Lithiation of 2,4,5,7-Tetrabromo-1,8-bis(dimethylamino)naphthalene: Peculiarities of Directing Groups’ Effects and the Possibility of Polymetalation by Artyom A. Yakubenko (11602733)

“…It was demonstrated that the first exchange occurs in position 4 due to the significant decrease of a steric strain of the molecule. The second exchange takes place in either position 5 or 7 due to the even more negative charge distribution in the naphthalene core. …”

Original data (a, b, c, d) and disproportionality analysis results (ROR & IC). by Mengsi Peng (12882734)

CpG/c stimulated CLL B cells decrease LEF-1 expression and increase PRDM1 expression. by Albert Gutierrez Jr. (342562)

Causal directed acyclic graph (DAG) of the relationship between time-varying exposures for example, HbA1C-SD by Khadije Maajani (10125692)

Subjects:

Green tea polyphenols decrease cell viability and induces apoptosis in LNCaPshV and LNCaPshp53 cells. by Karishma Gupta (293144)

Strain construction and targeted reconstitution. by Fitz Gerald S. Silao (9384713)

Subjects:

Influence of ghrelin treatment (0.5 μg/g BW, twice a day, intraperitoneal (ip.)) on early cytokine response after cecal ligation and puncture (CLP)-induced sepsis. by Daniel Siegl (717509)

Scatterplot of the incidence rate of tuberculosis (TB) in 1990 versus (a) the cumulative mortality rate of COVID-19 and (b) the cumulative incidence rate of COVID-19 on 5 April 202... by Kazuo Inoue (302545)

<i>C</i>. <i>auris</i> induces IL-1Ra in macrophages to decrease the neutrophil function in the skin. by Abishek Balakumar (20189865)

Scatterplot of the mortality rate of tuberculosis (TB) in 1950 versus (a) cumulative mortality rate of COVID-19 and (b) the cumulative incidence rate of COVID-19 on 5 April 2020, a... by Kazuo Inoue (302545)

Preserved NSS at 2 and at 24 hours following ischemia and decreased infarct volume in PAR1 KO mice 24 hours following ischemic stroke. by Efrat Shavit-Stein (3186678)

“…(D) Infarct volume decreases as a function of distance from the ischemic core (slices #5&6). …”

A New Rotane Family:  Synthesis, Structure, Conformation, and Dynamics of [3.4]-, [4.4]-, [5.4]-, and [6.4]Rotane¹ by Lutz Fitjer (2466634)

“…All syntheses are based on bicyclobutylidene (<b>9</b>):  [2+1] cycloaddition of cyclobutylidene yields [3.4]rotane (<b>5</b>) (<b>9</b>−<b>5</b>), [2+2] cycloaddition of trimethyleneketene followed by spiroalkylation of the resulting trispiroketone <b>10</b> yields [4.4]rotane (<b>6</b>) (<b>9</b>−<b>10</b>−<b>13</b>−<b>14</b>−<b>6</b>), homologization of <b>10</b> via β-hydroxy selenides gives access to tetraspiroketone <b>11</b> and pentaspiroketone <b>12</b> (<b>10</b>−<b>15</b>−<b>11</b>−<b>16</b>−<b>12</b>), and further elaboration directed toward a cyclopropylcarbene−cyclobutene rearrangement yields [5.4]rotane (<b>7</b>) and [6.4]rotane (<b>8</b>) [<b>11</b>(<b>12</b>)−<b>18</b>(<b>24</b>)−<b>19</b>(<b>25</b>)−<b>20</b>(<b>26</b>)−<b>21</b>(<b>27</b>)−<b>22</b>(<b>28</b>)−<b>23</b>(<b>29</b>)−<b>7</b>(<b>8</b>)]. …”

A blue-shifted fluorescence donor increases fAP amplitude but exhibits a decreased SNR. A. by Ann E. Fink (312543)

3D spheroids show decreased apoptosis rates after irradiation compared with 2D cultures. by Jana Koch (9936852)

Decrease of cell migration in C2C12 myoblasts by palladin knockdown. by Ngoc-Uyen-Nhi Nguyen (723223)

Serum starvation increases the expression level and prolongs the decay rate of GAS5, and decreases the expression of glucocorticoid-responsive genes. by Hidenori Tani (169942)

Self-reported change in diet, physical activity and medication taking compared to pre-COVID-19 in relation to trajectories of HbA1c in people with diabetes (N = 4,925). by Martin Gillies Banke Rasmussen (10227291)

Subjects:

The Hh signaling pathway effectors are decreased in E14.5 <i>Fuz^−/−</i> mouse embryos. by Zichao Zhang (344301)

“…<b>C</b>) Immunofluorescence of Gli2 in sagittal sections of E14.5 <i>Fuz^+/−</i> heterozygous embryos. …”

Pharmacologic blockade of 5LO modulates tau metabolism, ameliorates synaptic integrity and decreases neuroinflammation in the 3×Tg mice. by Jin Chu (358006)

PGRN-deficient CD4+CD25+ Treg decreased the suppressive capacity to Teff proliferation. by Fanhua Wei (659805)