Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Development of CuAg/Cu2O nanoparticles on carbon nitride surface for methanol oxidation and selective conversion of carbon dioxide into formate by Nazir, Roshan

“…A probable reason may be the strain induced by alloy formation which could favor a reduced coverage of adsorbed hydrogen and a decrease in oxophilicity of the compressively strained copper.…”
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Host genetic variants potentially associated with SARS-CoV-2: A multi-population analysis by Smatti, Maria K.

“…Earlier studies identified single nucleotide polymorphisms (SNPs) associated with SARS-CoV-1 in Eastern Asian (EAS) populations. In this report, we aimed at exploring the frequency of a set of genetic polymorphisms that could affect SARS-CoV-2 susceptibility or severity, including those that were previously associated with SARS-CoV-1. …”
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Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis. by Smatti, Maria K

“…Earlier studies identified single nucleotide polymorphisms (SNPs) associated with SARS-CoV-1 in Eastern Asian (EAS) populations. In this report, we aimed at exploring the frequency of a set of genetic polymorphisms that could affect SARS-CoV-2 susceptibility or severity, including those that were previously associated with SARS-CoV-1. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …”
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Multifunctional self-healing polymeric nanocomposite coatings for corrosion inhibition of steel by Bahgat, Ahmed

“…The electrochemical studies indicate that the corrosion rate of the steel samples coated with the epoxy modified with the healing additives decreases after 5 days of immersion in saline water.…”
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Multifunctional self-healing polymeric nanocomposite coatings for corrosion inhibition of steel by Ubaid F.

“…The electrochemical studies indicate that the corrosion rate of the steel samples coated with the epoxy modified with the healing additives decreases after 5 days of immersion in saline water.…”
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Development And Performance Evaluation Of Smart Polymeric Coatings For Corrosion Protection Of Steel by Khan, Adnan

“…Consequently, they are a promising solution for longer durability of coated piping steel and decreased operation expense. …”
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Corrosion behavior of API-X120 carbon steel alloy in a GTL F-T process water environment at low COD concentration by Ewis, Dina

“…The effect of temperature, time and rotation speed of FT-GTL process water on the corrosion rate of API X-120 carbon steel was investigated. Electrochemical impedance spectroscopy and potentiodynamic polarization techniques were used to determine the carbon steel corrosion rate under temperatures ranging from 293 to 323 K and rotation speed of 0, 500, 1000, 2000 rpm when the immersion time was 0.5, 1, and 2 h. …”
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Soluble ACE2 and Angiotensin II levels Modulated in Hypertensive COVID-19 Patients treated with different Antihypertension Drugs by Yalcin, Huseyin C.

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Evidence of two mechanisms involved in Bacillus thuringiensis israelensis decreased toxicity against mosquito larvae: Genome dynamic and toxins stability by Elleuch, Jihen

“…This bacterium is characterized by a dynamic genome able to win or lose genetic materials which leads to a decrease in its effectiveness. …”
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Microstructure, wear and corrosion characteristics of Cu matrix reinforced SiC–graphite hybrid composites by Jamwal A.

“…Copper matrix composites with SiC-graphite reinforcement (0, 2.5,5, 7.5 and 10 wt.%) were prepared by stir casting process. …”
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Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines by Prabhu K.S.

“…Treatment with GC suppressed constitutively phosphorylated AKT and downregulated expression of inhibitor of apoptotic proteins XIAP, cIAP-1, and cIAP-2. In summation to this, GC-treated leukemic cells upregulated protein expression of pro-apoptotic proteins, Bax with concomitant decrease in expression of anti-apoptotic proteins including Bcl-2 and Bcl-xL. …”
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Investigation of solar PV performance under Doha weather using a customized measurement and monitoring system by Touati, Farid

“…Results predict that the maximum power output from a Poly-crystalline panel decreases by around 30% for a dust exposure of five months. …”
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A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country by Zaghloul, Nancy

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Effects of different diets on glycemic control among patients with type 2 diabetes: A literature review by Al-Adwi, Maryam E.

“…Diet management could improve the elevated HbA1c levels. Aim: This review aims to examine the effects of different types of diets on glycemic control in patients with T2DM. …”
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Mechanical characteristics of ultra-high performance steel FRC made with recycled concrete aggregates by Alnahhal, W.

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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …”
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Simulation and experimental study of underwater dissimilar friction-stir welding between aluminium and steel by Eyvazian, Arameh

“…473 and 573 K for the aluminum and steel sides, respectively) led to sub-stantial refining the grain structure and formation of a thinner IMC layer. …”
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