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561
Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
Published 2024“…In cardiac muscle, CaM modulates directly or indirectly the activity of several proteins that play a key role in excitation-contraction coupling (ECC), such as ryanodine receptor type 2 (RyR2), l-type Ca2+ (Cav1.2), sodium (NaV1.5) and potassium (KV7.1) channels. Many recent clinical and genetic studies have reported a series of CaM mutations in patients with life-threatening arrhythmogenic syndromes, such as long QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CPVT). …”
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562
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564
The effect of acute ophiobolin A treatment on HO-mediated inflammatory processes
Published 2017“…After 24 h of the administrations, inflammatory mediators such as interleukin-6 (IL-6), tumour necrosis factor-alpha (TNF-) and myeloperoxidase (MPO) enzyme as well as heme oxygenase (HO) activity were measured in both plasma and cardiac tissue, along with serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST). We found that OPA caused a significant elevation in the concentrations of IL-6 and TNF-, increased MPO activity and decreased HO enzyme activity in the plasma. …”
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565
Therapeutic outcomes and biodistribution of gold nanoparticles in collagen-induced arthritis animal model
Published 2022“…CIA rats were then divided into five groups: CIA model (positive control), AuNPs treated- (sphere shape with size: 5, 25, and 75 nm), and methotrexate (MTX)-treated-rats. …”
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566
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567
Burden of disease attributable to suboptimal diet, metabolic risks and low physical activity in Ethiopia and comparison with Eastern sub-Saharan African countries, 1990-2015: findi...
Published 2018“…While the age-adjusted proportion of all-cause mortality attributable to CMU decreased significantly between 1990 and 2015, it increased from 10.8% [95% UI: 8.8-13.3] to 14.5% [95% UI: 11.7-18.0] for dietary risks and from 17.0% [95% UI: 15.4-18.7] to 24.2% [95% UI: 22.2-26.1] for metabolic risks. …”
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568
Propagation rate coefficient for sulfobetaine monomers by PLP-SEC
Published 2016“…The kp values are determined in aqueous solutions for monomer concentrations between 5 and 50 wt % and temperatures between 15 and 80 °C. The propagation rate for SBE is by about a factor of two higher than that for SBAm. …”
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569
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570
Effect of plastic deformation on Corrosion of cadmium in 0.1 m sodium Sulphate solution
Published 1993“…The present investigation was carried out to study the influence of prior plastic deformation and surface finish on the corrosion behaviour of pure cadmium in 0.1 M Na2SC>4 solution at 25° C. Cylindrical specimens were deformed by compression to different levels of deformation up to 90% reduction in height (RH). …”
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571
Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells.
Published 2024“…We assessed the impact of insulin resistance (IR) on metabolic pathways, focusing on genes linked to branched-chain amino acid metabolism, detoxification, and chemotaxis. …”
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572
Progressive circuit resistance training improves inflammatory biomarkers and insulin resistance in obese men
Published 2019“…The data were assessed by two-way repeated measures ANOVA. Results: Body mass, BMI and waist to hip ratio (WHR) were significantly decreased after training intervention (P < .05). …”
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573
Novel Electroless Deposited Corrosion - Resistant and Anti-Bacterial NiP-TiNi Nanocomposite Coatings
Published 2020“…From acidic NiP electroless bath, the co-deposition of TiNi nanoparticles in the NiP matrix to form novel NiP-TiNi nanocomposite coatings (NCCs) on top of API X100 carbon steel using several concentrations of TiNi nanoparticles (0.2, 0.4 and 0.8 g L-1 in the bath) is successfully achieved. …”
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574
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
Published 2024“…For adults, we report the individual and combined prevalence of underweight (BMI <18·5 kg/m2) and obesity (BMI ≥30 kg/m2). …”
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Bryophyte cover and richness decline after 18 years of experimental warming in alpine Sweden.
Published 2020“…Deciduous shrub and litter cover had negative impact on bryophyte cover. We show that bryophyte species do not respond similarly to climate change. …”
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578
Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose
Published 2021“…Primary Human Retinal Endothelial Cells (HRECs) were either pre-treated for 24 h with 1 µM resveratrol or left untreated, then glucose (30 mM) was applied at 3-day intervals for 10 days. qRT-PCR and ELISA were used to detect mRNA or protein expression of endothelial markers (CD31, CDH5, vWF) or mesenchymal markers (VIM, αSMA and collagen I), respectively. …”
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579
Effect of the length of silicon nano-dot/wire on band gap
Published 2014“…We find that the band gap decreases with SNW length for the same diameter and approaches the band gap for an ideal infinitely long SNW. …”
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580
Allelopathic effects of the invasive Prosopis juliflora (sw.) Dc. On seed germination of selected Qatari native plant species
Published 2016“…Dilutions of 2 mgml− 1, 4 mgml− 1, 6 mgml− 1 and 8 mgml− 1 from stock were prepared. …”
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