Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling-7 by Troels Schepeler (79446)

“…Exogenous dnTCF1 proteins are induced as early as 3 hr after induction, and c-MYC protein levels decrease in parallel. Real time RT-PCR shows that CLU34 and p21mRNA levels do not increase until 12 hr after induction. c-MYC mRNA levels decrease 6 hr after induction. …”

Investigating the effect of postharvest conditions on the microbial quality and physicochemical characteristics of bee pollen by Vasilios Liolios (12182977)

“…When fresh pollen was stored at 4 °C, over a six-month period, the MTVC & ENT counts were out of limits, and changes were observed in colour, total lipid content (32.18% decrease), and fatty acid composition (31.68% for C18:2 and 21.56% for C18:3 reduction, 31.5% increase for C18:0). …”

Time traces of the end-to-end length of DNA. by Rifka Vlijm (133750)

“…They both show a very similar stepping behaviour. The fitted steps of several protein flushes of 5 different molecules are analized with the step-finder algorithm and the result is shown in the histogram. …”

Regional ventilation and respiratory system compliance. by Günther Zick (20626)

“…<p>Ventrodorsal profiles of regional tidal volume (V_T) (A), regional respiratory system compliance (C_RS) (C) and differences in regional V_T (ΔV_T) (B) and regional C_RS (ΔC_RS) (D) with respect to baseline (mean values ±SD in 10 animals). …”

Pyrvinium inhibits Wnt signaling. by Sarika Saraswati (236578)

“…(<b>B</b>) Pyrvinium (100 nM) decreases transcript levels of endogenous Wnt target genes Myc, Dkk-1, and Axin2 as assessed by real-time PCR. …”

Over-expression of NF-Y or USF increases <i>Miwi</i>-luciferase activity. by Yu Hou (164094)

“…GC-1 or COS7 cells were transfected with 0.2 µg pGL3-5M4 and 0.2 µg NF-Y expression plasmids (pCX-NFYa, pCX-NFYb, pCX-NFYc) as indicated. b), The mutated CCAAT box construct pGL3-5M4-Cmut (0.2 µg) contransfected with NF-Y expression plasmids (pCX-NFYa, pCX-NFYb, pCX-NFYc) as indicated, does not increase the <i>Miwi</i>-luciferase activity. c), The dominant negative NF-Ya expression plasmid NF-YAM29 (0.1 µg, 0.2 µg, 0.3 µg) was cotransfected with 0.2 µg pGL3-5M4, which inhibits <i>Miwi</i>-luciferase activity. d), Over-expression of USF1/2 upregulates <i>Miwi</i>-luciferase activity. pGL3-5M4 (0.2 µg) was cotransfected with 0.2 µg expression plasmids (pCX-USF1 and/or pCX-USF2) into GC-1 or COS7 cells. e), E2 box mutant pGL3-5M4-E2mut (0.2 µg) was cotransfected with 0.2 µg USF1 and/or USF2 expression plasmids (pCX-USF1 and/or pCX-USF2), indicating no increase in luciferase activity. f), The dominant negative USF expression plasmid A-USF (0.1 µg, 0.2 µg, 0.3 µg) was cotransfected with 0.2 µg pGL3-5M4, which inhibits <i>Miwi</i>-luciferase activity. pGL3-basic was employed as a negative control. pRT-TK served as an inner control for transfection efficiency. …”

The expression of BDNF is reduced in the cerebral cortex and striatum of ceruloplasmin-deficient mice. by Sarah J. Texel (343929)

“…<p><b>A.</b> RT-PCR measures of the 4 BDNF transcripts show a decrease in BDNF transcripts 1, 2 and 4 in the cortex of the CpKO mouse (*p<0.04, n = 5). …”

TNKSi induces the binding of TNKSs to axin. by Estefania Martino-Echarri (2548186)

“…Quantification of axin-bound TNKS-1, TNKS-2 and β-catenin band intensities from two separate experiments are shown (mean ± SD). …”

Effects of Gu-4 on survival and expression profiles of TNF-α and IL-10 in septic mice. by TingTing Yan (5652595)

“…<p>A: Survival of septic mice induced by LPS stimulation (37.5 mg/kg <i>i.p.…”

Low-dose curcumin treatment increases OEC proliferation. by Johana Tello Velasquez (652843)

“…<p>(A–D). Increased proliferation of OECs was observed after treatment with 0.5 µM curcumin (B) or 0.5 µM curcumin combined with G5 supplement (D); cells appeared to have longer processes and formed a net-like structure. …”

Supplementary Material for: Identification of Responders to Sorafenib in Hepatocellular Carcinoma: Is Tumor Volume Measurement the Way Forward? by Bargellini I. (4144720)

Effect of changes in the amount of positive reinforcement of R and T. by Guillermo E. Delmas (6169820)

“…<p>(<b>A</b>) The rats were pre-trained by pay-off matrix [<i>P</i>_<i>R</i> = 1, <i>P</i>_<i>T</i> = 3, <i>P</i>_<i>P</i> = 4, <i>P</i>_<i>S</i> = 8 and contrast ] (filled dots) and the cooperation was strongly affected by change of temptation payoff, decreasing when T payoff increased and matrix with changed to [<i>R</i> = 1, <i>T</i> = 5, <i>P</i> = 4, <i>S</i> = 8 and contrast ] (open circles). …”

Effect of prolactin on the phosphorylation of Ca-dependent PKC isoforms by Silvia Taffetani (77822)

“…</p><p></p> Immunoblots for PKC-α, PKC-β-I, PKC-β-II and PKC-γ in normal female cholangiocytes stimulated for 90 minutes at 37°C with 0.2% BSA (basal value) or prolactin (100 nM) with 0.2% BSA. …”

Ethanol but not methanol treatment affects the number of functional sensory hair cells in the lateral line. by Phillip M. Uribe (285454)

“…There was a significant decrease (**p<0.01) in the number of double-labeled hair cells at the two highest concentrations of ethanol tested. …”

Kinesin^CaaX localizes near the nucleus and kinetoplast and is enriched in post-mitotic cells. by Erin J. Engelson (198218)

“…(<b>B</b>) DAPI staining and fluorescence microscopy reveals a larger proportion of cells with 2 kinetoplasts and one nucleus (2K1N) and a reduction in 1K1N cells in tetracycline-induced Kinesin^CaaX<i>T. brucei</i> cells compared with non-induced cells, with the effect becoming prominent at 48 hours (<b>C</b>) The mean and SD of 2 experiments at 48 hours. …”

Impact of propofol on survival promoting proteins. by Tanja Karen (586165)

“…There was an effect of propofol treatment in decrease of pAKT levels over time in the thalamus, which was significant after 12 hrs [F(1,28) = 5.6, p = 0.06]. …”

Table 1_Predicting the potential distribution of Corylus heterophylla in China under future climate change using an optimized MaxEnt model.docx by Jingyu Wang (292122)

“…The dominant factors influencing the distribution were identified as Bio16 (Precipitation of wettest quarter, 39.5%), Bio9 (Mean temperature of driest quarter, 22.2%), Alt (Altitude, 16.2%), and Bio3 (Isothermality, 7.1%). …”

Effects of hormone therapy and high-fat diet on microglia in female mice. by Amy Christensen (4062937)

“…<p>Microglia were morphologically classified into three types: (A) Type 1 are highly ramified and were considered non-activated; (B) Type 2 have rod-shaped cell bodies and only short, mostly unbranched processes; (C) Type 3 have round cell bodies with no processes or only filopodia. …”

Disruption of EAE pathogenesis by B cell depletion. by Nancy L. Monson (121113)

“…Disease course of WTLM and hCD20Tg mice, EAE onset and severity was monitored using a 5-point scale. Shown are the mean clinical score +/− SEM. …”

Floral organ numbers in “Malmaison” and “St Anne's”. by Annick Dubois (19875)

“…The two rose varieties differ in two floral characters: organ identity reversions from petals in “Malmaison” to stamens in “St Anne's” and an overall decrease in total organ number. …”