Transthyretin Amyloidosis: Chaperone Concentration Changes and Increased Proteolysis in the Pathway to Disease by Gonçalo da Costa (198731)

“…Since non-mutated transthyretin also forms amyloid in systemic senile amyloidosis and some mutation bearers are asymptomatic throughout their lives, non-genetic factors must also be involved in transthyretin amyloidosis. We discovered, using a differential proteomics approach, that extracellular chaperones such as fibrinogen, clusterin, haptoglobin, alpha-1-anti-trypsin and 2-macroglobulin are overrepresented in transthyretin amyloidosis. …”

A New Highly Sensitive Method to Assess Respiration Rates and Kinetics of Natural Planktonic Communities by Use of the Switchable Trace Oxygen Sensor and Reduced Oxygen Concentrati... by Laura Tiano (524349)

“…Here we present the assessment of a new highly sensitive method, that combine Switchable Trace Oxygen (STOX) sensors and all-glass bottle incubations, where the O₂ concentration was artificially lowered. …”

The decrease in lactate induced by pyruvate is blocked by inhibition of MAS and of the TCA cycle in HKI/HKII double KD cells. by Scott John (228011)

“…Again, upon addition of 2mM pyruvate there is a rapid and sustained decrease in intracellular lactate level (phase 2). …”

Supplementary Material for: Decrease of Hyperintense Vessels on Fluid-Attenuated Inversion Recovery Predicts Good Outcome in t-PA Patients by Sakuta K. (4147642)

“…HV scores (range 1-7) were evaluated according to Alberta Stroke Program Early Computed Tomography Score territories, and then by subtracting HV scores at 1 h after t-PA infusion from those on admission, with a result of >1 defined as decrease in HV score (DHV). …”

DataSheet2_Decreasing incidence and mortality of lung cancer in Hungary between 2011 and 2021 revealed by robust estimates reconciling multiple data sources.xlsx by Gabriella Gálffy (177759)

“…Up until the COVID-19 pandemic, lung cancer incidence was decreasing by 3.18% (2.1%–4.3%) yearly in men, while there was no significant decrease in women. …”

Image_2_A Shift in Myeloid Cell Phenotype via Down Regulation of Siglec-1 in Island Macrophages of Bone Marrow Is Associated With Decreased Late Erythroblasts Seen in Anemia of Critical Illness.tiff by Shirin Hasan (7894118)

“…There were more (2.5-fold) EEBs and less LEBs (2.4-fold) per million TBM cells in B; with a corresponding decrease in Siglec-1 and Ly6G expressions in EBIMØ associated with EEB. …”

Colistin-phage combinations decrease antibiotic resistance in <i>Acinetobacter baumannii</i> via changes in envelope architecture by Xiaoqing Wang (514179)

Table_1_The Increase in Paraoxonase 1 Is Associated With Decrease in Left Ventricular Volume in Kidney Transplant Recipients.docx by Philip W. Connelly (10522333)

“…We previously reported that the decrease in NT-proB-type natriuretic peptide (NT-proBNP) was associated with a decrease in adiponectin. …”

Letrozole treatment resulted in a decrease in Bacteroidales and increase in Clostridiales. by Scott T. Kelley (158464)

Nef Decreases HIV-1 Sensitivity to Neutralizing Antibodies that Target the Membrane-proximal External Region of TMgp41 by Rachel P.J. Lai (193116)

“…Indeed, Nef and Glycosylated-Gag decreased the efficiency of virion capture by 2F5 and 4E10, but not by other nAbs. …”

Macroalgae Decrease Growth and Alter Microbial Community Structure of the Reef-Building Coral, <em>Porites astreoides</em> by Rebecca Vega Thurber (41633)

“…To determine if macroalgae alter the coral microbiome, we conducted a field-based experiment in which the coral <em>Porites astreoides</em> was placed in competition with five species of macroalgae. …”

Activated γδ T cells, but not αβ T cells, express decreased levels of CD73. by Dongchun Liang (636452)

Decreased miR-29b/c in GC tissue samples. by He Cui (229445)

Depletion of TbSWR1 caused a decrease of reporter luciferase activity within a PTU. by Tim Vellmer (12837414)

Subjects:

Decrease of citric acid produced by <i>Aspergillus niger</i> through disruption of the gene encoding a putative mitochondrial citrate-oxoglutarate shuttle protein by Kohtaro Kirimura (414508)

Interactions between αv-Integrin and HER2 and Their Role in the Invasive Phenotype of Breast Cancer Cells In Vitro and in Rat Brain by Sangeet Lal (776570)

“…<div><p>Background</p><p>We tested the hypothesis that αv-integrin and the human epidermal growth factor receptor type 2 (HER2) interact with each other in brain trophic metastatic breast cancer cells and influence their invasive phenotype.…”

A Diverse Family of Host-Defense Peptides (Piscidins) Exhibit Specialized Anti-Bacterial and Anti-Protozoal Activities in Fishes by Scott A. Salger (3072093)

“…The Class I piscidins (22 amino acids in length; striped bass and white bass piscidin 1 and piscidin 3) show broad-spectrum activity against bacteria and ciliated protozoans, while the Class III piscidins (55 amino acids in length; striped bass and white bass piscidin 6 and striped bass piscidin 7) primarily show anti-protozoal activity. The Class II piscidins (44–46 amino acids in length; striped bass and white bass piscidin 4 and white bass piscidin 5) have a level of activity against bacteria and protozoans intermediate to Classes I and III. …”

Decreasing ShcA expression enhances TGF-β-induced Smad signaling. by Baby Periyanayaki Muthusamy (838234)

“…<p>(A) Smad3 and Smad2 activation, assessed by pSmad3 or pSmad2 immunoblotting, in NMuMG cells, transfected with control or ShcA siRNA (siShc-a), in the absence of added TGF-β or in response to 2 ng/ml TGF-β for 30 min. …”

Decreased antihyperglycemic drug use driven by high out-of-pocket costs despite Medicare coverage gap closure by Mugdha Gokhale (8676201)

“…<a><b>Objectives</b></a>: <a>Using the 2016 Medicare part D coverage gap as an example, we explored effects of increased out-of-pocket costs on adherence to branded </a>dipeptidyl peptidase-4 inhibitors (DPP-4i) in patients without financial subsidies, relative to subsidized patients who do not experience increased spending during the gap. …”

Image_1_Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells.tif by Kanako Iwasaki (16451151)

“…</p>Methods<p>In this study, we explored the direct role of IGF1R in β-cell function and senescence using two independent mouse models with decreased IGF1/IGF1R signaling: a) Ames Dwarf mice (Dwarf ^+/+), which lack growth hormone and therefore have reduced circulating levels of IGF1, and b) inducible β-cell-specific IGF1R knockdown (βIgf1rKD) mice.…”