<p>(A) Western blot analysis demonstrating that phosphorylation of SMAD2 decreases with SB431542 treatment (1–10 µM) in MDA-MB-231 cells. …”

Trends in China’s anthropogenic emissions since 2010 as the consequence of clean air actions by Bo Zheng (5701343)

“…The emission reduction rates markedly accelerated after the year 2013, confirming the effectiveness of China’s Clean Air Action that was implemented in 2013. We estimated that during 2013–2017, China’s anthropogenic emissions decreased by 59% for SO2, 21% for NOx, 23% for CO, 36% for PM10, 33% for PM2.5, 28% for BC, and 32% for OC. …”

Conceptual summary of <i>in vitro</i> findings. by Jason Y. Park (591767)

“…<p>(A) In patients with Th2-cytokine driven esophageal eosinophilia who have little or no reflux, epithelial cell expression of eotaxin-3 will be high in both the proximal and distal esophagus. …”

Social hierarchy modulates responses of fish exposed to contaminants of emerging concern by Jelena Ivanova (4524880)

“…Furthermore, we confirmed our predictions that exposure to estrogenic CECs would homogenize plasma vitellogenin response (E1: cluster mean SSC values decreased to 4.33 and 4.86 relative to those of control; E2: decreased to 4.8 and 5.37) across the social hierarchy. …”

Effect of oviposition by Bactrocera dorsalis on the antioxidant activity of orange juice by M. Ni (7530485)

“…Furthermore, the free-radical scavenging activity decreased from 22.297% to 5.393%. Correlation analysis indicated significant correlations between Vc concentration, total phenol content, and antioxidant activity of orange juice after B. dorsalis infestation. …”

Table_3_Disorganized Gut Microbiome Contributed to Liver Cirrhosis Progression: A Meta-Omics-Based Study.XLS by Li Shao (151875)

“…Inspired from intestinal disorders in LC patients, we investigated the associations between gut microbiome and disease progression based on a raw metagenomic dataset of 47 healthy controls, 49 compensated, and 46 decompensated LC patients from our previous study, and a metabolomic dataset of urine samples from the same controls/patients using ultra-performance liquid chromatography/mass spectrophotometry system. …”

A New Murine Model for Gastrointestinal Anthrax Infection by Tao Xie (146080)

“…<div><p>The scientific community has been restricted by the lack of a practical and informative animal model of gastrointestinal infection with vegetative <i>Bacillus anthracis</i>. We herein report the development of a murine model of gastrointestinal anthrax infection by gavage of vegetative Sterne strain of <i>Bacillus anthracis</i> into the complement-deficient A/J mouse strain. …”

Supplementary Material for: Effect of benralizumab on mucus plugs in severe eosinophilic asthma by Sakai N. (4124452)

“…In this study, we examined the efficacy of benralizumab on mucus plugs using computed tomography (CT) imaging. …”

Blink-induced error and microsaccade properties. by Francisco M. Costela (647619)

“…Shaded area indicates the SEM across monkeys (<i>n</i> = 5 monkeys).</p>…”

Nucleosomes Containing Methylated DNA Stabilize DNA Methyltransferases 3A/3B and Ensure Faithful Epigenetic Inheritance by Shikhar Sharma (230953)

“…<div><p>How epigenetic information is propagated during somatic cell divisions is still unclear but is absolutely critical for preserving gene expression patterns and cellular identity. Here we show an unanticipated mechanism for inheritance of DNA methylation patterns where the epigenetic mark not only recruits the catalyzing enzyme but also regulates the protein level, i.e. the enzymatic product (5-methylcytosine) determines the level of the methylase, thus forming a novel homeostatic inheritance system. …”

A Bayesian Nonlinear Mixed-Effects Regression Model for the Characterization of Early Bactericidal Activity of Tuberculosis Drugs by Divan Aristo Burger (645493)