Increased mortality, fungal burden, and inflammation in APN pathway-deficient mice with invasive aspergillosis. by Sri Harshini Goli (20889928)

Image_2_Role of Delta/Notch-like EGF-related receptor in blood glucose homeostasis.jpeg by Nelmari Ruiz-Otero (15424466)

“…DNER loss in adult β-cells in mice (β-Dner cKO mice) disrupted islet architecture and decreased the expression of N-CAM and E-cadherin. β-Dner cKO mice also exhibited impaired glucose tolerance, defects in glucose- and KCl-induced insulin secretion, and decreased insulin sensitivity. …”

Data Sheet 2_ClpB affects biofilm formation in methicillin-resistant Staphylococcus aureus.docx by Miao Yang (328522)

Deciphering the Inhibition of Ethane on Anaerobic Ammonium Oxidation by Xin Tan (721363)

“…Short chain alkanes (C₂–C₈) have been well-known as inhibitors for nitrification through interaction with the ammonia monooxygenase, while whether these alkanes affect anammox is an open question. …”

Cigarette smoke induced autophagy-impairment regulates AMD pathogenesis mechanisms in ARPE-19 cells - Fig 2 by Viren Kumar Govindaraju (4326025)

Expression of structural proteins and calcium pump in the heart after trauma. by Miriam Kalbitz (3150195)

“…B. Decrease in α2-actinin expression 24 h after blunt chest trauma compared to sham procedure. …”

Clinical impact of the two ART resistance markers, K13 gene mutations and DPC3 in Vietnam by Maria Carmina Pau (4775370)

“…</p><p>Results</p><p>The rate of K13(C580Y) ranged from 75.8% in Krong Pa to 1.2% in Huong Hoa district. …”

Table_2_Single-cell RNA sequencing reveals distinct immunology profiles in human keloid.xlsx by Cheng Feng (436816)

“…Furthermore, we found that the immune profiles between two groups varied significantly. The proportion of macrophages in the keloid was significantly elevated compared to the surrounding normal tissue, while cDC2 cells significantly decreased. …”

Chirality Transfer of Stereogenic Boron Centers Enabled by a S_N2‑Type Mechanism by Yannick Stöckl (4184146)

“…In our earlier work, we established a chirality transfer from boron <i>O,N</i>-chelates toward enantioenriched <i>C,N</i>-chelates. This methodology proved to be quite robust, in terms of yields and selectivity. …”

Serp-2 reduces plaque growth in Apolipoprotein E deficient (ApoE^−/−) mice. by Kasinath Viswanathan (132259)

“…A significant reduction in plaque area is detectable with Serp-2 (<b>B,</b> N = 11), but not with CrmA (<b>C,</b> N = 11) treatment compared to saline treated controls. …”

Image_2_Single-cell RNA sequencing reveals distinct immunology profiles in human keloid.tif by Cheng Feng (436816)

“…Furthermore, we found that the immune profiles between two groups varied significantly. The proportion of macrophages in the keloid was significantly elevated compared to the surrounding normal tissue, while cDC2 cells significantly decreased. …”

Ras-like family small GTPases genes in <i>Nilaparvata lugens</i>: Identification, phylogenetic analysis, gene expression and function in nymphal development by Weixia Wang (750235)

“…The expression level of nuclear receptors, Kr-h1, Hr3, FTZ-F1 and E93 involved in 20E and JH signal pathway was impacted in nymphs with silenced twelve <i>NlRSGs</i> individually. The expression of two halloween genes, <i>Cyp314a1</i> and <i>Cyp315a1</i> involved in ecdysone synthesis, decreased in nymphs with silenced <i>NlSar1</i> or <i>NlArf1</i>. …”

Loss of SNX-3 leads to misrouting of hTAC away from the recycling pathway. by Yangli Tian (4871416)

“…****<i>P</i><0.0001 (Student’s <i>t</i> test for M1; <i>t</i> test with Welch’s correction for M2). M1: green pixels overlapping red; M2: red pixels overlapping green. …”

Glibenclamide and quinine differentially modulate the intercellular synchronization of glucose-induced Ca²⁺ oscillations. by Sabine Bavamian (148288)

Hdac3 genetic reduction does not reduce HTT aggregation in R6/2 mouse brain. by Lara Moumné (139215)

“…The same color code (R6/2 = green; Dbl = purple) is used in (A) and (C).…”

Table_1_MYBL2 Gene Polymorphism Is Associated With Acute Lymphoblastic Leukemia Susceptibility in Children.docx by Haixia Guo (8704665)

“…</p>Methods<p>A total of 687 pediatric ALL cases and 971 cancer-free controls from two hospitals in South China were recruited. A case-control study by genotyping three SNPs in the MYBL2 gene (rs285162 C>T, rs285207 A>C, and rs2070235 A>G) was conducted. …”

Mathematical model predictions of k_3eff and R_NOS2. by Jin Nam (206241)

“…Initial values of parameters derived from the equilibrium state for P₀ = 0 were R_P = 0.00944, P_c = 0.000925, P₀ = 0.259127, C = 0.001337, R_I = 0.011025, I_c = 0.020399, I_n = 0.011686, N_c = 0.0000426, R_NOS2 = 0.000616, N_n = 0.000647, N_pc = 0.042536, and N_pn = 0.000274.…”

Image 1_Targeting CCRL2 enhances therapeutic outcomes in a tuberculosis mouse model.tif by Tianyin Wang (10272824)

“…Due to the limited number of antimicrobials in the TB drug discovery pipeline, interest has developed in host-directed approaches to improve TB treatment outcomes. C-C motif chemokine-like receptor 2 (CCRL2) is a unique seven-transmembrane domain receptor that is upregulated by inflammatory signals and mediates leucocyte migration. …”

Image 3_Targeting CCRL2 enhances therapeutic outcomes in a tuberculosis mouse model.tif by Tianyin Wang (10272824)

“…Due to the limited number of antimicrobials in the TB drug discovery pipeline, interest has developed in host-directed approaches to improve TB treatment outcomes. C-C motif chemokine-like receptor 2 (CCRL2) is a unique seven-transmembrane domain receptor that is upregulated by inflammatory signals and mediates leucocyte migration. …”

DataSheet_1_Systemic effects of hypophosphatasia characterization of two novel variants in the ALPL gene.docx by Luis Martínez-Heredia (17722704)

“…The dominant negative effect was analyzed by co-transfection of each variant with the wild-type gene, measuring ALP activity and analyzing cellular localization by flow cytometry.</p>Results<p>Two previously undescribed variants were found in the ALPL gene: leucine 6 to serine missense mutation (c.17T>C, L6S) affecting the signal peptide and threonine 167 deletion (c.498_500delCAC, T167del) affecting the vicinity of the active site. …”