The dose-response curve evolves in time. by Federico Sevlever (8934533)

Loss of Nemp1 leads to the expansion of erythroid progenitors and of early erythroblasts and to stress erythropoiesis. by Didier Hodzic (132944)

2‑Butoxytetrahydrofuran, Isolated from Holothuria scabra, Attenuates Aggregative and Oxidative Properties of α‑Synuclein and Alleviates Its Toxicity in a Transgenic Caenorhabditis... by Sukrit Promtang (18534245)

“…In the present study, we found that 2-BTHF also attenuated the aggregative and oxidative activities of α-synuclein and lessened its toxicity in a transgenic Caenorhabditis elegans (C. elegans) PD model. …”

Image 2_Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages.tiff by Juliana R. Zampieri (22261441)

“…CDK5 is a protein kinase that requires association with regulatory, co-activating proteins, p35 (CDK5R1) or p39 (CDK5R2), for functional activation.…”

Image 1_Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages.tiff by Juliana R. Zampieri (22261441)

“…CDK5 is a protein kinase that requires association with regulatory, co-activating proteins, p35 (CDK5R1) or p39 (CDK5R2), for functional activation.…”

Image 3_Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages.tiff by Juliana R. Zampieri (22261441)

“…CDK5 is a protein kinase that requires association with regulatory, co-activating proteins, p35 (CDK5R1) or p39 (CDK5R2), for functional activation.…”

Image_5_Dual Effects of Cyclooxygenase Inhibitors in Combination With CD19.CAR-T Cell Immunotherapy.tif by Mingya Yang (1655299)

P120ctn isoform 1A restored E-cadherin on the cell membrane and suppressed the invasiveness in H460 cells. by Juanhan Yu (164278)

“…<p>H460 cells were transiently transfected with GFP-siRNA-p120ctn plasmids or with empty vector as control. 24 hours after transfection, an aliquot of the cells was transfected again with p120ctn isoform 1A or 3A cDNA plasmids. (<b>A</b>) Levels and localization of E-cadherin were analyzed by immunofluorescence. …”

P120ctn isoform 1A restored the cytoplasmic E-cadherin levels and enhanced the invasiveness in SPC cells. by Juanhan Yu (164278)

“…<p>SPC cells were transiently transfected with GFP-siRNA-p120ctn or with empty vector as control. 24 hours after transfection, an aliquot of cells was transfected again with p120ctn isoform 1A or 3A cDNA plasmids. (<b>A</b>) Levels and localization of E-cadherin were analyzed by immunofluorescence. …”

Polyclonal HSV-2 IgG antibody response elicited by HSV-2 0ΔNLS, gD-2, or control immunogens. by William P. Halford (202208)

“…(<b>B</b>) Representative immunofluorescent labeling of fixed HSV-2 plaques with a 1∶5,000 dilution of Day 60 serum from each immunization group. …”

Box plots of surface organic layer thickness (a), volumetric soil moisture (b), water stock (c), thaw depth (d), and net seasonal heat input (e) across landscape types and treatmen... by Dana R Nossov (557153)

“…On average, fire caused a five-fold decrease in mean surface organic layer thickness, a doubling of water storage in the active layer, a doubling of thaw depth, an increase in soil temperature at the surface (−0.6 to +2.1 ° C) and at 1 m depth (−1.7 to +0.4 ° C), and a two-fold increase in net soil heat input. …”

RipE1 interacts with NbUCH12 and NbUCH15. by Wenjia Yu (9422059)

Nemp1 localizes at the NE of hematopoietic cells and aggregates at NE openings. by Didier Hodzic (132944)

Image 1_Downregulated PTEN and aberrant JAK–STAT signal pathway in essential thrombocythemia patients.jpeg by Lin Luo (429475)

“…</p>Results<p>The results showed a downregulated PTEN expression in the BM-MNCs of patients with ET, as well as an elevated p-STAT3 expression and a decreased p-STAT5 expression. …”

Table 1_Downregulated PTEN and aberrant JAK–STAT signal pathway in essential thrombocythemia patients.docx by Lin Luo (429475)

“…</p>Results<p>The results showed a downregulated PTEN expression in the BM-MNCs of patients with ET, as well as an elevated p-STAT3 expression and a decreased p-STAT5 expression. …”

Table_1_Differential Effects of Human SP-A1 and SP-A2 on the BAL Proteome and Signaling Pathways in Response to Klebsiella pneumoniae and Ozone Exposure.xlsx by Guirong Wang (124425)

“…We found: that (1) Ozone exposure, but not infection, is a major factor for increases in total BAL protein content. (2) A total of 36 proteins were identified, accounting for 89.62% of the BAL proteins resolved by the 2D-DIGE system. (3) The number of proteins in which levels were altered more than 25% following infection and FA exposure was: SP-A2 > SP-A1 > KO for male mice, and SP-A2 ≈ SP-A1 > KO for female mice. (4) The number of proteins with more than 25% increase/decrease after ozone exposure and infection was: SP-A2 > SP-A1 ≈ KO, with the majority being increases in male mice and decreases in female mice. (5) Eleven out of the 36 proteins, including annexin A5, glutathione S-transferase A4, SP-A1/SP-A2, and 14-3-3 zeta protein, exhibited significant differences among SP-A genotypes. …”

Table_2_Differential Effects of Human SP-A1 and SP-A2 on the BAL Proteome and Signaling Pathways in Response to Klebsiella pneumoniae and Ozone Exposure.xlsx by Guirong Wang (124425)

“…We found: that (1) Ozone exposure, but not infection, is a major factor for increases in total BAL protein content. (2) A total of 36 proteins were identified, accounting for 89.62% of the BAL proteins resolved by the 2D-DIGE system. (3) The number of proteins in which levels were altered more than 25% following infection and FA exposure was: SP-A2 > SP-A1 > KO for male mice, and SP-A2 ≈ SP-A1 > KO for female mice. (4) The number of proteins with more than 25% increase/decrease after ozone exposure and infection was: SP-A2 > SP-A1 ≈ KO, with the majority being increases in male mice and decreases in female mice. (5) Eleven out of the 36 proteins, including annexin A5, glutathione S-transferase A4, SP-A1/SP-A2, and 14-3-3 zeta protein, exhibited significant differences among SP-A genotypes. …”

Table_3_Differential Effects of Human SP-A1 and SP-A2 on the BAL Proteome and Signaling Pathways in Response to Klebsiella pneumoniae and Ozone Exposure.xlsx by Guirong Wang (124425)

“…We found: that (1) Ozone exposure, but not infection, is a major factor for increases in total BAL protein content. (2) A total of 36 proteins were identified, accounting for 89.62% of the BAL proteins resolved by the 2D-DIGE system. (3) The number of proteins in which levels were altered more than 25% following infection and FA exposure was: SP-A2 > SP-A1 > KO for male mice, and SP-A2 ≈ SP-A1 > KO for female mice. (4) The number of proteins with more than 25% increase/decrease after ozone exposure and infection was: SP-A2 > SP-A1 ≈ KO, with the majority being increases in male mice and decreases in female mice. (5) Eleven out of the 36 proteins, including annexin A5, glutathione S-transferase A4, SP-A1/SP-A2, and 14-3-3 zeta protein, exhibited significant differences among SP-A genotypes. …”

Interaction of c-Cbl with Myosin IIA Regulates Bleb Associated Macropinocytosis of Kaposi's Sarcoma-Associated Herpesvirus by Mohanan Valiya Veettil (234371)

“…Phosphorylated c-Cbl colocalized with phospho-myosin light chain II in the interior of blebs of infected cells and this interaction was abolished by c-Cbl shRNA. …”

Distributions of Passenger Patience for the Period 1: (a) Histogram of Taxi Wait Times and PDF of Patience for 1^st Forced Stops in Zone 1; (b) CDFs of Taxi Wait Times an... by Fangyi Yang (18867853)