Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 by Austin, Carter

“…In the same period, PUV increased in central Europe, eastern Europe, and central Asia by 116·1% (8·0–218·2). Our forecasts predict a continued global decline in HIV incidence and mortality, with the number of people living with HIV peaking at 44·4 million (40·7–49·8) by 2039, followed by a gradual decrease. …”
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Association between central obesity indices and iron status indicators among Qatari adults by Kerkadi, Abdelhamid

“…Of the participants with a large waist circumference, 31.7% had anaemia. …”
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Why Construction Projects are delayed in PWA: Problems and Solutions by Al Marri, Dana Ahmad

“…The solution consists of two parts, (1) identify the relevant corrective, immediate and preventive actions, and (2) develop a responsibility matrix for the implementation of those solutions to ensure its governance.…”
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Gender Prespecified Sampling for Cost Control by Trung Le1, Kien

“…The benefits are twofold: (1) a reduction in survey costs and (2) simplified withinhousehold selection. …”
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Impact of composition and salinity on swelling and gel strength of poly (acrylamide-co-acrylic acid) preformed particle gel by Ben Ali, Ahmed

“…The highest equilibrium swelling capacity among the six preformed particle gel samples was obtained for PPG2, which has the highest acrylic acid amount and the lowest crosslinker content, with a swelling ratio of 2400 g/g in deionized water and 59.8 g/g in brine 1 (67535.8 mg/l). …”
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Evaluation of the inhibition performance of piperazine-based polyurea towards mild steel corrosion: The role of keto-enol tautomerization by Abdulazeez, Ismail

“…The presence of PUCorr at 100 ppm decreases the corrosion current density from 30.3 to 3.05 μA/cm2 in 0.5 M NaCl at room temperature, exhibiting a remarkable inhibition efficiency of 94.5%. …”
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Self-healing performance of smart coatings modified with different corrosion inhibitors. by Habib, Sehrish

“…The present work aimed to explore the purpose of CeO2 as a carrier for corrosion inhibitors and its capability to release inhibitors, to achieve decent corrosion protection efficiency in epoxy-based polymeric nanocomposite coatings. …”
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Emerging clay-aryl-gold nanohybrids for efficient electrocatalytic proton reduction by Jlassi, Khouloud

“…Both nanohybrids showed efficient electrochemical activity for HER in acidic condition (0.1 M H2SO4) with high current density up to −25 mA.cm−2 at −1 V and 0.148 mV onset. …”
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Functionalization of reverse osmosis membrane with graphene oxide to reduce both membrane scaling and biofouling by Ashfaq M.Y.

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Propylene oxide assisted sol-gel synthesis of zinc ferrite nanoparticles for solar fuel production by Bhosale, Rahul R.

“…For the synthesis of Zn-ferrite, metal precursors (ZnCl2 and FeCl2·4H2O) were first dissolved in ethanol, and then PO was added dropwise for the gel formation. …”
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Chronic melatonin treatment improves obesity by inducing uncoupling of skeletal muscle SERCA-SLN mediated by CaMKII/AMPK/PGC1α pathway and mitochondrial biogenesis in female and ma... by Salagre, D.

“…The identification of VL skeletal muscle-based NST by uncoupling of sarcoendoplasmic reticulum Ca2+-ATPase (SERCA)- sarcolipin (SLN) prompted us to investigate whether melatonin is a SERCA-SLN calcium futile cycle uncoupling and mitochondrial biogenesis enhancer. …”
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Prospects of Biocrude Production Potential from Local Diatom by Al-Namimi, Sara Mohammed

“…After 7 days of growth, the final biomass density reached 0.52 g/L, and average biomass productivity was 6.7 g/m2/d. Next, Nitzchia reversa was harvested using a 25 m2 crossflow filtration membrane module. …”
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Estimation of Mechanical Properties of Copper Powder Filled Linear Low-Density Polyethylene Composites by Singh, S.

“…The ANN approach runs the threshold TANSIG-PURELIN function for 200 epochs with a back propagation algorithm. The input parameters manipulated for the prediction were elongation at break (δ), stress at break (ρ), Young’s modulus (Y), volume fraction of the filler (ϕ) and constants (KE1,KE2,KS1,KS2,KS3,KS4,KY1). …”
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Quality, safety and efficiency in practice: Risk assessment and standardisation of anesthesia equipment and supplies in operating theaters of high-volume tertiary-care academic med... by Hammad Y.

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Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update by Smatti, Maria K.

“…Among all the EBV genes, most of the recent investigations focused on studying the LMP-1 oncogene because of its high degree of polymorphism and association with tumorigenic activity. There are two main EBV genotypes, Type 1 and 2, distinguished by the differences in the EBNA-2 gene. …”
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Resilience-robustness improvement by adaptable operating pattern for electric vehicles in complementary solar-vehicle management by Mehrjerdi, Hasan

“…The model also restores 51.5% of the critical loads under two concurrent events. The model is highly sensitive to the critical loads and reducing them by 10% decreases the loss of energy by about 15%. 2021 Elsevier Ltd…”
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Allelopathic Effects of the Invasive Prosopis juliflora (Sw.) DC. on Native Plants: Perspectives toward Agrosystems by Bibi, Shazia

“…The seed germination and radicle length of S. aegyptica and H. perfoliata were significantly decreased at 2 mg mL−1 of extract of P. juliflora. …”
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Visible Light Photocatalytic Activity of Ag/WO3 Nanoparticles and its Antibacterial Activity Under Ambient Light and in The Dark by Maha, Matalkeh

“…Ultraviolet–visible spectra analysis observed a large redshift in the absorbing band edge and decreased bandgap energy from 2.6 to 2.1 eV. …”
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Perinatal outcomes following Helping Babies Breathe training and regular peer-peer skills practice among village midwives in Sudan. by Arabi, Ame

“…Excluding 11 macerated fetuses, there were 55 perinatal deaths: 14 FSB/18 ENND (6 months pre-HBBT(+RPPSP)) and 10 FSB/13 ENND (18 months post-HBBT(+RPPSP)). FSB rates decreased from 10.5 to 3.3 per 1000 births ((χ(2))=8.6209, p=0.003), while ENND rates decreased from 13.5 to 4.3 per 1000 live births ((χ(2))=10.9369, p=0.001) pre-HBBT(+RPPSP) and post-HBBT(+RPPSP), respectively. …”
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