Effect of IL-17A, IL-17F or IL-22 on TER of cultured ARPE-19 monolayer. by Ying Chen (9697)

“…Incubation of ARPE-19 monolayers with 50 ng/ml IL-17A or IL-17F induced a gradual decrease of TER, and a significant effect occurred 5 days (p = 0.019, p = 0.045) after stimulation. …”

Morphological and molecular analysis of apoptosis in the corpus cavernosum of rats submitted to a chronic alcoholism model by Rogério José de Azevedo Meirelles (7396829)

“…Methods Twenty-four rats were divided into two experimental groups: Control (C) and Alcoholic group (A). …”

Disfavored structures of a GB loop with various three-stranded <i>β</i>-sheets identified by the simulation. by Hiroto Murata (11355849)

“…<p>The structures are categorized according to their register shifts. (A) Conformation of the system V exhibiting inter-atomic collision between the helix and S2’. …”

Image4_ShenQiWan ameliorates renal injury in type 2 diabetic mice by modulating mitochondrial fusion and endoplasmic reticulum stress.PNG by Wei Xiong (58411)

“…This study aimed to investigate the intervention effect and molecular mechanisms of ShenQiWan on renal injury in KKAy mice.</p><p>Methods: C57BL/6J mice (11 weeks old) were fed a regular diet upon arrival, while KKAy mice (11 weeks old) were fed a high-fat diet upon arrival. …”

Image1_ShenQiWan ameliorates renal injury in type 2 diabetic mice by modulating mitochondrial fusion and endoplasmic reticulum stress.TIF by Wei Xiong (58411)

“…This study aimed to investigate the intervention effect and molecular mechanisms of ShenQiWan on renal injury in KKAy mice.</p><p>Methods: C57BL/6J mice (11 weeks old) were fed a regular diet upon arrival, while KKAy mice (11 weeks old) were fed a high-fat diet upon arrival. …”

Image3_ShenQiWan ameliorates renal injury in type 2 diabetic mice by modulating mitochondrial fusion and endoplasmic reticulum stress.PNG by Wei Xiong (58411)

“…This study aimed to investigate the intervention effect and molecular mechanisms of ShenQiWan on renal injury in KKAy mice.</p><p>Methods: C57BL/6J mice (11 weeks old) were fed a regular diet upon arrival, while KKAy mice (11 weeks old) were fed a high-fat diet upon arrival. …”

Polymerization kinetics of <i>Plasmodium</i> actins. by Andrea J. Lopez (4990781)

“…C_c plot of actin I after 1 h (n^b = 2) <b>(a)</b> and 20 h (n^b = 2) <b>(b)</b> of incubation at 4°C, using 0.002 to 10 μM actin. …”

A Systems Biology-Based Gene Expression Classifier of Glioblastoma Predicts Survival with Solid Tumors by Jing Zhang (23775)

“…Validations of prediction performance show that the 23-prognostic gene classifier identified by Method A outperforms other gene classifiers identified by Methods B and C or previously reported for gliomas on 17 of 20 independent sample cohorts across five tumor types. …”

The impact of fishing on a highly vulnerable ecosystem, the case of Juan Fernández Ridge ecosystem - Fig 7 by Javier Porobic (6392612)

“…Note that the y-axes is the ratio of change against the starting conditions—so a -0.5 result indicates a 50% decrease and a 0.5 result indicates a 50% increase -.…”

Validation of key differentially expressed genes. by Yao Li (154923)

Assessment of physiological and electrochemical effects of a repurposed Zinc dithiocarbamate complex on Acinetobacter baumannii biofilms by Obinna Ajunwa (12530125)

“…Among the DTC-metal complexes and DTCs tested, ZnL1 (N-methyl-1-phenyldithiocarbamato-S,S’ Zn(II)), originally designed as an antitumor agent, is effective against biofilm forming <em>A. baumannii.</em> A MIC value of 12.5 µM, comparable to that of Gentamicin (5 µM) was measured for planktonic cells in tryptic soy broth. …”

Reaction Mechanism of Cobalt-Substituted Homoprotocatechuate 2,3-Dioxygenase: A QM/MM Study by Lili Cao (442626)

“…TPSSh predicts barriers of 21.5 versus 12.0 kcal/mol for Co-HPCD/4NC versus Co-HPCD/HPCA, which is consistent with the fact that the rate of the reaction is decreased when the substrate was changed from HPCA to 4NC.…”

Reaction Mechanism of Cobalt-Substituted Homoprotocatechuate 2,3-Dioxygenase: A QM/MM Study by Lili Cao (442626)

“…TPSSh predicts barriers of 21.5 versus 12.0 kcal/mol for Co-HPCD/4NC versus Co-HPCD/HPCA, which is consistent with the fact that the rate of the reaction is decreased when the substrate was changed from HPCA to 4NC.…”

Data_Sheet_2_Hydrolyzed Fat Formula Increases Brain White Matter in Small for Gestational Age and Appropriate for Gestational Age Neonatal Piglets.docx by Megan P. Caputo (8439465)

“…</p><p>Methods: Sex-matched, littermate pairs of SGA (0.5–0.9 kg) and AGA (1.2–1.8 kg) 2 days old piglets (N = 60) were randomly assigned to control (CON) or HF formula diets in a 2 × 2 factorial design. …”

Is rectus abdominis thickness associated with survival among patients with liver cirrhosis? A prospective cohort study by Maria Ciocîrlan (12800283)

“…The patients were followed up for 11.9 ± 5.63 months. RA thickness correlated moderately with MAMC (r = 0. 596; P < 0.0001) and HGS (r = 0.515; P < 0.0001) and decreased with increasing SGA class (A, 10.6 ± 2.8 mm; B, 8.3 ± 1.9 mm; C, 6.5 ± 1.9 mm; P < 0.0001). …”

URE3 motif in promoters of genes modulated by a dominant positive URE3-BP by Carol A. Gilchrist (270735)

“…</p>2<p>These transcripts were decreased in recent clinical isolates <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000282#pntd.0000282-Ehrenkaufer1" target="_blank">[4]</a></p>3<p>Was modestly induced by tetracyclin at below threshold values</p>4<p>These transcripts were increased in recent clinical isolates <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000282#pntd.0000282-Ehrenkaufer1" target="_blank">[4]</a></p>5<p>This probe set recognizes a gene shown to be up regulated in HM-1:IMSS compared to a Rahman strain <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000282#pntd.0000282-MacFarlane1" target="_blank">[3]</a></p>6<p>A signal peptide was found in either the 5′ extended open reading frame or 3′ of initiating ATG, the position of URE3 motif is shown from the newly designated initiating ATG</p>7<p>Annotation on the basis of homology to known sulfotransferases</p>8<p>This transcript was also significantly increased in the EF(2)mutURE3-BPuninduced ameba compared to the uninduced control.…”

Effects of scapulo-humeral training on ultrasonographic and clinical evaluations in stroke: a randomized controlled trial by Özge Onursal Kilinç (21339439)

“…</p> <p>Thirty stroke individuals were randomly separated into two groups as Group I-scapulo-humeral training (5F/10 M) and Group II – control (5F/10 M). Conventional rehabilitation program was applied to both groups, and a scapulo-humeral training exercise protocol was added for the scapulo-humeral group. …”

OroA inhibition of LPS-induced NF-κB activation in lung tissue of the rats. by Tzu-Ling Tseng (288836)

“…<p>LPS treatment (10 mg/kg, iv) significantly decreased cytosolic NF-κBp65 expression in lung tissue (Lane 2 in Fig. 6A) comparing to that by Sal (Saline) followed by Solv (Solvent) treatment (Lane 1 in Fig. 6A). …”

Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with Itself and the CHO Cells That Synthesize It by Dong-Ki Kim (847216)

“…Also, we optimized the composition of the culture medium, and transferred the CHO cells from a spinner culture system to a bioreactor that controlled pH and thereby decreased pH-dependent binding properties of the protein. …”

Effects of 1,25(OH)₂D₃ on transendothelial electrical resistance (TEER) in bEnd.3 cells under hypoxia/reoxygenation (H/R). by Soonmi Won (713581)

“…Values are represented as mean ± s.e.m. <b>(B-C)</b> Pretreatment with vitamin D receptor antagonist pyridoxal 5’-phosphate (P5P) decreased the effect of Vit D (with an observed maximum protective dose of 100 nM) on H/R-induced TEER reduction and 40 kDa FITC-dextran increase in bEnd.3 cell monolayers. …”