6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…Here, we evaluated the aging and neurodegenerative effects of F-53B using the C. elegans model. After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…Here, we evaluated the aging and neurodegenerative effects of F-53B using the C. elegans model. After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…Here, we evaluated the aging and neurodegenerative effects of F-53B using the C. elegans model. After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…Here, we evaluated the aging and neurodegenerative effects of F-53B using the C. elegans model. After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

Statistics of predicted bandgaps by SVR, GBDT, RF and MLP algorithms based on a 9-dimensional feature space. by Yu Zhang (12946)

Subjects:

<i>Dmxl2</i> knockdown in INS-1E cells decreases glucose-induced insulin release. by Brooke Tata (633065)

“…(B) Seventy-two hours after the transfection of INS-1E cells with <i>Dmxl2-</i>siRNA, <i>Dmxl2</i> mRNA levels had decreased by 75% (error bars: SEM; from three independent experiments). …”

Reproductive transition paralleled a significant decrease in LDH5 and LDH1 expressions in nonTg hippocampus. by Fan Ding (302565)

“…<p>A. NonTg hippocampus demonstrated a an age-related decrease in LDH5 expression from 6 to 15 months of age, which was significant between 6 and 9, 9 and 12 months of age. …”

iC3b level decreases in HCV infected patient sera. by Hangeun Kim (591159)

Inhibition of NLRP3 inflammasomes decreased 5-FU-induced cell death. by Kaya Yoshida (658943)

Simulated response to Ach at activated NALCN channels and decreased phosphodiesterase (PDE) activity in low glucose. by Leonid E. Fridlyand (2636968)

“…<p>(A) PM potentials (V_p); (B) [Ca²⁺]_c and [Ca²⁺]_ER; (C) Cytoplasmic cAMP and IP₃ concentrations. …”

hCDC-derived exosomes significantly decrease cardiomyocyte programed cell death and cause a trend toward increased proliferation of cardiomyocytes <i>in vitro</i> at one week in cu... by Jennifer K. Lang (344441)

Juvenile demyelination leads to a decrease in axonal complexity of PFC PV interneurons. by Sara Hijazi (21656615)

“…</b> Quantification of the overall myelin intensity in PFC of both groups shows a clear loss of myelin in the juvenile demyelination group (<i>t test; n = 6/5 mice per group, ***p < 0.001</i>). …”

Adaptation of SARS-CoV-2_Engl2 to VeroE6 and selection of decreased RDV sensitivity. by Agnieszka M. Szemiel (10196243)

ABT199 inhibits ALK ^mutant kinase activity and decreases it phosphorylation. by Richard Junior Zapata Dongo (17912565)

Exercise decreased the increased expression of cofilin in the cortex during aging. by Yan Li (23143)

Cathepsin B and uPAR knockdown decreases Cdk2 activity and the expression of αVβ3 integrin. by Sreelatha Gopinath (238422)

Prostate cancer incidentally discovered at the time of radical cystoprostatectomy does not decrease overall survival: Results from a large Chinese medical center by Shiying Tang (5137418)

“…Among the 132 patients with PCa, prostate specific antigen (PSA) analysis was available in 76 patients (57.6%), with a median value of 1.06ng/mL, and 61 (80.3%) patients had a PSA value below 4ng/mL. …”

A genetic variant in human FIRE is associated with a decreased interferon response in myeloid cells. by Anaïs Assouvie (9600529)

Fisetin inhibits ER stress in liver of HFD-fed mice. The relative mRNA level of (a) GRP78, (b) eIF2A, (c) ATF4 and (d) CHOP genes was quantified using real-time PCR (n = 5). The in... by Mahboobe Sattari (20622143)

Disruption of the interaction between AKIP 1A and PKAc decreases phosphorylation of p65 at serine 276 in the cytosol. by Charles C. King (156152)