Uridine 5′-Triphosphate Promotes <i>In Vitro</i> Schwannoma Cell Migration through Matrix Metalloproteinase-2 Activation by Aloa Lamarca (573839)

“…Interestingly, MAPK phosphorylation evoked by UTP exhibited a biphasic pattern, with an early transient phosphorylation 5 min after treatment, and a late and sustained phosphorylation that appeared at 6 h and lasted up to 24 h. …”

ATF1 regulates GC-2 cell apoptosis and changes the bcl-2/bax ratio. by Xiaoxuan Liang (172307)

“…(D) GC-2 cell apoptosis analysis by Annexin V/Propidium Iodide staining after ATF1 knockdown or dual-inhibition of ATF1 and miR-34c. …”

Image_1_MicroRNA-182-5p Attenuates Asthmatic Airway Inflammation by Targeting NOX4.tif by Zhiguang Wang (1751590)

“…MiRNA Microarray Analysis was performed to analyze the differentially expressed miRNAs in the asthma model. We found that the expression of miRNA-182-5p was significantly decreased in OVA-induced asthma. …”

Table_5_Global, regional, and national incidence and mortality of neonatal sepsis and other neonatal infections, 1990–2019.DOCX by Jie Li (15030)

“…The ASDRs of all 5 SDI regions generally showed a downward trend. …”

<b>Data for opposing effects</b><b> of maize straw and its biochar on soil N</b>_{<strong>2</strong>}<b>O emissions</b><b> </b><b>by mediating microbial nitrification and d... by MOULIANG XIAO (21266015)

“…However, biochar addition (5 t C ha⁻¹) reduced available N, i.e., 11.1–13.9% for NH₄⁺, 11.0–14.8% for NO₃⁻ and 13.8–16.6% WSON, and decreased the abundances of nitrification/denitrification genes (39.0–44.6% for AOB <i>amoA</i>, 29.5–35.5% for <i>nirK</i>, 24.4–31.8% for <i>nirS</i>) and associated genera <i>Nitrosospira</i>, <i>Mesorhizobium</i>, <i>Bradyrhizobium</i>, <i>Rhizobium</i>, <i>Pseudomonas</i>, and <i>Cupriavidus</i>. …”

DataSheet5_Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways.ZIP by Mi Zhou (9884)

“…</p><p>Results: Valsartan rescued LPS-reduced cell viability of BEAS-2B cells, improved the pulmonary function, ameliorated pathological lung injury in mice with ALI, ameliorated LPS-induced neutrophil recruitment in BALF and lung tissue of mice, attenuated oxidative stress by increasing the level of SOD and decreasing that of MDA and GSSG, inhibited LPS-induced MUC5AC overproduction, decreased the LPS-induced increase in expression of pro-inflammatory cytokines/chemokines including TNF-α, IL-6, IL-1β, CXCL-1 and CXCL-2, and restored the expression of anti-inflammatory IL-10. …”

Table_5_Sex and age effects on gray matter volume trajectories in young children with prenatal alcohol exposure.XLSX by Madison Long (18336297)

“…Using longitudinal T1-weighted MRI, the present study characterized gray matter volume development in young children with PAE (N = 42, 84 scans, ages 3–8 years) compared to unexposed children (N = 127, 450 scans, ages 2–8.5 years). Overall, we observed altered global and regional gray matter development trajectories in the PAE group, wherein they had attenuated age-related increases and more volume decreases relative to unexposed children. …”

Video5_Revealing the nanometric structural changes in myocardial infarction models by time-lapse intravital imaging.MP4 by Chiung Wen Kuo (2020633)

Table_5_Characterization of Microbiota in Cancerous Lung and the Contralateral Non-Cancerous Lung Within Lung Cancer Patients.XLSX by Minglei Zhuo (283748)

Image_5_Dendritic Cell Maturation Regulates TSPAN7 Function in HIV-1 Transfer to CD4+ T Lymphocytes.tiff by Brieuc P. Perot (8504664)

Fig 3 - by Lukasz Jaroszewski (4284)

Image_1_Fentanyl Inhibits Air Puff-Evoked Sensory Information Processing in Mouse Cerebellar Neurons Recorded in vivo.JPEG by He-Min Yang (9201980)

“…The fentanyl-induced decrease of inhibitory responses in PCs was partially prevented by a PKA inhibitor, H-89.…”

Supplementary material Figure S2 by Alireza Mani (3341171)

“…Abbreviations: haem=haemoglobin, pH = arterial pH, HCO3 = bicarbonate, inr = international normalised ratio, ALT = alanine transaminase, wbc = white blood cell, HR = heart rate, RR = respiratory rate, SpO2 = oxygen saturation. Reference: Morandotti C, Wikner M, Li Q, Ito E, Oyelade T, Tan C, Chen PY, Cawthorn A, Lilaonitkul W, Mani AR. …”

Image_5_Herpes Simplex Virus Type 1 Enhances Expression of the Synaptic Protein Arc for Its Own Benefit.tif by Francisca Acuña-Hinrichsen (6181544)

Image_5_Herpes Simplex Virus Type 1 Enhances Expression of the Synaptic Protein Arc for Its Own Benefit.tif by Francisca Acuña-Hinrichsen (6181544)

Table_1_Smooth muscle contractile responses to bile acids in mouse ileum require TGR5 but not ASBT.DOCX by Diana S. Chang (18433446)

“…Here, we aimed to determine whether these responses are dependent on host sex, the plasma membrane bile acid receptor TGR5, or the apical sodium-dependent bile acid transporter ASBT.…”

Analysis of Jak2 Catalytic Function by Peptide Microarrays: The Role of the JH2 Domain and V617F Mutation by Arturo Sanz (224344)

“…By using for the first time purified recombinant JAK2 proteins and a novel peptide micro-array platform, we have determined initial phosphorylation rates and peptide substrate preference for the recombinant kinase domain (JH1) of JAK2, and two constructs comprising both the kinase and pseudokinase domains (JH1-JH2) of JAK2. …”

Image_5_Apolipoprotein-E deficiency leads to brain network alteration characterized by diffusion MRI and graph theory.JPEG by Margaret Caroline Stapleton (17437713)

“…We hypothesize that ApoE attenuation of LOAD resiliency or vulnerability has a neurodevelopmental origin via changing brain network architecture. …”

Image_5_Novel insights into the intraepithelial spread of extrahepatic cholangiocarcinoma: clinicopathological study of 382 cases on extrahepatic cholangiocarcinoma.tif by Daisuke Nagashima (16842678)

Image5_Laminin 332 expression levels predict clinical outcomes and chemotherapy response in patients with pancreatic adenocarcinoma.JPEG by Bilge Sari (16989051)

“…To explore possible mechanisms, we investigated co-expressed genes, identifying eight hub genes, namely, GJB3, ITGB6, SERPINB5, GPRC5A, PLEK2, TMPRSS4, P2RY2, and TRIM29, which are co-expressed with all three of LAMA3, LAMB3, and LAMC2. …”