Pravastatin decreases NSPC expansion <i>in vitro</i>. by Ross A. Carson (5184512)

The novel <i>carboxylesterase 1</i> variant c.662A>G may decrease the bioactivation of oseltamivir in humans by Jaeseong Oh (3947381)

“…A novel <i>CES1</i> c.662A>G single nucleotide polymorphism (SNP) was predicted to decrease CES1 enzymatic activity in an <i>in silico</i> analysis. …”

Viral loads of CrPV and DCV across host species during single and coinfection. by Ryan M. Imrie (15810854)

Subjects:

Decreased S100A9 expression alleviates Clostridium perfringens beta2 toxin-induced inflammatory injury in IPEC-J2 cells by Jie Li (13877648)

Viral loads of CrPV and DCV across DGRP lines during single and coinfection. by Ryan M. Imrie (15810854)

Subjects:

dsRNA-induced decrease in Mcl-1 protein expression depends on eIF2α phosphorylation by PKR. by Maikel L. Colli (179059)

Pre-treatment of IOZCAS-Spex-II cells with CPT and HCPT decreased Topo1 specific activity in a dose-dependent manner. by Lan Zhang (90951)

NR2F2 binds the variant rs3743462-C oligonucleotide with higher affinity than the rs3743462-T oligonucleotide and the C-allele is associated with a strong decrease of <i>NR2F2</i> gene expression relative to the T-allele. by Marie Boutant (164748)

<b>Reduced legacy precipitation decreases microbial community growth efficiency and alters soil organic carbon in a California grassland</b> by Linnea Honeker (13113813)

A decrease in circulating CXCR5+CD4+ Tfh cells is associated with HCC progression, and CXCR5+CD4+ Tfh cells are decreased in tumor regions. by Yiqiong Jia (692871)

“…<p>(A) The prevalence of CXCR5+CD4+ Tfh cells decreases with progressive stages in HCC. …”

E2-induced PKCδ activation is responsible for the ASL height decrease in CuFi-1 cells. by Vinciane Saint-Criq (479729)

Downregulation of LGR4 decreases ARPE-19 cell migration. by Qiang Hou (495704)

mTOR inhibition with rapamycin decreases MEC survival and branching. by Meghan M. Morrison (683792)

Autophagy gene knockdown decreases the motility of wild-type and dietary-restricted <i>eat-2</i> animals. by Sara Gelino (3152916)

Annexin A2 accumulates in the nucleus and decreases in the cytoplasm in response to genotoxic agents. by Patricia A. Madureira (114480)

E2 induces increased chromosome conformation capture contact frequencies but decreased proximity between enhancers and promoters. by Luciana I. Gómez Acuña (18605719)

PDGF-BB maintains Bcl2/Bax ratio and decreases caspase-3 activation induced by Tat and morphine. by Shaily Malik (226661)

“…(B) Densitometric analysis of the blots shown in (A). Tat and morphine together resulted in a significantly decreased ratio of Bcl2/Bax, indicating cell's progress towards apoptosis. …”

<i>Ex vivo</i> deletion of <i>sirt1</i> decreases expression of RUNX2 downstream targets. by Kayvan Zainabadi (502381)

“…<b>C)</b> While SIRT1 knockout osteoblasts (Cre) express comparable amounts of Runx2, they show a near two-fold reduction in the expression of the Runx2 downstream target, <u>Osterix</u> (Osx). …”

A New Rotane Family:  Synthesis, Structure, Conformation, and Dynamics of [3.4]-, [4.4]-, [5.4]-, and [6.4]Rotane¹ by Lutz Fitjer (2466634)

“…All syntheses are based on bicyclobutylidene (<b>9</b>):  [2+1] cycloaddition of cyclobutylidene yields [3.4]rotane (<b>5</b>) (<b>9</b>−<b>5</b>), [2+2] cycloaddition of trimethyleneketene followed by spiroalkylation of the resulting trispiroketone <b>10</b> yields [4.4]rotane (<b>6</b>) (<b>9</b>−<b>10</b>−<b>13</b>−<b>14</b>−<b>6</b>), homologization of <b>10</b> via β-hydroxy selenides gives access to tetraspiroketone <b>11</b> and pentaspiroketone <b>12</b> (<b>10</b>−<b>15</b>−<b>11</b>−<b>16</b>−<b>12</b>), and further elaboration directed toward a cyclopropylcarbene−cyclobutene rearrangement yields [5.4]rotane (<b>7</b>) and [6.4]rotane (<b>8</b>) [<b>11</b>(<b>12</b>)−<b>18</b>(<b>24</b>)−<b>19</b>(<b>25</b>)−<b>20</b>(<b>26</b>)−<b>21</b>(<b>27</b>)−<b>22</b>(<b>28</b>)−<b>23</b>(<b>29</b>)−<b>7</b>(<b>8</b>)]. …”

Inhibition of PKC or Rho protein kinase decreases Ad5 wild type replication <i>in vitro</i>. by Alice Liu (4814415)