Effects of MβCD and MβCD + cholesterol on intracellular calcium. by Mohammed Z. Haque (3148443)

“…<p>(5A) Diastolic and systolic Fluo-4 fluorescence values. (5B) Maximal rate of Fluo-4 increase during systole, and (5C) maximal rate of Fluo-4 decrease during diastole. * p<0.05 vs. control, n = 20–30/group.…”

Gene expression of VEGF in laser capture microdissected airways (bronchioles) (8A) and parenchyma (8B). by Steven Zhou (440982)

“…<p>VEGF is believed to be a trophic factor for normal lung parenchymal maintenance and is decreased old compared to young animals. …”

Image_1_Management Scenarios Under Climate Change – A Study of the Nordic and Barents Seas.TIFF by Cecilie Hansen (2927607)

“…<p>The effects of increasing fishing pressure in combination with temperature increases in the Nordic and Barents Seas have been evaluated using an end-to-end model for the area forced by a downscaled RCP 4.5 climate scenario. The scenarios that have been applied have used four different fractions of fisheries mortality at maximum sustainable yield (Fmsy); 0.6, 0.8, 1.0 and 1.1 × Fmsy. …”

Nutrient dynamic in cocoa leaves under different nitrogen sources: a reference tool for foliar analysis by Melissa Alexandra Romero (14005255)

“…However, basic information concerning the movement of nutrients in leaves over time is still unknown, and methods to find an optimal time to collect a sample are still ambigu-ous. The present work focused on describing the movement of foliar nutrients (N, P, K, Ca and Mg) in productive 5-year-old cocoa clone CCN51 plants at the same dose of 114.8 kg ha-1 under different sources of nitrogen fertilization (Urea, calcium ni-trate, ammonium sulfate and a control without application). …”

Table_1_Management Scenarios Under Climate Change – A Study of the Nordic and Barents Seas.DOCX by Cecilie Hansen (2927607)

“…<p>The effects of increasing fishing pressure in combination with temperature increases in the Nordic and Barents Seas have been evaluated using an end-to-end model for the area forced by a downscaled RCP 4.5 climate scenario. The scenarios that have been applied have used four different fractions of fisheries mortality at maximum sustainable yield (Fmsy); 0.6, 0.8, 1.0 and 1.1 × Fmsy. …”

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)

“…Moreover, MALAT1 knockdown dramatically suppressed oleic-induced lipid accumulation in HepG2 cells. Interestingly, knocking down MALAT1 significantly reduces the expression of CD36 in steatosis HepG2 cells in the presence of Ex-4. …”

A Proof-Of-Principle Study of Epigenetic Therapy Added to Neoadjuvant Doxorubicin Cyclophosphamide for Locally Advanced Breast Cancer by Claudia Arce (42941)

“…One of 15 operated patients (6.6%) had pathological CR and 70% had residual disease <3 cm. There was a statistically significant decrease in global 5^mC content and HDAC activity. …”

datasheet1_Investment Planning Methodology for Complex Urban Energy Systems Applied to a Hospital Site.pdf by Bastien Bornand (9749414)

“…The results show that among the four scenarios identified, the most optimistic alternative allows to decrease the final energy consumption of about 36%, cut the CO₂ emissions by a half, multiply the renewable energy share by a factor 3.5 while reducing the annual total cost by 24%. …”

Quantitative comparison between network model results (bars) and experimental data (shown as point estimates (filled black circles) and 95% credible intervals (error bars) for the... by Ana C. Estrada (8917370)

“…<p>a) The signaling network model quantitatively captured increases in expression of mTORC1-associated species (p-S6K, p-S6, and p-4EBP1) caused by <i>Tsc1</i> knock-out. b) The network model quantitatively captured the decrease in p-AKT and contractile proteins (SMMHC, SMA, and SM22) caused by <i>Tsc1</i> KO. c) Simulated inhibition of mTORC1 with rapamycin quantitatively captured the decrease in p-S6K and p-S6 activation and the decrease in contractile proteins observed experimentally. d) The network model quantitatively captured the increase in MMP2 expression and decrease in extracellular matrix transcripts <i>Col3a1</i> and <i>Eln</i> seen experimentally after <i>Tsc1</i> KO. e) The network model quantitatively captured the experimentally measured increases in lysosome-related proteins (β-catenin, LAMP1/2, and MITF) due to <i>Tsc1</i> KO. f) Inhibition of mTORC1 with rapamycin caused a decrease in lysosome-related species, which the network model captured qualitatively but not quantitatively. …”

Table_2_The F-Box Protein Fbp1 Regulates Virulence of Cryptococcus neoformans Through the Putative Zinc-Binding Protein Zbp1.docx by Lian-Tao Han (8888273)

rAAV1/2 EmGFP miR499 reduces relaxin-3-like immunoreactivity from one week post infusion. by Gabrielle E. Callander (145796)

“…<p>EmGFP (green) is expressed in cells transduced by rAAV1/2 EmGFP miR499. Relaxin-3-like immunoreactivity (red) in the nucleus incertus decreases as transgene expression increases from 1 week (A), 3 weeks (B), 6 weeks (C) and 9 weeks (D) post infusion. n = 4 rats for each time point. …”

Image_1_Corrected Serum Ionized Calcium as a Risk Factor Related to Adult Dyslipidemia.JPEG by Ke Yun (12325793)

“…High [Ca2+]corr levels were positively associated with elevated TC, LDL-C, and Non-HDL-C but inversely associated with decreased HDL-C odds. …”

<i>In vivo</i> anti-tumor effects of 3-BP, sorafenib, and a combination treatment in xenograft nude mice bearing AR Huh-BAT cells. by Minjong Lee (597002)

“…(E) After matrix detachment, anoikis-resistant cancer cells decrease intracellular ROS levels through inducing enzymes involved in the glycolysis and antioxidant systems for their survival. …”

Data Sheet 1_Case series: Effects of a ketogenic diet on cardiometabolic health in seven outpatients with bipolar disorder.pdf by Louis Schreel (22385035)

“…</p>Results<p>Beneficial cardiometabolic effects included a decrease in mean Lp(a) of 6.6 mg/dl (−21%), a reduction in mean triglyceride of 40.6 mg/dl (−30%), a reduction in mean apoB of 0.14 g/L (−10,5%) and an increase in mean HDL-C of 3 mg/dL (+5%), a reduction in mean hsCRP of 0.94 mg/L (−45%), a reduction in mean TNF-α of 1.31 pg/ml (−7%), a reduction in mean MDA-LDL of 36.77 U/L (−38%), a reduction in mean nitrotyrosine of 225 nmol/L (−28%), a mean weight reduction of 4 kg (−4,6%), a mean visceral fat reduction of 0.69% (−10%) and a mean fat mass reduction of 3.7 kg (−12%). …”

The anchoring mechanism of CaMKII for electrical remodeling in heart failure by rui Feng (11948444)

“…The expressions of CACNA1C (CaV1.2), SCN5A (NaV1.5), and KCNH2 (hERG) were down-regulated, ,and we confirmed that the three genes were closely related to native CaMKⅡ and CaM by protein-protein interaction network analysis. …”

Data_Sheet_1_Contribution of the EnvZ/OmpR two-component system to growth, virulence and stress tolerance of colistin-resistant Aeromonas hydrophila.pdf by Gang Xiao (568764)

“…Under non-stress conditions, the 23-C-23:ΔEnvZ/OmpR strain showed a significant decrease in growth rate compared to that of 23-C-23. …”

Natural Form of Noncytolytic Flexible Human Fc as a Long-Acting Carrier of Agonistic Ligand, Erythropoietin by Se Jin Im (204954)

“…Moreover, the mean serum half-life of EPO-hyFc(H), a high sialic acid content form of EPO-hyFc, was approximately 2-fold longer than that of the heavily glycosylated EPO, darbepoetin alfa, in rats. …”

<i>Mdx</i> diaphragms exhibit a clear progression of muscular dystrophy as mice age. by Catherine C. Henry (4416760)

“…D, M, V: dorsal, midcostal, and ventral regions. Values are means ± SD.…”

B-1CDP cells from IL-10 deficient mice are more competent to control <i>L</i>. <i>major</i> infection. by Angélica F. Arcanjo (733345)

Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa by Lin Li (28817)

“…<i>Clcc1</i>^<i>+/-</i> KO mice showed decreased ERGs and photoreceptor number. Together these results strongly suggest that intracellular chloride transport by CLCC1 is a critical process in maintaining retinal integrity, and CLCC1 is crucial for survival and function of retinal cells.…”