Hypothetical model defines early stages of AD by temporal pattern of CSF protein biomarker levels. by Richard J. Perrin (224124)

“…CSF Aβ42 appears to decrease further as cognition declines from normal (Clinical Dementia Rating [<b>CDR</b>] <b>0</b>) to very mild cognitive impairment (<b>MCI, CDR 0.5</b>) to mild dementia (<b>CDR 1</b>). …”

Bacterial model fit to the data of Ref. [21]. by Florian G. Pflug (5130623)

“…<b>(c)</b> Average instantaneous speed <i>v</i>(<i>τ</i>) = <i>v</i>₀<i>h</i>(<i>τ</i>) as a function of the fraction <i>τ</i>/<i>τ</i>₂ of the doubling time <i>τ</i>₂ = log(2)/Λ. …”

Inhibition controls levels of pattern separation in granule cells through different neural codes. by Antoine D. Madar (6619286)

“…Red curves (after gzn) are all shifted to the left of their black counterparts (before gzn), showing a decrease in pattern separation at all time scales. …”

Figure 4, supplementary figure 6 by Kristen Pleil (11084931)

“…</b>a) Systemic E2 synthesis inhibition in high ovarian E2 mice using the aromatase inhibitor letrozole (LET, 10 mg/kg). b) Effects of LET administration on EtOH consumption (N’s = 13 saline VEH, 19 LET). c) Effects of LET administration on elevated plus maze (EPM) % time spent in the open arms (left) or distance traveled (right; N’s = 15 VEH, 14 LET). d) Intra-BNST infusion of LET (1 μg in 200 nl/side) in high E2 status females. e) Effects of intra-BNST LET on EtOH consumption (N’s = 7 VEH, 6 LET). f) Intra-BNST infusion of E2 (20 pg in 200 nl/side) or membrane-impermeable E2 (mE2, 55 pg in 200 nl/side) in low E2 status females. g) Effects of intra-BNST E2 on EtOH consumption (N’s = 8 VEH, 7 E2). h) Effects of intra-BNST mE2 on EtOH consumption (N’s = 12 VEH, 11 mE2). i) Effects of intra-BNST E2 on EPM % time spent in the open arms (left) or distance traveled (right; N’s = 7 VEH, 8 E2). j) Effects of bath application of E2/mE2 on excitatory synaptic transmission in BNSTCRF neurons during slice electrophysiology recordings in low ovarian E2 status female CRF-CrexAi9 reporters. k) Spontaneous excitatory postsynaptic currents (sEPSCs) maximum delta from % baseline during E2/mE2 wash on (E2 nM: 0.01: N = 2, 2 cells; 1: N = 4, 4 cells; 10: N = 5, 7 cells; 100: N = 4, 4 cells; 1000: N = 3, 5 cells; 100 nM mE2: N = 3, 6 cells; l and m are the same cells). l) Time course of BNSTCRF neurons that displayed increase/decrease/no change in sEPSC frequency and amplitude (m) % change from baseline during E2 application and proportion of responding categories (pie charts). …”

Image_1_Radiation Induces Valvular Interstitial Cell Calcific Response in an in vitro Model of Calcific Aortic Valve Disease.tif by Manon Meerman (11353515)

Inoculation of Tg9949 mice with PrP amyloid, but not other PrP conformations, results in the generation of prions. by David W. Colby (254454)

“…Brain samples from mice inoculated with non-amyloid PrP conformations did not show activity in the ASA (<b>C</b>). Activity in the ASA was detected by an increase in ThT fluorescence (<b>B and top of panel C</b>) and by a decrease in the mean lag phase for PrP amyloid formation (<b>bottom of panel C</b>). …”

Image_1_Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584.tif by Pahul Singh (14781409)

“…Ozone and LPS exposure induced lung neutrophil and eosinophil recruitment as measured by respective peroxidase (MPO and EPX) assays, systemic leukopenia, increased levels of lung vascular neutrophil regulatory chemokines such as CXCL5, SDF-1, CXCL13 and a decrease in immune-regulatory chemokines such as BAL IL-10 and CCL27. …”

Image_3_Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584.tif by Pahul Singh (14781409)

“…Ozone and LPS exposure induced lung neutrophil and eosinophil recruitment as measured by respective peroxidase (MPO and EPX) assays, systemic leukopenia, increased levels of lung vascular neutrophil regulatory chemokines such as CXCL5, SDF-1, CXCL13 and a decrease in immune-regulatory chemokines such as BAL IL-10 and CCL27. …”

Post-treatment controllers differ from HIV controllers in terms of HLA class I profile, frequency and quality of the CD8+ T cell response and activation levels of CD8+ T cells. by Asier Sáez-Cirión (3141075)

“…The statistical analyses are shown in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003211#ppat.1003211.s006" target="_blank">Table S2</a>. …”

Behavioral data. by Charmaine Y. Pietersen (37545)

“…FC+Ket), reducing freezing duration (p = 0.0213; C) and frequency (p = 0.0002; d). Haloperidol (p = 0.0040) and LY 379268 (p = 0.0026) were able to partially inhibit this blockade (FC+Ket+Halo/LY vs. …”

Table1_Evidence of survival bias in the association between APOE-Є4 and age at ischemic stroke onset.DOCX by Joanna von Berg (8175756)

“…Each copy of the rs429358:T>C allele was associated with a 1.29-year earlier stroke AAO (meta p-value = 2.48 x 10⁻¹¹). …”

Contribution of NKT cells to the immune response and pathogenesis triggered by respiratory viruses by Emma Rey-Jurado (6059621)

“…Here, we evaluated the contribution of NKT cells in both hRSV and hMPV infections. A significant decrease in the number of neutrophils, eosinophils, and CD103⁺DCs infiltrating to the lungs, as well as an increased production of IFN-γ, were observed upon hRSV-infection in CD1d-deficient BALB/c mice, as compared to wild-type control mice. …”

Constructed protein-protein interaction (PPI) networks and conducted analysis. by Junlong Xiong (12701535)

“…(D) A heatmap plotted using the pheatmap R package (version 1.42.2). …”

Shoshonitic pluton and an associated base-metal deposit in the Tarom–Hashtjin metallogenic zone, NW Iran: implication for tectono-magmatic evolution and metallogenic considerations... by M. Afshari (17554673)

“…The calculated stable isotope values of ore–fluid components (δ¹⁸O_water = +3.28‰ to −3.68‰; δ³⁴S_H2S = +5.5‰ to +7.8‰) show that magmatic fluids have played a significant role during mineralisation. …”

Supplementary Material for: Adjustment of Stent Retriever Length to Clot Extent Affects First-Pass Reperfusion in Endovascular Treatment of Acute Ischemic Stroke by Styczen H. (8979680)

Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection by Lewis H Kuller (29644)

“…Two studies were conducted: (1) a nested case–control study for studying biomarker associations with mortality, and (2) a study to compare DC and VS participants for biomarker changes. …”

Figure 3 - Interspecies Spreading-LC on Moth Wings.ai from The moth specialist spider <i>Cyrtarachne akirai</i> uses prey scales to increase adhesion. by Candido Diaz (1477900)

“…Contaminants decrease adhesive strength by interfering with substrate contact. …”

<i>Lcmt1</i> transcript quantitation in wild-type and <i>Lcmt1^−/−</i> mouse tissues. by Kennen B. MacKay (128896)

“…<p>Panel A: <i>Lcmt1</i> transcript levels from five tissues, measured using primers flanking exons 1 and 2, and exons 2 and 3 as described in the “<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0065967#s2" target="_blank">Methods</a>” section, were normalized to β-2 microglobulin transcript levels measured in the same tissue. …”

Data_Sheet_1_Maternal Mental Health in Late Pregnancy and Longitudinal Changes in Postpartum Serum Vitamin B-12, Homocysteine, and Milk B-12 Concentration Among Brazilian Women.doc... by Mônica Araujo Batalha (13026525)

“…Women with anxiety symptoms at baseline exhibited a decrease in daily postpartum homocysteine concentrations compared to women without anxiety symptoms (β = −0.002, SE = 0.001, p = 0.024).…”

Changing ion concentrations drive the transition of modes in the Purkinje cell model's trimodal pattern of firing. by Michael D. Forrest (292801)

“…<i>B</i>, Membrane potential at a point in the dendrites. The burst mode at the soma corresponds with high threshold Ca²⁺ spiking in the dendrites. …”