In silico screening, molecular docking, and molecular dynamics studies of SNP-derived human P5CR mutants by Peng Sang (611847)

“…<p>Pyrroline-5-carboxylate reductase (P5CR) encoded by <i>PYCR1</i> gene is a housekeeping enzyme that catalyzes the reduction of P5C to proline using NAD(P)H as the cofactor. …”

<i>Pik3ca</i>^<i>d/d</i> mice exhibited a defect of decidualization. by Hye Jin Chang (4779087)

“…(C) Histology of control (a and b) and stimulated (c and d) horn in control (a and c) and <i>Pik3ca</i>^<i>d/d</i> mice (b and d) at day 5.…”

Assessing car-sharing as a circular economy strategy: the case of Taiwan by Hsiu-Ching Shih (2124013)

A novel SNP of <i>MYO1A</i> gene associated with heat-tolerance in Chinese cattle by Yanhong Cao (428443)

Proscillaridin A slows the prostate cancer progression through triggering the activation of endoplasmic reticulum stress by Fan Wang (135182)

The Fn2 and Fn3 repeats of Robo1 are required for sensitivity to Robo2. by Haley E. Brown (4044719)

“…Misexpression of Robo2 (via <i>elav-GAL4</i> and <i>UAS-Robo2</i>) induces strong ectopic midline crossing of FasII-positive axons in embryos that express full length Robo1 (A), Robo1ΔIg2-5 (B), or Robo1ΔFn1 (E). …”

Is serum hemoglobin level an independent prognostic factor for IgA nephropathy?: a systematic review and meta-analysis of observational cohort studies by Kang Zhang (24496)

IP and pairwise Y2H of TgTBC9 reveals Rab2 an interactor. by Justin J. Quan (18516370)

“…(H) Western blot analysis of TgTBC9^AID parasites expressing ^DDV5Rab2 grown in ±IAA as descried in F showing a 52% decrease of Rab2 in IAA-treated parasites. …”

Image2_3D-printed hyaluronic acid hydrogel scaffolds impregnated with neurotrophic factors (BDNF, GDNF) for post-traumatic brain tissue reconstruction.TIF by Tatiana A. Mishchenko (6192452)

“…Interestingly, BDNF-loaded scaffolds promoted the stimulation of neuronal process outgrowth during the first 3 days of cultures development (day 1: 23.34 ± 1.46 µm; day 3: 37.26 ± 1.98 µm, p < 0.05, vs. sham), whereas GDNF-loaded scaffolds increased the functional activity of neuron-glial networks of cultures at later stages of cultivation (day 14) manifested in a 1.3-fold decrease in the duration coupled with a 2.4-fold increase in the frequency of Ca²⁺ oscillations (p < 0.05, vs. sham). …”

E1784K shifts thevoltage-dependence of fast inactivation to more hyperpolarized potentials and accelerates the rate of onset and recovery. by Colin H. Peters (4430245)

“…<p><b>(A1-A4)</b> Sample ionic currents elicited during steady-state fast inactivation recordings from C373F and C373F/E1784K Na_V1.5 at pH 7.4 and pH 6.0. …”

Image_2_Characterization of the Signaling Modalities of Prostaglandin E2 Receptors EP2 and EP4 Reveals Crosstalk and a Role for Microtubules.pdf by Ward Vleeshouwers (10133363)

“…While both EP2 and EP4 signaling leads to an elevation of intracellular cyclic adenosine monophosphate (cAMP) levels through the stimulating Gα_s protein, EP4 also couples to the inhibitory Gα_i protein to decrease the production of cAMP. …”

Schematic diagram illustrating the modes of action of NleC and NleE in host NF-κB suppression. by Hilo Yen (235104)

“…NleC digests activated p65 and to a lesser extent the IκB-bound p65, to decrease the amount of NF-κB available to enter the nucleus, hence reducing the overall host response to the infection.…”

Expression of p23, GR, Fkbp51 and other GR target genes in E18.5 skin. by Marta Madon-Simon (527400)

“…A trend to a reduction of GR levels is suggested by the statistical analysis (p = 0.0566), whereas Fkbp51 levels are undoubtedly decreased in <i>p23</i>^<i>-/-</i> E18.5 epidermis (*** p<0.001). …”

Sex determination genes <i>fru</i> and <i>dsx</i> do not affect body size. by Elizabeth J. Rideout (651946)

Table_5_Infection of Ophiocordyceps sinensis Fungus Causes Dramatic Changes in the Microbiota of Its Thitarodes Host.xlsx by Hua Wu (2707)

“…To explore the microbial involvement in the induction of mycelia-blastospore transition, the microbiota of the hemolymph and gut from Thitarodes xiaojinensis larvae with or without injected O. sinensis blastospores were investigated by culture-dependent and -independent methods. Twenty-five culturable bacterial species and 14 fungal species, together with 537 bacterial operational taxonomic units (OTUs) and 218 fungal OTUs, were identified from the hemolymph and gut of samples from five stages including living larvae without injected fungi (A) or with high blastospore load (B), mummifying larvae without mycelia coating (C), freshly mummifying larvae coated with mycelia (D), and completely mummified larvae with mycelia (E). …”

FACS-panning: gating strategy. by Tim-Henrik Bruun (639181)

“…<p>HEK293T (13×10⁶) cells were transduced at low MOI (0.1) (<b>A</b>) by lentivirus particles derived from a plasmid mixture containing equal amounts of all Env/V3 variants and (<b>B</b>) by separately lentiviral particles each encoding only one of the chimeric Env/V3-variants, respectively. …”

Characteristics of genotypes in Chinese Holstein cattle. by Xu Zhang (49484)

“…R-square decreased quickly with increasing marker distance. …”

Figure 5 from Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells by Stacia L. Koppenhafer (16616290)

“…<b>C,</b> Overlap of proteins downregulated >1.5-fold in the RPPA experiment by romidepsin and panobinostat in Ewing sarcoma (ES6, EW8, and TC71) and osteosarcoma (U2OS) cell lines. …”

Catalytically active USP2a, USP2a^WT, alters MDM2 and cyclin D1 expression. by Jayoung Kim (153487)

“…<p>(<b>A</b>) Enforced expression of wild type USP2a (USP2a^WT) enhances MDM2 level and decreases p53 expression (western blot). …”

Degradation of <i>Alternaria</i> mycotoxins by UV-C irradiation: Effect of selected process and exposure to food components by Yike Han (11323941)

“…The utilization of UV-C radiation appears to be a potentially useful approach for decreasing the underlying risk of <i>Alternaria</i> mycotoxin contamination in foods.…”