Menthol induces large depolarizing currents in TRPM8-transfected neurons. by Devon C. Crawford (256278)

“…Non-transfected neurons did not respond to menthol but always responded with robust currents to KCl at the holding potential of −70 mV. (G) A non-transfected neuron recorded in whole-cell voltage clamp held at 0 mV during 15 s acute application of 100 µM menthol with 100 µM picrotoxin added during the last 5 s. …”

Analytical range of DNA reference standards. by Melinda L. Tursky (20790436)

“…<b>F</b>-G: FLT3-ITD showed a linear relationship across dilutions (F), and a 100% detection rate was observed as low as 0.0031% VAF at a mean depth of 3128 × , though this decreased rapidly at lower VAFs (G). H-I: Variants other than ASXL1:c.1934dup and FLT3:c.2503G > T showed a strong linear relationship (R2 = 0.9979) and Pearson correlation (p < 0.0001, H), with a positive bias at VAF ≤ 0.004 (I). …”

Data_Sheet_1_Associations of lipids and lipid-lowering drugs with risk of stroke: a Mendelian randomization study.ZIP by Hao Qin (113159)

“…The IVW-MR also found a suggestive evidence that decreased LDL-C levels mediated by the PCSK9 (proprotein convertase subtilisin-kexin type 9) gene were associated with a reduced risk of any stroke (AS) (OR, 1.31; 95% CI, 1.13–1.52; p = 0.0003), any ischemic stroke (AIS) (OR, 1.29; 95% CI, 1.10–1.51; p = 0.001), and LAS (OR, 1.73; 95% CI, 1.15–2.59; p = 0.008), while NPC1L1 (Niemann-Pick C1-like protein)-mediated LDL-C levels were associated with a higher risk of small vessel stroke (SVS) (OR, 6.10; 95% CI, 2.13–17.43; p = 0.0008). …”

<i>Tmprss6</i> modulates radiation-induced liver injury through the hepcidin axis and PI3K/AKT pathway by Ya-Li Zhou (21696911)

“…</p> <p>Disruptions in the Matriptase2-hepcidin axis emerge post-total liver radiation, marked by decreased Matriptase2 levels and heightened hepcidin levels. …”

The archaeal RNA chaperone TRAM0076 shapes the transcriptome and optimizes the growth of <i>Methanococcus maripaludis</i> by Jie Li (15030)

“…TRAM0076 unfolded three representative 5′UTR structures <i>in vitro</i> and facilitated the <i>in vivo</i> expression of a mCherry reporter system fused to the 5′UTRs, thus behaving like a transcription anti-terminator. …”

Data_Sheet_1_Foot Pronation Contributes to Altered Lower Extremity Loading After Long Distance Running.PDF by Qichang Mei (725612)

“…<p>This study presents an investigation of the changes in foot posture, joint kinematics, joint moments and joint contact forces in the lower extremity following a 5 k treadmill run. A relationship between knee and ankle joint loading and foot posture index (FPI) is developed. …”

Statistical analysis of interspike intervals (ISI). by Gregor Moenke (108193)

“…<p>(A) The average ISI decreases with the concentration ( = 5) and with ( = 1 ). …”

Fluoride varnishes with calcium glycerophosphate: fluoride release and effect on in vitro enamel demineralization by Thiago Saads CARVALHO (5789396)

“…<div><p>The aims of this study were (1) to assess the amount of fluoride (F) released from varnishes containing calcium glycerophosphate (CaGP) and (2) to assess the effect of the experimental varnishes on in vitrodemineralization. Six test groups using 5 varnishes: base varnish (no active ingredients); Duraphat® (2.26% NaF); Duofluorid® (5.63% NaF/CaF2); experimental varnish 1 (1% CaGP/5.63% NaF/CaF2); experimental varnish 2 (5% CaGP/5.63% NaF/CaF2); and no varnish were set up. …”

Alteration of Ubiquitination in the Brain of ENOPH1 Knockout Mice after Early Ischemic Stroke by Yike Wu (20982007)

“…Hence, the present study explored changes in the ubiquitinomic in early ischemic brain tissues between wildtype and ENOPH1 knockout mice using a comprehensive quantitative analysis. Our results showed that 4000 ubiquitination-modified sites in 1613 proteins were quantified, with 772 ubiquitinated sites in 464 proteins significantly decreasing or increasing after ENOPH1 knockout (fold change >1.5 or <1/1.5, <i>p</i> < 0.05). …”

Image_1_The Characteristic of Critical Genes in Neuroendocrine System and Their Regulation on Food Habit Transition and Metamorphosis of Veined Rapa Whelk Rapana venosa (Valencienn... by Mei-Jie Yang (8978381)

“…Additionally, expression of the three genes was decreased after metamorphosis, while Rv-NOS and Rv-CCKR were increasingly expressed in competent larvae, which may help the larvae find suitable environments and promote digestive system development for metamorphosis, and the result of 5-HT IHC analysis also reflects the development of neuroendocrine system. …”

Image_2_Blunted perception of breathlessness in three cases of low grade insular-glioma.JPEG by Tom P. Chapman (17946875)

“…Patients rated air-hunger on a visual analogue scale (VAS). Patients had lower stimulus–response (2.8 ± 2 vs. 11 ± 4 %VAS/mmHg; p = 0.004), but similar threshold (40.5 ± 3.9 vs. 43.2 ± 5.1 mmHg), compared to healthy individuals. …”

Image2_Transcriptional regulation of Satb1 in mouse trophoblast stem cells.TIF by Wei Yu (43094)

“…Knockdown of ELF5 downregulated Satb1 expression in TS cells and overexpression of ELF5 increased the enhancer-reporter activity. …”

Image_1_Blunted perception of breathlessness in three cases of low grade insular-glioma.JPEG by Tom P. Chapman (17946875)

“…Patients rated air-hunger on a visual analogue scale (VAS). Patients had lower stimulus–response (2.8 ± 2 vs. 11 ± 4 %VAS/mmHg; p = 0.004), but similar threshold (40.5 ± 3.9 vs. 43.2 ± 5.1 mmHg), compared to healthy individuals. …”

Image1_Transcriptional regulation of Satb1 in mouse trophoblast stem cells.TIF by Wei Yu (43094)

“…Knockdown of ELF5 downregulated Satb1 expression in TS cells and overexpression of ELF5 increased the enhancer-reporter activity. …”

Alteration of Ubiquitination in the Brain of ENOPH1 Knockout Mice after Early Ischemic Stroke by Yike Wu (20982007)

“…Hence, the present study explored changes in the ubiquitinomic in early ischemic brain tissues between wildtype and ENOPH1 knockout mice using a comprehensive quantitative analysis. Our results showed that 4000 ubiquitination-modified sites in 1613 proteins were quantified, with 772 ubiquitinated sites in 464 proteins significantly decreasing or increasing after ENOPH1 knockout (fold change >1.5 or <1/1.5, <i>p</i> < 0.05). …”

Table_1_The Characteristic of Critical Genes in Neuroendocrine System and Their Regulation on Food Habit Transition and Metamorphosis of Veined Rapa Whelk Rapana venosa (Valencienn... by Mei-Jie Yang (8978381)

“…Additionally, expression of the three genes was decreased after metamorphosis, while Rv-NOS and Rv-CCKR were increasingly expressed in competent larvae, which may help the larvae find suitable environments and promote digestive system development for metamorphosis, and the result of 5-HT IHC analysis also reflects the development of neuroendocrine system. …”

Table_3_The Characteristic of Critical Genes in Neuroendocrine System and Their Regulation on Food Habit Transition and Metamorphosis of Veined Rapa Whelk Rapana venosa (Valencienn... by Mei-Jie Yang (8978381)

“…Additionally, expression of the three genes was decreased after metamorphosis, while Rv-NOS and Rv-CCKR were increasingly expressed in competent larvae, which may help the larvae find suitable environments and promote digestive system development for metamorphosis, and the result of 5-HT IHC analysis also reflects the development of neuroendocrine system. …”

DataSheet1_Transcriptional regulation of Satb1 in mouse trophoblast stem cells.PDF by Wei Yu (43094)

“…Knockdown of ELF5 downregulated Satb1 expression in TS cells and overexpression of ELF5 increased the enhancer-reporter activity. …”

Supplementary Material for: Physical Activity and Gastric Residuals as Biomarkers for Region-Specific NEC Lesions in Preterm Neonates by Cao M. (4161253)

“…<b><i> Methods:</i></b> Cesarean-delivered preterm pigs were fed parenteral nutrition and increasing amounts of formula for 5 days after birth (n = 120). Their physical activity was quantified by a continuous camera surveillance system and they were evaluated twice daily for clinical signs of apathy, discoloration, respiratory distress, abdominal distension and diarrhea. …”

Halogenated Symmetrical Tetraazapentacenes: Synthesis, Structures, and Properties by Jens U. Engelhart (1393285)

“…The targets were obtained by thermal condensation of 2,5-dihydroxyquinone with 4,5-dichloro-, 2,6-dichloro-, and 4,5-dibromo-1,2-phenylenediamine, followed by oxidation with hot acidic dichromate. …”