Decrease of neuronal FKBP4/FKBP52 modulates perinuclear lysosomal positioning and MAPT/Tau behavior during MAPT/Tau-induced proteotoxic stress by Béatrice Chambraud (3371201)

“…In this study, we demonstrate that FKBP4 decrease in a human neuronal cell line (SH-SY5Y) and in dorsal root ganglion (DRG) neurons from human MAPT^P301S transgenic mice affected the function of the autophagy-lysosomal system under MAPT induced proteotoxic stress conditions. …”

Persistent pseudohypoxia results in a gradual decrease of Ambra1 and Beclin 1 protein levels. by Somayeh Pourpirali (757274)

Do we treat our patients or rather periodontal microbes with adjunctive antibiotics in periodontal therapy? A 16S rDNA microbial community analysis by Daniel Hagenfeld (319909)

“…We found statistically noticeable decreased richness, and increased dissimilarity in the antibiotic, but not in the placebo group after therapy. …”

Suppression of endogenous human TRAM expression decreases R848 mediated <i>CCL5</i> and <i>IFN-β</i>, but not <i>TNF-α</i> expression. by Enda Shevlin (628477)

The decrease in c-Myc protein levels in A549 cells was primarily due to proteasomal degradation. by Qin Li (36669)

Pushing the Limits of Organometallic Redox Chemistry with an Isolable Mn(−I) Dianion by Ageliki Karagiannis (18991224)

“…Cyclic voltammograms show a Mn^0/–I redox couple at −3.13 V vs Fc^+/0 in tetrahydrofuran (THF), −3.06 V in 1,2-dimethoxyethane, and −2.85 V in acetonitrile. …”

Silencing of MAGE-A expression decreases the levels of MDM4 via the proteasome and increase MDM2/MDM4 association. by Lynnette Marcar (743770)

Decreased CCL2 levels protect A20^AEC-KO mice against influenza A infection by Jonathan Maelfait (181048)

Glucose infusion decreases AMPK Thr¹⁷² phosphorylation and α2 AMPK activity, and increases AMPK Ser^485/491 phosphorylation in red gastrocnemius muscle. by Kimberly A. Coughlan (743018)

<i>crh-1</i> mutants exhibit a decrease of <i>daf-7</i> expression in the ASI neurons. by JiSoo Park (11133976)

Therapeutic effect of TAS5315 on the decrease in bone strength in a mouse CIA model. by Daichi Akasaka (14670684)

Multiple Autoimmune-Associated Variants Confer Decreased IL-2R Signaling in CD4⁺CD25^hi T Cells of Type 1 Diabetic and Multiple Sclerosis Patients by Karen Cerosaletti (501670)

“…To examine this question we used phosphorylation of STAT5 (pSTAT5) as a downstream measure of IL-2R signaling, and found a decreased response to IL-2 in CD4⁺CD25^hi T cells of T1D and MS, but not SLE patients. …”

MVEC viability is decreased over time in PEG-based hydrogels. by Rebecca A. Scott (488956)

Alteration of Wnt5a expression and of the non-canonical Wnt/PCP and Wnt/PKC-Ca²⁺ pathways in human osteoarthritis osteoblasts by Xavier Martineau (4332922)

“…Human Ob isolated from sclerotic subchondral OA bone tissue show an altered phenotype, a decreased canonical Wnt/β-catenin signaling pathway (cWnt), and a reduced mineralization <i>in vitro</i>. …”

DataSheet_1_Circulating exosomes decrease in size and increase in number between birth and age 7: relations to fetal growth and liver fat.pdf by Marta Díaz (337207)

“…Circulating exosomes of SGAs (as compared to those of AGAs) had a larger size at birth [146.8 vs 137.8 nm, respectively; p=0.02], and were in lower number at ages 2 [4.3x10¹¹vs 5.6x10¹¹ particles/mL, respectively; p=0.01] and 7 [6.3x10¹¹vs 6.8x10¹¹ particles/mL, respectively; p=0.006]. …”

Sodium-Glucose Transporter-2 (SGLT2; SLC5A2) Enhances Cellular Uptake of Aminoglycosides by Meiyan Jiang (438439)

“…Yet, the ototoxic and nephrotoxic side-effects of these drugs remain serious complications. A major site of gentamicin uptake and toxicity resides within kidney proximal tubules that also heavily express electrogenic sodium-glucose transporter-2 (SGLT2; SLC5A2) <i>in vivo</i>. …”

Long Tree-Ring Chronologies Provide Evidence of Recent Tree Growth Decrease in a Central African Tropical Forest by Giovanna Battipaglia (711570)

Phase Behavior and Structural Characterization of Ionic Clathrate Hydrate Formed with Tetra‑<i>n</i>‑butylphosphonium Hydroxide: Discovery of Primitive Crystal Structure by Takayuki Kobori (1556734)

“…The highest ionic clathrate hydrate–solution equilibrium temperature was determined to be 290.2 K at a TBPOH mole fraction of 0.0340, which corresponds to the congruent composition. …”

DataSheet2_WNT5A Interacts With FZD5 and LRP5 to Regulate Proliferation and Self-Renewal of Endometrial Mesenchymal Stem-Like Cells.docx by Tianqi Li (1335987)

“…Among the various receptors that have been reported to interact with WNT5A, we found FZD5 abundantly expressed by eMSC when compared to unfractionated stromal cells. …”

DataSheet2_WNT5A Interacts With FZD5 and LRP5 to Regulate Proliferation and Self-Renewal of Endometrial Mesenchymal Stem-Like Cells.docx by Tianqi Li (1335987)

“…Among the various receptors that have been reported to interact with WNT5A, we found FZD5 abundantly expressed by eMSC when compared to unfractionated stromal cells. …”