Silencing of PINK1 expression or exposing to MPP⁺ led to increase in the level of exogenous BAG5 in PC12 cells. by Xuejing Wang (514409)

“…Suppression of PINK1 expression by PINK1-targeting siRNAs significantly enhanced exogenous BAG5 levels, and decrease of exogenous PINK1 induced by neurotoxin MPP⁺ also resulted in a significant increase of exogenous BAG5. …”

Table_1_Changes in Vitamin A Levels and the Effect of Early Vitamin A Supplementation on Vitamin A Levels in Infants Throughout the First 6 Months of Life: A Prospective Cohort Stu... by Huan Liu (281351)

“…From birth to 6 months, the percentage of infants with a VA level <0.70 μmol/L decreased from 88.6 to 19.5%. …”

The crucial role of Activin A on the formation of primordial germ cell-like cells from skin-derived stem cells in vitro by Rui Sun (177521)

“…Moreover, mice treated with ActA at 100 ng/kg body weight from embryonic day (E) 5.5–12.5 led to more PGCs formation. …”

Data_Sheet_1_Whole-Genome Sequencing Reveals Exonic Variation of ASIC5 Gene Results in Recurrent Pregnancy Loss.PDF by Nourah H. Al Qahtani (11208033)

“…WGS of dead fetus identifies a novel homozygous exonic variation (NM_017419.3:c.680G>T) in ASIC5 (acid-sensing ion channel subunit family member 5) gene; the parents are heterozygous. …”

Vitamin D treatment of peripheral blood mononuclear cells modulated immune activation and reduced susceptibility to HIV-1 infection of CD4⁺ T lymphocytes by Sandra M. Gonzalez (7423307)

“…In this regard, it has been proposed that immunomodulatory compounds capable of modulating immune activation, such as Vitamin D (VitD) may reduce HIV-1 transmission and might be used as a safe and cost-effective strategy for prevention. …”

Data_Sheet_1_A Prospective Multicenter Trial to Evaluate Urinary Metabolomics for Non-invasive Detection of Renal Allograft Rejection (PARASOL): Study Protocol and Patient Recruitm... by Miriam C. Banas (2827475)

“…Most of the samples (51.1%) were collected within the first 6 months after transplantation, 48.0% were protocol biopsies, followed by event-driven (43.6%), and follow-up biopsies (8.5%). Over time the proportion of biopsies classified into the categories Banff 4 (T-cell-mediated rejection [TCMR]) and Banff 1 (normal tissue) decreased whereas Banff 2 (antibody-mediated rejection [ABMR]) and Banff 5I (mild interstitial fibrosis and tubular atrophy) increased to 84.2 and 74.5%, respectively, after 4 years post transplantation. …”

PrP2 is expressed in the primordium. by Sylvaine Huc-Brandt (667335)

“…Quantification analysis using pixel intensity measurement with ImageJ software, within the primordium areas, reveals a significant decrease of PrP2 expression level in <i>Prp2</i>-MO. a.u.: arbitrary unit of pixel intensity, area: primordium anlage (*** p<0.001, Mann-Whitney test, n = 10).…”

ROS is the major player in regulating altered autophagy and lifespan in <i>sin-3</i> mutants of <i>C. elegans</i> by Meenakshi Sharma (107997)

“…In this study using a <i>Caenorhabditis elegans sin-3(tm1279);him-5(e1490)</i> strain, we demonstrate that under <i>in vivo</i> conditions SIN-3 differentially modulates autophagy and lifespan. …”

Effect of 2-DG on T-cell populations. by Saurabh Singh (10870)

“…<p>(A) 2-DG had a differential and dose dependent effect on CD4⁺ (decrease) and CD8⁺ (increase) T-cell subpopulations reflected in reduced (B) CD4⁺/CD8⁺ ratios. …”

Detection of ETs using SYTOX green. by Mahshid Vafajoo (21144147)

Locomotor activity at different light intensities. by Stanislav Lazopulo (821274)

Global 16S metagenomics profiling. by Francesco Favero (236209)

Ca²⁺ sensitivity of the contractile apparatus and maximum Ca²⁺-activated force. by Thomas J. Harvey (800460)

“…(C: 8.98 mN/mm² ± 0.18 vs NR: 3.38 ± 0.27; <i>F</i> (1,8) = 2.966, P>0.05). …”

<b>Seizure-induced changes in cytokine expression and dysregulation of plasminogen activation and IGF systems following kainic acid administration in rats</b> by Elena Suleymanova (22195777)

“…We also observed disruption of the IGF system, characterized by decreased IGFBP-5 protein levels in the hippocampus and downregulation of <i>Igfbp5</i> mRNA in both hippocampus and cortex. …”

AD progression drives global perturbations in the microbiota. by Francesco Favero (236209)

Requirement of two polybasic clusters in the PIP_n-regulated P2X4 subtype. by Louis-Philippe Bernier (316296)

“…B) The GST construct containing the P2X4 C-terminal domain C360-V375 binds to several PIP_n including PIP₂ and PIP₃. …”

The role of intracellular Ca²⁺ in the impedance response to β₂AR stimulation. by Wayne Stallaert (192209)

“…(<b>C–F</b>) Pre-treatment with 2-APB or BAPTA-AM also leads to an inhibition of the rapid ascending phase and a decrease in the maximum impedance responses of ligands from Groups I to IV: ISO (C), salbutamol (SALB, D), alprenolol (ALP, E) and propranolol (PRO, F), respectively (1 µM each). …”

Sequence conservation, alignments and homology modeling of recombinant Rrd1. by Mohd Kashif (769104)

<i>pqn-59</i> depletion corrects the reduction of mature <i>lin-4</i> and <i>let-7</i> miRNA levels observed in <i>alg-1(0)</i> mutants and has little effect on the expression of c... by Colleen Carlston (11740725)

“…<b>(B)</b> Taqman assays as outlined in panel A performed on young adult-staged <i>lin-31(n1053)</i> and <i>lin-31(n1053); alg-1(ma192)</i> animals subjected to control or <i>pqn-59</i> dsRNAs. <b>(C)</b> In the <i>eri-1(ok2683)</i> RNAi hypersensitive strain <i>pqn-59</i> depletion decreases PQN-59 to 12% of its abundance in control <i>eri-1(ok2683)</i> animals. …”

Immunofluorescence expression of astrocyte and neuronal cells in brain tissues following the injury. by Ghaith A. Bahader (21387572)

“…(C) Analysis of NeuN+ positive cells in the peri-lesional areas showed a significant decrease in the neuronal cell numbers in the TBI/H groups, as compared to the Sham + saline group (* p < 0.05); n = 5–6 per experimental group. …”