Design, Synthesis, and Biological Evaluation of [1,2,5]Oxadiazolo[3,4‑<i>b</i>]pyridin-7-ol as Mitochondrial Uncouplers for the Treatment of Obesity and Metabolic Dysfunction-Assoc... by Mary A. Foutz (20361830)

“…Pharmacokinetic studies indicated a half-life of 2 h, <i>C</i>_max of 35 μM, and no observed adverse effects at 1,000 mg kg^–1 dose in mice. …”

The apparent Ca²⁺ affinity of release is decreased by hydrophobic mutations. by Matthew R. Bowers (8423115)

“…The significant rightward shift in the curve (EC50, non overlapping confidence intervals) indicates a decrease in the apparent Ca²⁺ affinity of neurotransmitter release.…”

Decreased expression of TCA cycle and ETC enzymes in kidneys from rats administered Tl. by Sho Sugahara (11895828)

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SARS-CoV-2 inhibits SG formation and decreases expression of G3BP1. by Stacia M. Dolliver (13822801)

<i>Bbs1</i>^{<i>M390R/M390R</i>} mice have decreased hippocampal proliferation. by Thomas K. Pak (10686881)

“…At P30, mice were started on BrdU injections (2x50mg/kg) for five days. At P44, mice were taken down. …”

Increased levels of PPARγ and decreased levels of adiponectin in thymus from rats administered cocaine for 7 days. by Kana Unuma (283272)

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Multiple-step replication cycle of WT and rgC-A314G (K73R). by You-Yuan Tsai (3142086)

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H2-K^b overexpression decreases NSPC proliferation and impairs adult hippocampal neurogenesis. by Karin Lin (11037548)

Respective increase and decrease in Myc and NRF1/TFAM in kidneys from rats administered Tl. by Sho Sugahara (11895828)

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AIM-100 reduces dsRNA silencing in body wall muscle and decreases DA neurodegeneration. by Anthony L. Gaeta (13272609)

Deep crypt secretory (DCS) cells are predominantly distributed in the proximal colon, with a progressive decrease towards the distal colon. by Daisuke Sugahara (2047696)

VPS34 inhibition decreases intracellular levels of cholesteryl-esters, blocks cholesterol uptake and enhances lysosomal degradation of LDLR. by Marek J. Kobylarz (9292599)

Decreased trigger factor association and increased DnaK association with ribosomes furthers protein homeostasis during Mg²⁺ starvation. by Carissa Chan (18310140)

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Decrease of the DXR-induced genotoxicity and nongenotoxic effects of Theobroma cacao revealed by micronucleus assay by M. F. G. Boriollo (4894975)

Treatment with TDF decreased cell viability and induced morphological changes in hepatic stellate cells. by Sung Won Lee (222509)

M344 decreases orthotopic pancreatic tumor growth when used as a treatment alone or in combination with gemcitabine. by Shelby M. Knoche (13833807)

SWSs measured for cell-laden gels with 5 mg/ml Matrigel and 1 mg/ml (M5C1), 2 mg/ml (M5C2), and 3 mg/ml (M5C3) collagen type I. by Shao-Lun Lu (12360135)

CCR2 depletion decreases lipid accumulation in the liver and WAT. by Seung Joo Lee (1766020)

“…Markedly increased concentration of GOT and GPT in HFD WT was significantly decreased in CCR2 KO. (c) Adiposity size of WAT was measured by Image J software. …”

FTY720 decreased viability, proliferation, and motility and induced apoptosis in human hepatoblastoma cells. by Laura L. Stafman (6577184)

“…<p>(A) Following 24 hours of treatment with FTY720, the viability of HuH6 cells measured using the alamarBlue cell viability assay was significantly decreased (LD₅₀ = 8.4 μM, p ≤ 0.05). …”

Inhibition of PKCδ causes a decrease in viral replication. by Brian D. Carey (6092747)