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point decrease » point increase (Expand Search)
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TUDCA decreases ER stress in HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”
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Four-fold decrease in [H<sup>+</sup>]<sub>e</sub> shifted GLT-1a E<sub>rev</sub> by −18 mV at both low and high glutamate concentrations.
Published 2015“…Arrows show GLT-1a E<sub>rev</sub> shifts. <b>(C)</b> Average GLT-1 E<sub>rev</sub> shifts at 37.5 μM and 600 μM are approximately equal when [H<sup>+</sup>]<sub>e</sub> was decreased from 40 to 10 nM.…”
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Four-fold decrease in [K<sup>+</sup>]<sub>e</sub> shifted GLT-1a E<sub>rev</sub> by +22 mV at both low and high glutamate concentrations.
Published 2015“…Arrows show GLT-1a E<sub>rev</sub> shifts. <b>(C)</b> Average GLT-1 E<sub>rev</sub> shifts at 37.5 μM and 600 μM are approximately equal when [K<sup>+</sup>]<sub>e</sub> was decreased from 44 to 11 mM.…”
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GSK343 treatment decreased <i>in vivo</i> tumor volume and growth.
Published 2021“…<p>SK-N-BE(2) (1.8 × 10<sup>6</sup>) cells were injected subcutaneously into the right flank of 6-week-old, female, athymic nude mice. …”
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