Lysine succinylation of <i>Mycobacterium tuberculosis</i> isocitrate lyase (ICL) fine-tunes the microbial resistance to antibiotics by Mingliang Zhou (172233)

“…For the <i>in vitro</i> activity of the purified isocitrate lyase, only K189E mutant showed significantly decreased activity. Crystal structure analysis showed that Lys189 Glu dramatically increased the pKa of Glu188 and decreased the pKa of Lys190, whereas had negligible effect on other residues within 5 Å as well as disruption of the electrostatic interaction between Lys189 and Glu182, which might prevent the closure of the active site loop and cause severe reduction of the enzyme activity. …”

Updating representation of position by betasort on an incorrect trial by Greg Jensen (712648)

“…During explicit feedback, the increases <em>L_E</em> by one, while also increasing <em>U_C</em> by one. This increases the odds of future selections of stimulus <em>C</em>, while decreasing the odds of future selections of stimulus <em>E</em>. …”

Figure 3 from Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer by Ya-Yun Cheng (21751407)

“…<p>MPZL3 knockdown increases EMT gene expression signature which is associated with poor patient outcome. <b>A,</b> Heatmap of EMT signature gene transcripts increased in response to MPZL3 knockdown with two independent shRNAs in OVCAR4 and OVCA433 cells (RNA-seq, <i>z</i>-scores). …”

siRNA for Hes-1 inhibited proliferation of IEC-6 cells. by Guoqing Chen (427510)

“…Data are given as the means ± SDs (<i>n</i> = 5). **<i>p</i><0.01 versus control group. <i>C</i>: Cell count of IEC-6 cells was taken for control group, si-NC, and siRNA for Hes-1 group (magnification×400). …”

Effect of miR-574-3p overexpression on PCa cell proliferation, migration and invasion in vitro and in vivo. by Takeshi Chiyomaru (140914)

“…(C) Over-expression of miR-574-3p significantly inhibits cell migration. …”

Supplementary Material for: Demethylzeylasteral (T-96) Alleviates Allergic Asthma via Inhibiting MAPK/ERK and NF-κB Pathway by Huang J. (3231918)

“…Also, enhanced inflammatory infiltration and mucus hypersecretion were ameliorated in lungs of asthmatic mice following increasing doses of T-96 treatment, accompanied by decreased eosinophils in bronchoalveolar lavage fluid (BALF), IgE and OVA specific-IgE levels in serum and downregulated IL-5 and IL-13 expressions in BALF and lung tissues as well. …”

K_ATP channel activity in pancreatic β-cells from WT and ERβ−/− mice in presence of 1 nM BPA. by Sergi Soriano (184947)

“…<p>A, BPA at 1 nM decreased K_ATP channel activity in pancreatic β-cells from WT mice. …”

Dataset for: Lumped-Parameter Models of the Pulmonary Vasculature during the Progression of Pulmonary Arterial Hypertension by Jesse William Gerringer (4722882)

“…As PAH develops resistances increase nonlinearly (Rd exponentially and R at a slower rate) while compliance linearly decreases. …”

59-year-old male patient with hepatocellular carcinoma, representative case of clinically significant hemoptysis due to penetrating injury of peripheral pulmonary artery and cuttin... by Heekyung Kim (5778257)

“…Hemoptysis persists for 2.5 hours and then spontaneously decreased. <b>E.…”

Study on the properties of alkali-activated ferrochrome slag paste filling materials prepared from multiple industrial solid wastes by Shixing Yang (368885)

“…Moreover, the primary hydration products of FS-CPB were ettringite, C-S-H gels and N-A-S-H gels. The leaching concentrations of total Cr and Cr(VI) satisfied the Class Ι water quality standard limits (≤1.5 mg∙L⁻¹) in GB 8978–1996 and Class III water quality standard limits (≤0.05 mg∙L⁻¹) in GB 14,848-2017, respectively. …”

Figure 6 from p300 KAT Regulates SOX10 Stability and Function in Human Melanoma by Aaron Waddell (19280272)

“…<b>B,</b> Volcano plots of SOX10-repressed genes differentially expressed due to A-485 treatment for IPC-298, CO79, and A375 cells (DEGs defined as FC > |2| and <i>P</i> < 0.05). …”

Accelerated drug action with 3D HD-MEA compared to planar HD-MEA. by Lisa Mapelli (416979)

“…<p>To test the effectiveness of drug perfusion, TTX was applied to acute cerebellar slices. A) Examples of electrical activity maps showing the distribution of active electrodes before (<i><i>top</i></i>) and after TTX application (<i><i>bottom</i></i>) in a slice placed on a 3D chip (color scale bar: 0-300 µV). …”

Hydrogen Sulfide Delays LPS-Induced Preterm Birth in Mice via Anti-Inflammatory Pathways by Weina Liu (549567)

“…Administration of NaHS (i.p.) delayed the onset of labor induced by LPS in a dose-dependent manner. NaHS prevented leukocyte infiltration into intrauterine tissues and inhibited the production of pro-inflammatory cytokines in myometrium and decreased the levels of these cytokines in maternal circulation. …”

Data_Sheet_1_Response of bacterial community composition and co-occurrence network to straw and straw biochar incorporation.docx by Mingcheng Du (13888926)

“…SF (straw with fertilizer) and BF (straw biochar with fertilizer) treatments decreased bacterial community diversity. Co-occurrence networks are more complex in BF, S (straw), and SF treatments, and the number of edge network patterns is increased by 92.5, 40, and 60% at the maturity stage compared with F (fertilizer) treatment, respectively. …”

Necrotizing Enterocolitis, cytokines, and neuroinflammation. by Cuilee Sha (4836888)

“…Created in BioRender.com. Hsieh, H. (2025) <a href="https://BioRender.com/5hy3eg0" target="_blank">https://BioRender.com/5hy3eg0</a>.…”

DataSheet_2_Quantitative Multicomponent T2 Relaxation Showed Greater Sensitivity Than Flair Imaging to Detect Subtle Alterations at the Periphery of Lower Grade Gliomas.docx by Pietro Bontempi (10338872)

“…The first type, observed in three patients, was a reduced extension of the abnormal regions on T2 map with respect to FLAIR images (T2 decrease pattern). …”

DataSheet_1_Quantitative Multicomponent T2 Relaxation Showed Greater Sensitivity Than Flair Imaging to Detect Subtle Alterations at the Periphery of Lower Grade Gliomas.docx by Pietro Bontempi (10338872)

“…The first type, observed in three patients, was a reduced extension of the abnormal regions on T2 map with respect to FLAIR images (T2 decrease pattern). …”

Kinetics of PKH26 and In vitro Spheroid Formation. by Anna Pastò (310643)

“…<p>(A) Cells obtained from human normal colon samples were cultured <i>in vitro</i> as detailed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0043379#s2" target="_blank"><i>Materials and Methods</i></a>, and stained with PKH26. …”

THE ACTION OF SERICIN PROTEIN ON INITIAL NERVE REPAIR, ASSOCIATED OR NOT WITH SWIMMING IN WISTAR RATS by Jean Carlos Debastiani (5186363)

“…There was improvement of allodynia and a decrease in the pain at the site of the surgical incision, possibly linked to an aquatic effect. …”

Does humic acid foliar application affect growth and nutrient status of water stressed maize? by Britta Pitann (18118531)

“…This is contradicting SPAD readings, which showed a significant decrease over time under submergence, but not under drought. …”