Table5_Association between OPG polymorphisms and osteoporosis risk: An updated meta-analysis.docx by Xu Han (141301)

“…At the same time, the OPG G1181C polymorphism reduces the risk of osteoporosis (C vs G: OR = 0.84, 95% CI = 0.74–0.95; CC vs GG: OR = 0.75, 95% CI = 0.60–0.93; GC + CC vs GG: OR = 0.80, 95% CI = 0.67–0.95; CC vs GG + GC: OR = 0.84, 95% CI = 0.70–1.00). Moreover, a significantly decreased risk of osteoporosis was also discovered in Asian (C vs G: OR = 0.80, 95% CI = 0.66–0.98; CC vs GG: OR = 0.67, 95% CI = 0.47–0.95; GC + CC vs GG: OR = 0.74, 95% CI = 0.58–0.95) and the female (C vs G: OR = 0.85, 95% CI = 0.75–0.97; CC vs GG: OR = 0.77, 95% CI = 0.61–0.96; GC + CC vs GG: OR = 0.79, 95% CI = 0.66–0.95). …”

Image_5_Potent in vivo efficacy of oral gallium maltolate in treatment-resistant glioblastoma.jpeg by Mona M. Al-Gizawiy (17787488)

“…</p>Results<p>In this study we demonstrate non-invasively, using longitudinal MRI surveillance, the potent antineoplastic effects of GaM in a novel rat xenograft model of trGBM, as evidenced by extended suppression of tumor growth (23.56 mm³/week untreated, 5.76 mm³/week treated, P < 0.001), a blunting of tumor perfusion, and a significant survival benefit (median overall survival: 30 days untreated, 56 days treated; P < 0.001). …”

LRP5 Regulates Development of Lung Microvessels and Alveoli through the Angiopoietin-Tie2 Pathway by Tadanori Mammoto (72440)

“…Here we show that low-density lipoprotein receptor-related protein 5 (LRP5), a component of the Wnt ligand-receptor complex, regulates angiogenesis and alveolar formation in the lung by modulating expression of the angiopoietin (Ang) receptor, Tie2, in vascular endothelial cells (ECs). …”

Image_5_Diatom-Bacteria Interactions Modulate the Composition and Productivity of Benthic Diatom Biofilms.JPEG by Coco Koedooder (5999399)

Nicotine promoted BGC823 cell proliferation through α5-nAChR. by Yanfei Jia (286060)

“…Nicotine promoted cell proliferation in a time-dependent and concentration-dependent relation; B: Treatment of nicotine at the dose of nicotine (0, 1, 10, 100, 500, 1000μM) for 24 hours promoted the expression of α5-nAChR protein in a dose-dependent manner; C: Cells were transfected with α5-nAChR specific siRNA (si-α5) and then treated with nicotine at 100μM for 24 hours. α5-nAChR expressions were significantly decreased compared with scrambled nonspecific control siRNA (si-NC) and Nic (Nicotine) + si-NC group; D: By comparison with the si-NC, transfection with si-α5 considerably inhibited cell proliferation. …”

Image_5_Neonatal Zika virus infection causes transient perineuronal net degradation.TIF by Kaliroi Engel (9755968)

“…These changes were associated with increased expression of matrix metalloproteinase 12 (MMP12) and MMP19, but not MMP9, a disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4) or ADAMTS5. …”

Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals by Zari Dastani (144367)

“…We identified 8 novel loci associated with adiponectin levels and confirmed 2 previously reported loci (<em>P</em> = 4.5×10⁻⁸–1.2×10⁻⁴³). Using a novel method to combine data across ethnicities (N = 4,232 African Americans, N = 1,776 Asians, and N = 29,347 Europeans), we identified two additional novel loci. …”

LpH_V1 exhibits ΔpH dependent gating. by Juan D. Rodriguez (3727345)

“…Except at high pH_o or pH_i, the data are roughly parallel to the reference lines, indicating a slope of 40 mV/unit pH. The slope decreases at pH>8, indicating saturation of ΔpH dependence.…”

Kuwanon V Inhibits Proliferation, Promotes Cell Survival and Increases Neurogenesis of Neural Stem Cells by Sun-Young Kong (249477)

“…KWV treatment of NSCs reduced the phosphorylation of extracellular signal-regulated kinase 1/2, increased mRNA expression levels of the cyclin-dependent kinase inhibitor p21, down-regulated Notch/Hairy expression levels and up-regulated microRNA miR-9, miR-29a and miR-181a. Taken together, our data suggest that KWV modulates NSC fate to induce neurogenesis, and it may be considered as a new drug candidate that can regenerate or protect neurons in neurodegenerative diseases.…”

Brain areas exhibited significantly different FCs with the right V2 in PAs compared with HCs. by Haiyan Qian (706065)

“…The cyan-blue colors indicate increased FC with the right V2 in the PAs versus the HCs, whereas the yellow-red colors indicate decreased FC. …”

In vivo PrP^C expression in AONYS/siRNA-treated mice. by Sylvain Lehmann (372399)

“…A decrease of PrP^C was apparent in siPrP treated mice. …”

Three-Dimensional Methylhydrazinium Lead Halide Perovskites: Structural Changes and Effects on Dielectric, Linear, and Nonlinear Optical Properties Entailed by the Halide Tuning by Dawid Drozdowski (11952504)

Brain areas exhibited significantly different FCs with the left V2 in PAs compared with HCs. by Haiyan Qian (706065)

“…The cyan-blue colors indicate increased FC with the left V2 in the PAs versus the HCs, whereas the yellow-red colors indicate decreased FC for the same comparison (p<0.05, AlphaSim corrected).…”

Equilibrium ratios for the experimental databases. by Federico Sevlever (8934533)

Fucoxanthin ameliorates PM_2.5-mediated skin cell inflammation and senescence by Pincha Devage Sameera Madushan Fernando (21392671)

“…Exposure to particulate matter with a diameter of ≤2.5 µm (PM_2.5) is associated with the occurrence of cardiac disorders, cancer, and senescence. …”

Data_Sheet_5_Intestinal Microbiota Regulate Certain Meat Quality Parameters in Chicken.XLSX by Jiaqi Lei (1428958)

List of IPA-determined "Disease or Cellular Functions" significantly dysregulated by ZIKV infection at 5 dpi. by Mahamud-ur Rashid (3275076)

Data_Sheet_5_Cocktail Therapy of Fosthiazate and Cupric-Ammoniun Complex for Citrus Huanglongbing.docx by Jingwei Duan (9464699)

Video_5_Lateral Hypothalamic GABAergic Neurons Encode and Potentiate Sucrose's Palatability.MP4 by Aketzali Garcia (10013912)

Image_5_Subcutaneous transplantation of human embryonic stem cells-derived pituitary organoids.jpg by Hiroo Sasaki (14703772)