Gramine Derivatives Targeting Ca²⁺ Channels and Ser/Thr Phosphatases: A New Dual Strategy for the Treatment of Neurodegenerative Diseases by Rocío Lajarín-Cuesta (1530580)

“…Hence, we propose this multitarget approach as a new and promising strategy for the treatment of neurodegenerative diseases.…”

Electrical stimulation induces increased glucose uptake and decreased glycogen content in C2C12 myotubes. by Yasuko Manabe (107491)

Knockdown of ERK2, but not ERK1, decreases LPS-induced DNase I accessibility of the G-CSF promoter. by Shwu-Fen Chang (761846)

Decrease in I_Na caused by I_leak versus the NEP. by Lisha Yang (1695241)

Lung cancer cell lines secrete BMP2 and knockdown of BMP2 decreases BMP signaling and induces cell death. by Elaine Langenfeld (402034)

“…(<b>D</b>) Western blot analysis of H1299 cells in SFM 48 hours after being transfected with control siRNA or siRNA targeting BMP2. BMP2 knockdown causes a decrease in expression of pSmad 1/5 and Id1. …”

TNFAIP9 expression was increased in mice with chronic kidney disease (CKD) induced by 5/6 nephrectomy (Nx). by Ying Chen (9697)

Subjects:

Combination of cAMP-enhancing and cAMP-inhibiting neuromodulation can increase or decrease the AP threshold throughout the apical dendrite in the Hay-model L5PC. by Tuomo Mäki-Marttunen (388882)

Decreased expression of proteins involved in mitochondrial dynamics and regulation of oxidative stress in prion infected mice. by Anne Ward (334296)

Expression of MHC II decreased in old Gas7-deficient soleus while MHC I expression increased. by Bo-Tsang Huang (162584)

Changes in neural activity were decreased in animals pre-exposed to 5-HT and <i>mod-1</i> mutants when the worms switched their locomotive direction. by Haruka Mori (8082215)

“…<p>(A–F) the neural activity of the RID changes during the transition periods from backward to forward locomotion (A–C) and from forward to backward locomotion (D–F) in the mock (A: p = 1.5 × 10⁻⁵; D: p = 5.5 × 10⁻¹³), 5-HT exposed (B: p = 0.092; E: p = 0.79), and <i>mod-1</i> mutant (C: p = 0.081; F: p = 0.93) groups. …”

E2-induced PKCδ activation is responsible for the ASL height decrease in CuFi-1 cells. by Vinciane Saint-Criq (479729)

<i>Ext1</i> mutant lungs exhibit a decrease in SHH-FGF10 signaling. by Hua He (120374)

“…The expression of <i>Fgf10</i>, <i>Etv4</i>, <i>Spry2</i>, <i>Dusp6</i> and <i>Bmp4</i> were increased, while the expression of <i>Etv5</i> was decreased in <i>Ext1</i>^<i>f/f</i><i>; Shh</i>^<i>cre</i> mutant lungs compared to control lungs. …”

Intrathecal injection of mycolactone triggers a decrease of pro-inflammatory cytokines in spinal cord of Sham rats. by Caroline Isaac (4600654)

B-factor values of Ca_V3.3 M1425 substitutions. by Yousra El Ghaleb (22075892)

Subjects:

METH decreased basal pERK1/2 levels and potentiated ERK1/2 phosphorylation induced by 6-OHDA. by Amina El Ayadi (341955)

“…METH decreased activation of ERK 1/2 in a concentration-dependent manner (0, 0.5, and 1 mM at the 24 hr time point) and enhanced the activation of ERK1/2 after 6-OHDA exposure. …”

(A-C) Force versus drill depth and torque versus drill depth. by Marsel Ganeyev (21453399)

Image2_Immunization of Broiler Chickens With a Killed Chitosan Nanoparticle Salmonella Vaccine Decreases Salmonella Enterica Serovar Enteritidis Load.pdf by Keila Acevedo-Villanueva (10531191)

“…Chitosan nanoparticle (CNP) vaccines can be used to deliver Salmonella antigens orally. We investigated the efficacy of a killed Salmonella CNP vaccine on broilers. …”

Sex differences in baseline characteristics. by Kirsten Grossmann (10704657)

Subjects:

Stimulation of Caco-2 cells with IFN-γ decreases claudin-4 expression. by Manigandan Lejeune (458492)

dsRNA-induced decrease in Mcl-1 protein expression depends on eIF2α phosphorylation by PKR. by Maikel L. Colli (179059)