Experimental Gastric Carcinogenesis in <i>Cebus apella</i> Nonhuman Primates by Joana de Fátima Ferreira Borges da Costa (212759)

“…The last surviving MNU-treated animal developed intestinal-type gastric adenocarcinoma observed by endoscopy on the 940^th day. The level of C-reactive protein level and homocysteine concentration increased while the level of folic acid decreased with the presence of tumors in ACP03-inoculated animals and MNU treatment. …”

Gemcitabine and ATR inhibitor synergism and effects on the cell cycle and DNA damage in CH22 and U-CH17PII (Batch 2) by Chordoma Foundation (4391989)

“…(<b>C.</b> and <b>F.</b>) γ-H2AX intensity normalized to DNA content is shown for CH22 and U-CH17PII for each treatment regime. …”

Psychophysical and psychophysiological data of the test group (<i>N₁</i> = 16) and the control group (<i>N₂</i> = 16) during pre-conditioning HNCS (BL2) and p... by Raymonde Scheuren (523093)

“…<p>Pre-conditioning BL2 values were contrasted to pre-conditioning BL1 values (1 trial for each BL). …”

Image_1_Long Noncoding RNA X-Inactive-Specific Transcript Promotes the Secretion of Inflammatory Cytokines in LPS Stimulated Astrocyte Cell Via Sponging miR-29c-3p and Regulating N... by Mengqi Zhang (1580830)

“…</p>Results<p>XIST expression and NFAT5 protein level was increased, whereas miR-29c-3p expression was decreased in the epilepsy rat model and LPS-treated CTX-TNA2 cells. …”

Adverse event list. by Stefan Halbherr (21353882)

“…</p><p>Non-motor symptoms of PD, motor parkinsonian signs off medication, and quality of life improved significantly during the treatment phase, including the MDS-UPDRS total score (mean decrease −11.09; 95% Confidence Interval [CI]; −18, −4.1; <i>p</i> = 0.006), the Parkinson’s disease Questionnaire-39 (PDQ-39) summary index (mean decrease −2.91; 95% CI; −4.4, −1.4; <i>p</i> = 0.005), and the Non-Motor Symptoms Questionnaire (NMS-Quest) (mean decrease −4.27; 95% CI; −6.5, −2.1; <i>p</i> = 0.009). …”

Patient characteristics. by Stefan Halbherr (21353882)

“…</p><p>Non-motor symptoms of PD, motor parkinsonian signs off medication, and quality of life improved significantly during the treatment phase, including the MDS-UPDRS total score (mean decrease −11.09; 95% Confidence Interval [CI]; −18, −4.1; <i>p</i> = 0.006), the Parkinson’s disease Questionnaire-39 (PDQ-39) summary index (mean decrease −2.91; 95% CI; −4.4, −1.4; <i>p</i> = 0.005), and the Non-Motor Symptoms Questionnaire (NMS-Quest) (mean decrease −4.27; 95% CI; −6.5, −2.1; <i>p</i> = 0.009). …”

Antibiotics activates autophagy. by Yanhai Feng (6852881)

“…Antibiotics increased the expressions of Atg5 and ratio of LC3-II/LC3-I, but decreased P62 expression. …”

Table_2_Human Chondrocyte Activation by Toxins From Premolis semirufa, an Amazon Rainforest Moth Caterpillar: Identifying an Osteoarthritis Signature.XLS by Isadora M. Villas-Boas (9394205)

“…In the supernatant of cell cultures treated with the extract, we observed increased IL-6, IL-8, MCP-1, prostaglandin E2, metalloproteinases (MMP-1, MMP-2, MMP-3 and MMP-13), and complement system components (C3, C4, and C5). …”

Data_Sheet_2_Drivers of Natural Variation in Water-Use Efficiency Under Fluctuating Light Are Promising Targets for Improvement in Sorghum.xlsx by Charles P. Pignon (9019526)

“…<p>Improving leaf intrinsic water-use efficiency (iWUE), the ratio of photosynthetic CO₂ assimilation to stomatal conductance, could decrease crop freshwater consumption. iWUE has primarily been studied under steady-state light, but light in crop stands rapidly fluctuates. …”

Image_2_Human Chondrocyte Activation by Toxins From Premolis semirufa, an Amazon Rainforest Moth Caterpillar: Identifying an Osteoarthritis Signature.TIF by Isadora M. Villas-Boas (9394205)

“…In the supernatant of cell cultures treated with the extract, we observed increased IL-6, IL-8, MCP-1, prostaglandin E2, metalloproteinases (MMP-1, MMP-2, MMP-3 and MMP-13), and complement system components (C3, C4, and C5). …”

Image2_DNA methylation-mediated FGFR1 silencing enhances NF-κB signaling: implications for asthma pathogenesis.TIF by Minglu Meng (19725085)

“…</p>Methods<p>RT-qPCR was utilized to assess FGFR1 mRNA levels in the serum of asthma patients and BEAS-2B, HBEpiC, and PCS-301-011 cells. CCK8 assays were conducted to evaluate the impact of FGFR1 overexpression on the proliferation of BEAS-2B, PCS-301-011, and HBEpiC cells. …”

Purification and characterization of the deletion mutants. by Amanda Jack (11547638)

“…UV absorbance of WT N under the same experimental conditions is shown in a dashed red curve for comparison. <b>(C)</b> EMSA gels using no RNA, 10 nM 0–5 kb viral RNA, or 50 ng/μL polyC RNA and decreasing concentration of the ΔR2 mutant. …”

Effect of preeclampsia (PE), preeclampsia-like conditions and 1,25(OH)₂ vitamin D₃ on HUVEC migration. by Lars Brodowski (570966)

“…Scale bar represents 750 μm. (C) Effect of villous explant conditioned medium (2% O₂, 8% O₂, 21% O₂ CM) and 1,25(OH)₂ vitamin D₃ on HUVEC migration with a reduction at 2% O₂. …”

Gel filtration and EMSA analysis of the WT N protein purified from HEK293S GNTI- cells. by Amanda Jack (11547638)

DataSheet_1_Case Report: Novel Compound Heterozygous RNASEH2B Mutations Cause Aicardi–Goutières Syndrome.docx by Jessica Garau (10698978)

“…Lower protein levels of RNase H2A have been observed in all the members of the family as well, whereas a deep depletion of RNase H2C has only been identified in the affected child. …”

The PI3K/AKT/mTOR pathway was involved in regulating FASN expression in ER+/HER2+ breast cancer cells. by Chen Yan (478322)

“…The decrease in the transcriptional activity of the FASN promoter was most pronounced in MCF-7/HER2 cells (MCF-7/HER2 86.09%; SKBR3, 80.27%; and MCF-7, 69.05%). …”

Table2_Phosphorus Cycle and Primary Productivity Changes in the Tethys Ocean During the Permian-Triassic Transition: Starving Marine Ecosystems.XLSX by Johann Müller (12218528)

“…We suggest that the productivity collapse started in the upper C. yini conodont Zone, approximately 30 ka prior to the main marine extinction interval. …”

Targeted Ablation of <i>Crb1</i> and <i>Crb2</i> in Retinal Progenitor Cells Mimics Leber Congenital Amaurosis by Lucie P. Pellissier (243199)

Inflammation markers, cytokines and pro-inflammatory M1/anti-inflammatory macrophage M2 profile markers in the kidney post IRI. by Marya Morevati (5593805)

“…These results indicate together with induction of activin A (as shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0252554#pone.0252554.g008" target="_blank">Fig 8</a>), which is involved in M1 polarization state and the decrease in <i>BMP7</i>, which is involved in the M2 polarization state, that the classically activated macrophage M1 is pre-dominant in IRI and independent of NAD+ boosting. …”

Influence of <i>SRPN7</i> and <i>CLIPC2</i> silencing on mosquito resistance to bacterial challenge and midgut microbiota proliferation. by Benjamin J. Blumberg (453329)

“…Statistical significance was determined using Kaplan-Meier survival analysis with a log-rank test using Bonferonni's correction for multiple comparisons (significance  = p<0.025. (C) RNAi-mediated gene silencing of <i>SRPN7</i> or <i>CLIP2</i> resulted in a significant decrease (p<0.05) in the colony forming units (CFU) of cultivable midgut bacteria when compared to <i>dsGFP</i>-injected control mosquito midguts. …”