Propofol inhibits burn injury-induced hyperpermeability through an apoptotic signal pathway in microvascular endothelial cells by K.Y. Tian (6515141)

“…Compared with a sham treatment group, intrinsic apoptotic signaling activation - indicated by Bax overexpression, Bcl-2 downregulation, Δψm reduction, decreased intracellular ATP level, increased cytosolic cytochrome C and smac, and caspase-3 activation - was observed in the vehicle group. …”

Experimental and simulated disruptions of Hedgehog signaling. by Sabine Schilling (225626)

“…In both experiments (C) and simulation (D), <i>smo⁻</i> clones in the anterior compartment show a highly significant trending for decreasing roundness away from the boundary. …”

GRP/GRP-R regulated N-myc expression. by Jingbo Qiao (382330)

“…<p>(<b>A</b>) N-myc and AKT2 expression in BE(2)-C/shCON and BE(2)-C/shGRP-R cells by Western blotting. …”

Trajectory classifier robustness across neural population sizes during SCT. by Jorge Gámez (6565157)

“…<p><b>A</b>. SVM classifier performance (mean ± SD of percent of correct classifications) for target interval (five instructed intervals) during the SCT task based on the neural trajectory computed from different population sizes. …”

Data_Sheet_1_Human neural network activity reacts to gravity changes in vitro.pdf by Johannes Striebel (13901919)

“…During the microgravity phase, the mean action potential frequency across the neural networks was significantly enhanced, whereas different subgroups of neurons showed distinct behaviors, such as increased or decreased firing activity. …”

Image_1_Knockdown of LMTK3 in the Endometrioid Adenocarcinoma Cell Line Ishikawa: Inhibition of Growth and Estrogen Receptor α.tif by Guiyang Cai (11584636)

“…There was a positive correlation between the mRNA expression levels of LMTK3 and ESR1 (Spearman: P=2.011e-5, R=0.13; Pearson: P=7.18e-8, R=0.17). …”

Data_Sheet_1_Extreme Low-Temperature Stress Affects Nutritional Quality of Amino Acids in Rice.docx by Min Kang (287002)

“…<p>Global climate change has increased the frequency of extreme climate events, and their effects on the nutritional quality, especially on amino acids in rice, have not been quantified. The data from a 3-year low temperature stress (LTS) experiment including two rice varieties (Huaidao 5 and Nanjing 46), seven minimum/maximum temperature levels (one optimal 21/27°C and six LTS levels from 17/23 to 6/12°C), and three LTS durations (3, 6, and 9 days) after flowering, revealed significant interactive effects of LTS at different stages, durations, and temperature levels on the content and accumulation of amino acids. …”

Table_1_The Effect of Early Life Exposure to Triclosan on Thyroid Follicles and Hormone Levels in Zebrafish.docx by Ning Tang (138218)

“…Exposure to TCS from 3 to 300 ng/mL reduced the thyroid hormones production. The mean TT₃ and FT₃ levels of zebrafish decreased in 300 ng/mL TCS at 14 dpf (300 ng/mL TCS vs. control : TT₃ , 0.19 ± 0.08 vs. 0.39 ± 0.06; FT₃, 19.21 ± 3.13 vs. 28.53 ± 1.98 pg/mg), and the FT₄ decreased at 120 dpf ( 0.09 ± 0.04 vs. 0.20 ± 0.14 pg/mg). …”

The AGO1 N-terminal extension is required for miRNA accumulation. by Ye Xu (29869)

“…Red and blue dots denote miRNAs or miRNA*s with significantly increased and decreased abundance (average RPM > 2, fold change > 1.5 and adjust <i>P</i> value < 0.01), respectively. …”

Model for the Differentiation of the HMS. by Caleb Gonzalez (270214)

“…<p>(A) We suggest that differentiation of the HMS results from the convergence of three events: acquisition of a DNA double-strand break (DSB) or double-strand end (DSE, one end of a DSB); induction of the SOS DNA-damage response; and induction of the RpoS general stress-response (modified from Figure 5 in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000208#pgen.1000208-Galhardo1" target="_blank">[2]</a>). …”

Comparison between theories and simulations of the stochastic model (related to Fig 3). by Xiangrui Ji (16705908)

“…<p>(A) 〈<i>V</i>_<i>b</i>〉 decreases with <i>K</i>_<i>n</i>,inh, and the CV of <i>V</i>_<i>b</i> increases with <i>K</i>_<i>n</i>,inh. …”

Scheme of the kinetic model. by Maria José Ramírez-Bajo (515922)

“…Limiting rates for HK (<i>V_HK</i>) and PFK (<i>V_PFK</i>) decrease at increasing values for Hg²⁺ and Cd²⁺ following <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0080018#pone.0080018.e001" target="_blank">equations (1)</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0080018#pone.0080018.e002" target="_blank">(2)</a>, respectively for Hg²⁺ and Cd²⁺, with <i>V⁰_HK</i> = 63.0 nmol mg prot⁻¹ min⁻¹ and <i>V⁰_PFK</i> = 434 nmol mg prot⁻¹ min⁻¹.…”

BMA parameter changes across neurofeedback training runs. by Frank Scharnowski (532077)

“…The learners also showed a significantly decreasing effect of up-regulation on the bottom-up connection from the visual ROI to the cSPL (up_V-SPL). …”

Parametrization of the shapes of linear filter sets. by Vincent Jacob (4637236)

“…(A) Individual short-term linear filters for 209 ORNs sorted by decreasing parameter <i>φ</i> (see (E)). …”

Data Sheet 1_Safety assessment of tolvaptan: real-world adverse event analysis using the FAERS database.docx by Peiyang Cao (10808613)

“…Notably, strong ADE signals were detected for decreased urine osmolality [n = 5, ROR 149.74, PRR 149.7, IC (Information Component) 7.13, EBGM (Empirical Bayes Geometric Mean) 139.79], osmotic demyelination syndrome (n = 38, ROR 128.47, PRR 128.25, IC 6.92, EBGM 120.91), and pulmonary-related tumors such as bronchial metastatic carcinoma, bronchial carcinoma, metastatic small cell lung carcinoma, and small cell lung carcinoma. …”

Physiological levels of human MIC-1/GDF15 reduce weight and food intake in mice. by Vicky Wang-Wei Tsai (310159)

“…Food intake, body weight and serum levels of human MIC-1/GDF15 were measured on day 5 of infusion. (A) MIC-1/GDF15-treated MIC-1^−/− mice had an average serum MIC-1/GDF15 level of 643±67 pg/ml and weighed 95.86±0.77% of their starting body weight whilst vehicle-treated mice weighed 102.3±0.75% of their starting weight (<i>n</i> = 6/group, <i>p</i><0.01 <i>unpaired t-test</i>). …”

Cytokines shape the unique functional phenotype of synovial monocytes. by Bo Ruem Yoon (646404)

“…<p>PBMC or purified monocytes derived from HC were stimulated for 18 hours with the indicated TLR agonists or cytokines and expression of CD14 and CD16 were analyzed by flow cytometry. (<b>A</b>) Representative flow cytometric analysis of change in CD16 expression on monocytes (left) and bar graph showing the decreased frequency of the CD14⁺CD16⁺ monocytes after stimulation with LPS (10 ng/ml) or zymosan (Zym; 10 ug/ml) (right; n = 5). …”

Functional Trait Strategies of Trees in Dry and Wet Tropical Forests Are Similar but Differ in Their Consequences for Succession by Madelon Lohbeck (731258)

“…We evaluated whether multivariate plant strategies changed during succession, by calculating a ‘Community-Weighted Mean’ plant strategy, based on species scores on the first two PCA-axes. …”

Lung bacterial burden as measured by colony forming units (CFU) over time. by S. Anisah Alyahya (742654)

“…At all time points measured, no significant statistical differences were noted between the TV Ad35+ group, the vector control group, NC-V, and the main control group, NC-T4 (ANOVA) Boosting with Ad26-TBS at week 16 did not result in decreased bacterial burden by week 28 compared to all other groups in the study (p = 0.14, ANOVA)</p>…”

Chronic MIF exposure induces mesenchymal epithelial transition. by Katherine T. Morris (286978)