Δ<i>gra72</i> parasites form bubble vacuoles with decreased PVM permeability to small molecules. by Tatiana C. Paredes-Santos (16699433)

Population dynamics of <i>Killer-Rescue</i>/Cargo, <i>ClvR</i> and split^50cM <i>ClvR</i> V2. by Georg Oberhofer (3401438)

Percentages of inhibition of biofilm formation and eradication of synthesized 1,2,3,5-tetrazine derivatives. by Jean Paul Dzoyem (6424445)

Subjects:

MigC interacts with and decreases the activity of MurD. by Jeanette M. Critchlow (21553796)

Temperature field without considering insulation layer deterioration (2.6 °C). by Jianqing Jia (21001506)

Maximum temperature and freeze-thaw thickness of surrounding rock (2.6 °C). by Jianqing Jia (21001506)

Decreased peritumoral myofibroblasts in the MC38 S.C. tumors of <i>S100a4-Cre; Ext1</i>^<i>f/f</i> mice. by Ayumi Niwa (6256790)

Effect of MI to decrease depressive symptoms (fixed-effects model). by Kalayou Kidanu Berhe (9557751)

Experimental setup of H9c2 cells exposed to normoxia/hypoxia. by Frederik Abel (8452101)

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…The antiproliferative activity of the novel <i>mono</i>- and <i>bis</i>(dimethylpyrazolyl)-<i>s</i>-triazine derivatives was studied against three cancer cell lines, namely, MCF-7, HCT-116, and HepG2. <i>N</i>-(4-Bromophenyl)-4-(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-6-morpholino-1,3,5-triazin-2-amine <b>4f</b>, <i>N</i>-(4-chlorophenyl)-4,6-bis­(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-1,3,5-triazin-2-amine <b>5c</b>, and 4,6-<i>bis</i>(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-<i>N</i>-(4-methoxyphenyl)-1,3,5-triazin-2-amine <b>5d</b> showed promising activity against these cancer cells: <b>4f</b> [(IC₅₀ = 4.53 ± 0.30 μM (MCF-7); 0.50 ± 0.080 μM (HCT-116); and 3.01 ± 0.49 μM (HepG2)]; <b>5d</b> [(IC₅₀ = 3.66 ± 0.96 μM (HCT-116); and 5.42 ± 0.82 μM (HepG2)]; and <b>5c</b> [(IC₅₀ = 2.29 ± 0.92 μM (MCF-7)]. …”

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…The antiproliferative activity of the novel <i>mono</i>- and <i>bis</i>(dimethylpyrazolyl)-<i>s</i>-triazine derivatives was studied against three cancer cell lines, namely, MCF-7, HCT-116, and HepG2. <i>N</i>-(4-Bromophenyl)-4-(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-6-morpholino-1,3,5-triazin-2-amine <b>4f</b>, <i>N</i>-(4-chlorophenyl)-4,6-bis­(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-1,3,5-triazin-2-amine <b>5c</b>, and 4,6-<i>bis</i>(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-<i>N</i>-(4-methoxyphenyl)-1,3,5-triazin-2-amine <b>5d</b> showed promising activity against these cancer cells: <b>4f</b> [(IC₅₀ = 4.53 ± 0.30 μM (MCF-7); 0.50 ± 0.080 μM (HCT-116); and 3.01 ± 0.49 μM (HepG2)]; <b>5d</b> [(IC₅₀ = 3.66 ± 0.96 μM (HCT-116); and 5.42 ± 0.82 μM (HepG2)]; and <b>5c</b> [(IC₅₀ = 2.29 ± 0.92 μM (MCF-7)]. …”

Intracellular Ca²⁺ signaling and IP3R2 expression are decreased in <i>Tcirg1</i>-knockdown osteoclasts. by Dongyan Zhang (640677)

Thermoneutrality decreased sepsis survival. by Goldia Chan (21453340)

<i>clec-4(ok2050)</i> and <i>clec-4(ya1)</i> decrease <i>C</i>. <i>elegans</i> feeding leading to a reduced bacterial load. by Barbara Pees (3313560)

HSF2 reversed the decrease in the MMP induced by Atr. by Wen Wang (6570)

(a) 2D CAD model of tool (b) fabricated tool (c) tool pin geometry. by Shaheer Ahmed Khan (17797647)

Phosphorylation of PFK2 is decreased in cardiomyocytes cultured in the absence of insulin and with diabetes. by Craig A. Eyster (9262632)

Human cerebral organoids treated with VPA show a decreased size, impaired neurogenesis, and induction of senescence in NE cells. by Muriel Rhinn (406515)

C-indexes for the nomograms. by Na Li (6550)

“…Chemotherapy was found to be protective factor for OS (HR = 0.33, 95%CI: 0.30–0.37)/CSS (HR = 0.44, 95%CI: 0.39–0.50) of ovarian cancer patients, while not receiving surgery remained a risk factor. …”

Decrease in the operational range of the enzymatic controller of Fig 51 (in dual-E control mode) as a function to decreased values of the forward enzymatic rate constants <i>k</i><... by Qaiser Waheed (5095328)