Developmental and Neurobehavioral Toxicity of Hexaphenoxycyclotriphosphazene: Implications for Its Safety as a Flame-Retardant Alternative to Triphenyl Phosphate by Ruobing Bai (4860043)

“…HPCTP caused dose-dependent depression-like behaviors (hypoactivity, light-zone avoidance) through suppression of serotonin 1A (5-HT₁A) signaling, supported by decreased <i>htr1aa</i> expression and serotonin levels and partially rescued by the 5-HT₁A receptor agonist 8-OH-DPAT. …”

Activation of ICE<i>Bs1</i> that is unable to excise causes DNA damage. by Saria A. McKeithen-Mead (3216084)

Image_2_Hereditary Xerocytosis: Differential Behavior of PIEZO1 Mutations in the N-Terminal Extracellular Domain Between Red Blood Cells and HEK Cells.JPEG by Yohei Yamaguchi (716799)

“…How these PIEZO1 mutations impair channel function and alter red blood cell (RBC) physiology, is not completely understood. Here, we report the characterization of mutations in the N-terminal part of the protein (V598M, F681S and the double mutation G782S/R808Q), a part of the channel that was subject of many investigations to decipher its role in channel gating. …”

Image_2_Hereditary Xerocytosis: Differential Behavior of PIEZO1 Mutations in the N-Terminal Extracellular Domain Between Red Blood Cells and HEK Cells.JPEG by Yohei Yamaguchi (716799)

“…How these PIEZO1 mutations impair channel function and alter red blood cell (RBC) physiology, is not completely understood. Here, we report the characterization of mutations in the N-terminal part of the protein (V598M, F681S and the double mutation G782S/R808Q), a part of the channel that was subject of many investigations to decipher its role in channel gating. …”

Nitrate anomaly series. by Antonio Bode (1473376)

Salivary indicator changes after acid stimulation in HCG and MG. by Ye Huang (1482538)

A presumptive schematic about the mechanism underlying the ability of M₄N combination treatment to induce tumoricidal activity. by Kotohiko Kimura (1888807)

Effect of alcohol on bone marrow immune activity in female and male rats. by Ming Cheng (494553)

Timeline of in vivo and in vitro assessment of phospho-signals before formalin-fixation. by Patrick N. Harter (539466)

Shorter sleep durations in adolescents reduce power density in a wide range of waking electroencephalogram frequencies by Irwin Feinberg (6250919)

“…<div><p>Despite sleep’s recognized biological importance, it has been remarkably difficult to demonstrate changes in brain physiology with reduced sleep durations. In a study of adolescents, we varied sleep durations by restricting time in bed for four nights of either 10, 8.5 or 7 h. …”

Lactadherin Inhibits Secretory Phospholipase A₂ Activity on Pre-Apoptotic Leukemia Cells by Steffen Nyegaard (475969)

“…Lactadherin inhibited 45% of activity of <i>Naja mossambica</i> sPLA₂ and >70% of human secretory phospholipase A₂-V on the membranes of human NB4 leukemia cells treated with calcium ionophore A23187. …”

Data_Sheet_1_Serotonin Alters the Phase Equilibrium of a Ternary Mixture of Phospholipids and Cholesterol.docx by Oskar Engberg (1620424)

“…The small aromatic neurotransmitter serotonin (5-HT) has been found to bind to membranes. We studied the lipid structure and packing of a ternary membrane mixture consisting of palmitoyl-oleoyl-phosphatidylcholine, palmitoyl-sphingomyelin, and cholesterol at a molar ratio of 4/4/2 in the absence and in the presence of 5-HT, using a combination of solid-state ²H NMR, atomic force microscopy, and atomistic molecular dynamics (MD) simulations. …”

DataSheet_1_Possible Genetic Determinants of Response to Phenytoin in a Group of Colombian Patients With Epilepsy.pdf by Carlos Alberto Calderon-Ospina (8803778)

“…</p>Objective<p>Our objective was to assess the impact of some genetic factors and its possible association with treatment response and adverse drug reactions (ADRs) to phenytoin in 67 adult Colombian patients with epilepsy.</p>Methods<p>We conducted an analytical, observational, prospective cohort study to screen four polymorphisms in pharmacogenes: CYP2C9*2-c.430C>T (rs1799853), CYP2C9*3-c.1075A>C (rs1057910), ABCB1-c.3435T>C (rs1045642), and SCN1A-IVS5-91G>A (rs3812718), and their association with treatment response. …”

Supplementary Material for: Hypofractionated Radiotherapy for Anaplastic Thyroid Carcinoma: 15 Years of Experience in a Single Institution by Takahashi N. (4478392)

“…<b><i>Methods:</i></b> Thirty-three patients who received radiotherapy for ATC between January 2000 and December 2014 were retrospectively included. We defined hypofractionated radiotherapy as a single dose ≥5 Gy. …”

Magnetic Resonance Spectroscopic Imaging and Volumetric Measurements of the Brain in Patients with Postcancer Fatigue: A Randomized Controlled Trial by Hetty Prinsen (457153)

“…Patients in the therapy group reported a significant larger decrease in fatigue scores than patients in the waiting list group.…”

Spatio-temporal variability of surface chlorophyll-a in the Halmahera Sea and its relation to ENSO and the Indian Ocean Dipole by R. Y. Setiawan (6950732)

SlowFaster, a user-friendly program for slow-fast analysis and its application on phylogeny of -1 by Martin Kostka (95963)

“…Bootstraps of other nodes did not change dramatically. Except for our five new isolates (GERA3A, GERA3B, GEPA2, GECA2, KINIX2), isolates are labeled with accession numbers of their SSU rRNA gene sequences.…”

SlowFaster, a user-friendly program for slow-fast analysis and its application on phylogeny of -0 by Martin Kostka (95963)

“…Bootstraps of other nodes did not change dramatically. Except for our five new isolates (GERA3A, GERA3B, GEPA2, GECA2, KINIX2), isolates are labeled with accession numbers of their SSU rRNA gene sequences.…”

MST1/2 in PDGFR-a+ cells negatively regulates TGF-β-induced Myofibroblasts Accumulation in Renal Fibrosis by Yina An (11511342)

The role of endoscopic doppler probe in the management of bleeding peptic ulcers: a systematic review and meta-analysis by Abhishek Bhurwal (9766157)

“…The endoscopic doppler probe (DOP-US) identifies arterial blood flow at the base to direct therapy. We performed a systematic review and meta-analysis to evaluate the role of the DOP-US in bleeding peptic ulcers.…”