Fluorescence emission of human plasminogen (280 nm excitation). by Manuel Correia (113666)

“…Fitting of the experimental trace obtained with emission fixed at 330 nm and 405 nm was carried out using an exponential function <i>F(t)</i> = <i>C</i>1– <i>C</i>2.e^-<i>kt</i>. The fitted parameter values and corresponding errors, and root mean square error values were obtained after fitting the kinetic trace (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116737#pone.0116737.t005" target="_blank">Table 5</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116737#sec002" target="_blank">Materials and Methods</a>).…”

AuNP functionalization. by Joan Comenge (126915)

“…(b) When an excess of drug was introduced, the MUA charge became progressively quenched, which lead to aggregation of AuNPs, as denoted by the red-shift and further intensity decrease of SPR intensity in less than one hour. (c) Red-shift of the SPR peak at the working conditions: the initial peak of citrate-capped AuNPs shifted from 515 nm to 521.5 nm after MUA conjugation and to 523 nm after cisplatin conjugation. …”

Merlin loss increases SC NPC growth, glial differentiation and cell survival. by Cynthia Garcia (562261)

“…<p><i>Nf2</i> loss results in a (<b>A</b>) 1.8-fold increase in neurosphere diameter (p<0.0001; two-tailed Mann-Whitney U-test), (<b>B</b>) 3.6-fold increase in cell number at day 8 (p<0.001; 2-way ANOVA), and (<b>C</b>) a 1.7-fold increase in clonogenic expansion relative to WT SC NPCs (p = 0.003; two-tailed; two-tailed Mann-Whitney U-test). …”

Simulations suggest spatial confinement causes the late-stage rearrangement of sarcolytes. by Daiki Wakita (8080223)

“…<p>Parameter changes to slow down the muscle units were performed from 30 to 50 hAPF (steps 129,600–273,600). (a–e) Snapshots of the left halves of simulation fields at 40 and 50 hAPF: (a) spatial confinement, (b) decrease in the self-propelling force strength of hemocytes, (c) increase in the friction coefficient of all the particles, (d) increase in the adhesion strength between a hemocyte and a fat body cell, (e) increase in the adhesion strength between hemocytes. …”

Measurement of apoptosis in CTLA4-downregulated low CD38/high CTLA4 CLL cells. by Amit K. Mittal (440288)

“…Panel F: Mean expression of Bcl-2 in (low CD38) patient samples (n = 3) treated with and without CTLA4-siRNA. β-Actin was used as a control.…”

Dependence of motif coefficients on the time course of STDP and time course of post synaptic currents. by Neta Ravid Tannenbaum (2940351)

“…<b>C</b>. The correlation function induced by the third order motif {2, 1} peaks at a similar time as in A, because in both motifs <i>α</i> − <i>β</i> = 1, meaning that the paths leading to neurons <i>i</i> and <i>j</i> differ in length by one synapse. …”

Mitochondrial OXPHOS activity of ATZ-treated rat skeletal muscle mitochondria. by Soo Lim (172772)

“…(B) Decrease in OCR of complex II plus III in ATZ300-treated skeletal muscle mitochondria (n = 5). …”

Competition among epitope-specific CD8 T cells occurs in the central nervous system following acute infection with TMEV-OVA. by Courtney S. Malo (798045)

“…After one week, brain-infiltrating lymphocytes were harvested and stained for surface markers and peptide:MHC tetramer. (A) Representative flow cytometry plots and (B, C) quantified peptide:MHC tetramer⁺ cells of CD8α⁺CD45^hi cells per brain demonstrate a significant decrease in CD8 T cells recognizing VP2_121-130 upon vector silencing. …”

Spike rate ratio was lower in <i>rd10</i> than in wild type retina. by Christine Haselier (576439)

“…Each mean is marked by a cross. B: Data from PNW20 wild type and <i>rd10</i> mice are shown. …”

Dynamics of biofilm formation on mucus. by Tamara Rossy (11967337)

“…The distances were normalized to the initial time point. They decrease over time, indicating contraction of the mucus patch. t₁, t₂, t₃ refer to the time points shown in panel c. …”

Influence of VEGF165 and HGF gene delivery on monocyte infiltration of peri-infarct area. by Pavel I. Makarevich (5249657)

“…Student’s t-test (n = 4/group): *significant increase of CD68+ cells density (p<0.05 vs. “pC4W” negative control); **significant decrease of CD68+ cells density (p<0.05 vs. …”

Carotenoids, sugars, ascorbic acid, total phenolics, and antioxidant activity of murici from Brazilian Cerrado during refrigerated storage by Celso Martins Belisário (8651982)

“…This study characterized the fruits of the muricizeiro shrub (Byrsonima crassifolia, Malpighiaceae), which were harvested from native plants on private properties and stored for 16 days at a mean temperature of 12 °C. The fruits were evaluated during storage for: 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, ascorbic acid content, phenolics and carotenoids total, carotenoids profile, glucose, fructose and sucrose contents. …”

Diurnal variability in sea surface temperature characterised from drifting buoy day by Christopher J Merchant (511163)

“…<p>Drifting-buoy sea surface temperature (SST) records have been used to characterise the diurnal variability of ocean temperature at a depth of order 20 cm. We use measurements covering the period 1990-2009 from the International Comprehensive Ocean-Atmosphere Data Set (ICOADS) version 2.5, which is a collection of marine surface observations that includes individual SST records from drifting buoys. …”

Expression of integrins in retinal AC under different glucose conditions. by Eui Seok Shin (151716)

“…<p>Integrins α5β1 (A) and αvβ3 (B) levels were determined by FACS analysis. …”

Schematic representation of dsRNA- and virus-induced beta cell apoptosis. by Maikel L. Colli (179059)

“…<b>1</b>) Cytoplasmic dsRNA activates the kinase PKR that in turn phosphorylates the elongation factor eIF2α; <b>2</b>) phosphorylation of eIF2α leads to inhibition of protein translation with consequent decrease of Mcl-1 expression; <b>3</b>) reduction of Mcl-1 protein increases unbound Bim, which activates BAX; <b>4</b>) BAX translocates to the mitochondria; <b>5</b>) BAX oligomerizes and induces permeabilization of the mitochondrial outer membrane, allowing the release of cytochrome <i>c</i> to the cytoplasm; <b>6</b>) cytoplasmic cytochrome <i>c</i> forms complexes with Apaf1 and activates the initiator caspase 9; <b>7</b>) finally, caspase 9 cleaves and activates the executioner caspase 3, <b>8</b>) triggering the final steps of beta cell apoptosis; <b>9</b>) further studies are required to clarify additional pathways implicated in virus-induced beta cell apoptosis.…”

Perifosine targets the Aldefluor-positive cell population in breast cancer xenografts. by Hasan Korkaya (159560)

“…<p>(A–C). 50,000 cells from SUM159 cell line or two breast cancer xenografts, MCI, or UM2 were injected into NOD/SCID mice and the tumor size was monitored. …”

Cell counts in different retinal layers for zebrafish exposed to MNU at baseline and follow-up. by Christoph Tappeiner (444164)

“…MNU 150 mg/l group: Rod cell loss started at day 5; the number of rods was lowest at day 8 (p≤0.01) with a decrease of 79.6%, but fully recovered by day 60. …”

Germline expression of <i>lin-35(+)</i> rescues <i>lin-35</i> mutant fertility defects. by Brian P. Mikeworth (16274376)

“…(B) The decrease in fertility with moderate temperature stress represented by the percentage of the mean brood size remaining under upshift conditions compared to growth at 20°C within the same strain. …”

Inhibition of KDM expression <i>in vivo</i>. by Hanitriniaina Rabeony (596171)

“…<p>(A) Ears from C57Bl/6 mice were injected intradermally with 250 ng of IL-1α, IL-17A, IL-22, OSM and TNFα (M5) or with Phosphate Buffered Saline (PBS). …”

File S1 - Novel NAC Transcription Factor TaNAC67 Confers Enhanced Multi-Abiotic Stress Tolerances in <i>Arabidopsis</i> by Xinguo Mao (233950)

“…Four replications were performed, and values are means ± SE. Fig. S4, A rapid decrease, slow increase and slow decrease pattern in chlorophyll content was identified Arabidopsis after exposure to high salinity. …”